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Protein Ontology report - catenin beta-1 isoform 1 phosphorylated 1
PR:000030191 - http://purl.obolibrary.org/obo/PR_000030191
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000030191   
  PRO namecatenin beta-1 isoform 1 phosphorylated 1 
  Synonyms
PRO-Short-label: EXACT:CTNNB1/iso:1/Phos:1
  Definition"A catenin beta-1 isoform 1 that has been phosphorylated in two of the PAK1 consensus site (RXS/T). Example: UniProtKB:P35222-1, Ser-663/Ser-675, MOD:00046." [PMID:22369945, PRO:IC] 
  PRO Categorymodification 
  ParentPR:000002319 catenin beta-1 isoform 1
PR:000037070 phosphoprotein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000030191
catenin beta-1 isoform 1 phosphorylated 1
CTNNB1/iso:1/Phos:1
"A catenin beta-1 isoform 1 that has been phosphorylated in two of the PAK1 consensus site (RXS/T). Example: UniProtKB:P35222-1, Ser-663/Ser-675, MOD:00046." [PMID:22369945, PRO:IC]

organism-modification


PR:000030192
catenin beta-1 isoform 1 phosphorylated 1 (human)
hCTNNB1/iso:1/Phos:1
"A catenin beta-1 isoform 1 phosphorylated 1 in human. Phosphorylation at Ser-663 is found in many human colon cancer cells and tissues, which display a high PAK1 activity, or in response to Wnt3a stimulation. Ser-675 can be phosphorylated by either PAK1 or PKA. UniProtKB:P35222-1, Ser-663/Ser-675, MOD:00046." [PMID:22369945, PRO:IC]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000030192 hCTNNB1/iso:1/Phos:1
UniProtKB:P35222-1, Ser-663/Ser-675, MOD:00046		 acts_upstream_of_or_withinGO:0016055 Wnt signaling pathway PMID:22369945
enablesincreased GO:0003713 transcription coactivator activity relative to PR:000002862 CTNNB1/iso:1/UnMod PMID:22369945