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Protein Ontology report - neurexin-1-alpha
PR:000029250 - http://purl.obolibrary.org/obo/PR_000029250
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000029250   
  PRO nameneurexin-1-alpha 
  Synonyms
PRO-Short-label: EXACT:NRXN1-alpha
Other: EXACT:neurexin I-alpha
  Definition"A neurexin-1 that is translated from the upstream promoter, yielding proteins with EGF-like domains." [PRO:DAN, Wikipedia:NRXN1
  PRO Categoryseqgroup 
  ParentPR:000011571 neurexin-1
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
seqgroup



PR:000029250

neurexin-1-alpha

NRXN1-alpha


"A neurexin-1 that is translated from the upstream promoter, yielding proteins with EGF-like domains." [PRO:DAN, Wikipedia:NRXN1]


sequence



PR:000026807

neurexin-1-alpha isoform a1

NRXN1/iso:a1


"A neurexin-1-alpha that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9CS84-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:Q63372-1

neurexin-1-alpha isoform a1 (rat)

rNRXN1/iso:a1


"A neurexin-1-alpha isoform a1 that is encoded in the genome of rat." [PRO:DAN]


organism-sequence



PR:Q9CS84-1

neurexin-1-alpha isoform a1 (mouse)

mNRXN1/iso:a1


"A neurexin-1-alpha isoform a1 that is encoded in the genome of mouse." [PMID:10408888, PMID:16141072, PRO:HJD]

Yes

sequence



PR:000026809

neurexin-1-alpha isoform a2

NRXN1/iso:a2


"A neurexin-1-alpha that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9CS84-2 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:Q9CS84-2

neurexin-1-alpha isoform a2 (mouse)

mNRXN1/iso:a2


"A neurexin-1-alpha isoform a2 that is encoded in the genome of mouse." [PMID:10408888, PMID:16141072, PRO:HJD]


sequence



PR:000026811

neurexin-1-alpha isoform a3

NRXN1/iso:a3


"A neurexin-1-alpha that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9CS84-3 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:Q9CS84-3

neurexin-1-alpha isoform a3 (mouse)

mNRXN1/iso:3a


"A neurexin-1-alpha isoform a3 that is encoded in the genome of mouse." [PMID:10408888, PMID:16141072, PRO:HJD]


organism-sequence



PR:Q9ULB1-2

neurexin-1-alpha isoform a3 (human)

hNRXN1/iso:a3


"A neurexin-1-alpha isoform a3 that is encoded in the genome of human." [PMID:11944992, PRO:DAN]


sequence



PR:000028822

neurexin-1-alpha isoform a4

NRXN1/iso:a4


"A neurexin-1-alpha that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9CS84-4 or a 1:1 ortholog thereof." [PRO:DAN]


organism-sequence



PR:Q9CS84-4

neurexin-1-alpha isoform a4 (mouse)

mNRXN1/iso:a4


"A neurexin-1-alpha isoform a4 that is encoded in the genome of mouse." [PRO:DAN, UniProtKB:Q9CS84-4]


sequence



PR:000028823

neurexin-1-alpha isoform a5

NRXN1/iso:a5


"A neurexin-1-alpha that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9CS84-5 or a 1:1 ortholog thereof." [PRO:DAN]


organism-sequence



PR:Q9CS84-5

neurexin-1-alpha isoform a5 (mouse)

mNRXN1/iso:a5


"A neurexin-1-alpha isoform a5 that is encoded in the genome of mouse." [PRO:DAN, UniProtKB:Q9CS84-5]


organism-sequence



PR:Q9ULB1-1

neurexin-1-alpha isoform a5 (human)

hNRXN1/iso:a5


"A neurexin-1-alpha isoform a5 that is encoded in the genome of human." [PRO:DAN]


sequence



PR:000028828

neurexin-1-alpha isoform a6

NRXN1/iso:a6


"A neurexin-1-alpha that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9ULB1-3 or a 1:1 ortholog thereof." [PRO:DAN]


