back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - NAD-dependent protein deacetylase sirtuin-3, mitochondrial
PR:000029756 - http://purl.obolibrary.org/obo/PR_000029756
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000029756   
  PRO nameNAD-dependent protein deacetylase sirtuin-3, mitochondrial 
  Synonyms
PRO-Short-label: EXACT:SIRT3
Gene-based: RELATED:SIR2L3
Other: EXACT:NAD-dependent protein delactylase sirtuin-3 | regulatory protein SIR2 homolog 3 | SIR2-like protein 3
  Definition"A protein that is a translation product of the human SIRT3 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
IUPHARobj:2709
Back to top
Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000029756

NAD-dependent protein deacetylase sirtuin-3, mitochondrial

SIRT3


"A protein that is a translation product of the human SIRT3 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q8R104

NAD-dependent protein deacetylase sirtuin-3 (mouse)

mSIRT3


"An NAD-dependent protein deacetylase sirtuin-3, mitochondrial that is encoded in the genome of mouse." [OMA:Q8R104, PRO:DNx]


organism-sequence



PR:Q8R104-1

NAD-dependent protein deacetylase sirtuin-3 isoform 1 (mouse)

mSIRT3/iso:1


"An NAD-dependent protein deacetylase sirtuin-3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8R104-1." [PMID:19241369, PRO:HJD]

Yes

organism-sequence



PR:Q8R104-2

NAD-dependent protein deacetylase sirtuin-3 isoform 2 (mouse)

mSIRT3/iso:2


"An NAD-dependent protein deacetylase sirtuin-3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8R104-2." [PMID:16141072, PRO:HJD]

Yes

organism-gene



PR:Q9NTG7

NAD-dependent protein deacetylase sirtuin-3, mitochondrial (human)

hSIRT3


"An NAD-dependent protein deacetylase sirtuin-3, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9NTG7]


organism-sequence



PR:Q9NTG7-1

NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform h1 (human)

hSIRT3/iso:h1


"An NAD-dependent protein deacetylase sirtuin-3, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NTG7-1." [PRO:DNx, UniProtKB:Q9NTG7]


organism-sequence



PR:Q9NTG7-2

NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform h2 (human)

hSIRT3/iso:h2


"An NAD-dependent protein deacetylase sirtuin-3, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NTG7-2." [PRO:DNx, UniProtKB:Q9NTG7]


Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q8R104-1 mSIRT3/iso:1 acts_upstream_of_or_withinGO:0006476 protein deacetylation MGI_ref:4830236; PMID:19241369
enablesGO:0032041 histone H3K14 deacetylase activity, NAD-dependent MGI_ref:4830236; PMID:19241369
located_inGO:0005739 mitochondrion MGI_ref:4830236; PMID:19241369
PR:Q8R104-2 mSIRT3/iso:2 enablesNOT GO:0032041 histone H3K14 deacetylase activity, NAD-dependent MGI_ref:1926994; PMID:11056054
located_inGO:0005737 cytoplasm MGI_ref:1926994; PMID:11056054