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Protein Ontology report - NAD-dependent protein deacetylase sirtuin-3, mitochondrial
PR:000029756 - http://purl.obolibrary.org/obo/PR_000029756
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000029756   
  PRO nameNAD-dependent protein deacetylase sirtuin-3, mitochondrial 
  Synonyms
PRO-Short-label: EXACT:SIRT3
Gene-based: RELATED:SIR2L3
Other: EXACT:NAD-dependent protein delactylase sirtuin-3 | regulatory protein SIR2 homolog 3 | SIR2-like protein 3
  Definition"A protein that is a translation product of the human SIRT3 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2709
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000029756 NAD-dependent protein deacetylase sirtuin-3, mitochondrial
SIRT3

organism-gene


PR:Q8R104 NAD-dependent protein deacetylase sirtuin-3 (mouse)
mSIRT3

organism-sequence


PR:Q8R104-1 NAD-dependent protein deacetylase sirtuin-3 isoform 1 (mouse)
mSIRT3/iso:1
Yes
organism-sequence


PR:Q8R104-2 NAD-dependent protein deacetylase sirtuin-3 isoform 2 (mouse)
mSIRT3/iso:2
Yes
organism-gene


PR:Q9NTG7 NAD-dependent protein deacetylase sirtuin-3, mitochondrial (human)
hSIRT3

organism-sequence


PR:Q9NTG7-1 NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform h1 (human)
hSIRT3/iso:h1

organism-sequence


PR:Q9NTG7-2 NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform h2 (human)
hSIRT3/iso:h2

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0006476 protein deacetylationPR:Q8R104-1 mSIRT3/iso:1 MGI_ref:4830236; PMID:19241369

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0032041 histone H3K14 deacetylase activity, NAD-dependentPR:Q8R104-1 mSIRT3/iso:1 MGI_ref:4830236; PMID:19241369
NOT GO:0032041 histone H3K14 deacetylase activity, NAD-dependentPR:Q8R104-2 mSIRT3/iso:2 MGI_ref:1926994; PMID:11056054

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005737 cytoplasmPR:Q8R104-2 mSIRT3/iso:2 MGI_ref:1926994; PMID:11056054
GO:0005739 mitochondrionPR:Q8R104-1 mSIRT3/iso:1 MGI_ref:4830236; PMID:19241369