organism-sequence



PR:Q9ULB1-3

neurexin-1-alpha isoform a6 (human)

hNRXN1/iso:a6


"A neurexin-1-alpha isoform a6 that is encoded in the genome of human." [PRO:DAN]


organism-seqgroup



PR:Q63372

neurexin-1-alpha (rat)

rNRXN1-alpha


"A neurexin-1-alpha that is encoded in the genome of rat." [PRO:DAN, UniProtKB:Q63372]


organism-sequence



PR:Q63372-1

neurexin-1-alpha isoform a1 (rat)

rNRXN1/iso:a1


"A neurexin-1-alpha isoform a1 that is encoded in the genome of rat." [PRO:DAN]


organism-sequence



PR:Q63372-10

neurexin-1-alpha isoform a15 (rat)

rNRXN1/iso:a15


"A neurexin-1-alpha (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63372-10." [PRO:DNx, UniProtKB:Q63372]


organism-sequence



PR:Q63372-11

neurexin-1-alpha isoform a16 (rat)

rNRXN1/iso:a16


"A neurexin-1-alpha (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63372-11." [PRO:DNx, UniProtKB:Q63372]


organism-sequence



PR:Q63372-12

neurexin-1-alpha isoform a17 (rat)

rNRXN1/iso:a17


"A neurexin-1-alpha (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63372-12." [PRO:DNx, UniProtKB:Q63372]


organism-sequence



PR:Q63372-13

neurexin-1-alpha isoform a18 (rat)

rNRXN1/iso:a18


"A neurexin-1-alpha (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63372-13." [PRO:DNx, UniProtKB:Q63372]


organism-sequence



PR:Q63372-2

neurexin-1-alpha isoform a7 (rat)

rNRXN1/iso:a7


"A neurexin-1-alpha (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63372-2." [PRO:DNx, UniProtKB:Q63372]


organism-sequence



PR:Q63372-3

neurexin-1-alpha isoform a8 (rat)

rNRXN1/iso:a8


"A neurexin-1-alpha (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63372-3." [PRO:DNx, UniProtKB:Q63372]


organism-sequence



PR:Q63372-4

neurexin-1-alpha isoform a9 (rat)

rNRXN1/iso:a9


"A neurexin-1-alpha (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63372-4." [PRO:DNx, UniProtKB:Q63372]


organism-sequence



PR:Q63372-5

neurexin-1-alpha isoform a10 (rat)

rNRXN1/iso:a10


"A neurexin-1-alpha (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63372-5." [PRO:DNx, UniProtKB:Q63372]


organism-sequence



PR:Q63372-6

neurexin-1-alpha isoform a11 (rat)

rNRXN1/iso:a11


"A neurexin-1-alpha (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63372-6." [PRO:DNx, UniProtKB:Q63372]


organism-sequence



PR:Q63372-7

neurexin-1-alpha isoform a12 (rat)

rNRXN1/iso:a12


"A neurexin-1-alpha (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63372-7." [PRO:DNx, UniProtKB:Q63372]


organism-sequence



PR:Q63372-8

neurexin-1-alpha isoform a13 (rat)

rNRXN1/iso:a13


"A neurexin-1-alpha (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63372-8." [PRO:DNx, UniProtKB:Q63372]


organism-sequence



PR:Q63372-9

neurexin-1-alpha isoform a14 (rat)

rNRXN1/iso:a14


"A neurexin-1-alpha (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63372-9." [PRO:DNx, UniProtKB:Q63372]


organism-seqgroup



PR:Q9CS84

neurexin-1-alpha (mouse)

mNRXN1-alpha


"A neurexin-1-alpha that is encoded in the genome of mouse." [PRO:DAN, UniProtKB:Q9CS84]


organism-sequence



PR:Q9CS84-1

neurexin-1-alpha isoform a1 (mouse)

mNRXN1/iso:a1


"A neurexin-1-alpha isoform a1 that is encoded in the genome of mouse." [PMID:10408888, PMID:16141072, PRO:HJD]

Yes

organism-sequence



PR:Q9CS84-2

neurexin-1-alpha isoform a2 (mouse)

mNRXN1/iso:a2


"A neurexin-1-alpha isoform a2 that is encoded in the genome of mouse." [PMID:10408888, PMID:16141072, PRO:HJD]


organism-sequence



PR:Q9CS84-3

neurexin-1-alpha isoform a3 (mouse)

mNRXN1/iso:3a


"A neurexin-1-alpha isoform a3 that is encoded in the genome of mouse." [PMID:10408888, PMID:16141072, PRO:HJD]


organism-sequence



PR:Q9CS84-4

neurexin-1-alpha isoform a4 (mouse)

mNRXN1/iso:a4


"A neurexin-1-alpha isoform a4 that is encoded in the genome of mouse." [PRO:DAN, UniProtKB:Q9CS84-4]


organism-sequence



PR:Q9CS84-5

neurexin-1-alpha isoform a5 (mouse)

mNRXN1/iso:a5


"A neurexin-1-alpha isoform a5 that is encoded in the genome of mouse." [PRO:DAN, UniProtKB:Q9CS84-5]


organism-seqgroup



PR:Q9DDD0

neurexin-1-alpha (chicken)

chick-NRXN1-alpha


"A neurexin-1-alpha that is encoded in the genome of chicken." [PRO:DAN, UniProtKB:Q9DDD0]


organism-seqgroup



PR:Q9ULB1

neurexin-1-alpha (human)

hNRXN1-alpha


"A neurexin-1-alpha that is encoded in the genome of human." [PRO:DAN, UniProtKB:Q9ULB1]


organism-sequence



PR:Q9ULB1-1

neurexin-1-alpha isoform a5 (human)

hNRXN1/iso:a5


"A neurexin-1-alpha isoform a5 that is encoded in the genome of human." [PRO:DAN]


organism-sequence



PR:Q9ULB1-2

neurexin-1-alpha isoform a3 (human)

hNRXN1/iso:a3


"A neurexin-1-alpha isoform a3 that is encoded in the genome of human." [PMID:11944992, PRO:DAN]


organism-sequence



PR:Q9ULB1-3

neurexin-1-alpha isoform a6 (human)

hNRXN1/iso:a6


"A neurexin-1-alpha isoform a6 that is encoded in the genome of human." [PRO:DAN]


organism-modification



PR:000066771

neurexin-1-alpha phosphorylated 1 (human)

hNRXN1-alpha/Phos:1


"A neurexin-1-alpha (human) that has been phosphorylated on the residue at the position equivalent to Thr-1002 of the amino acid sequence represented by UniProtKB:Q9ULB1-1. Example: UniProtKB:Q9ULB1-1, Thr-1002, MOD:00047." [IEDB_epitope:2148060, PRO:DNx]


organism-modification



PR:000068244

neurexin-1-alpha phosphorylated 2 (human)

hNRXN1-alpha/Phos:2


"A neurexin-1-alpha (human) that has been phosphorylated on the residue at the position equivalent to Thr-811 of the amino acid sequence represented by UniProtKB:Q9ULB1-1. Example: UniProtKB:Q9ULB1-1, Thr-811, MOD:00047." [IEDB_epitope:2146052, PRO:DNx]


organism-modification



PR:000075620

neurexin-1-alpha phosphorylated 3 (human)

hNRXN1-alpha/Phos:3


"A neurexin-1-alpha (human) that has been phosphorylated on the residue at the position equivalent to Tyr-1420 of the amino acid sequence represented by UniProtKB:Q9ULB1-1. Example: UniProtKB:Q9ULB1-1, Tyr-1420, MOD:00048." [IEDB_epitope:2147088, PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9CS84-1 mNRXN1/iso:a1 acts_upstream_of_or_withinGO:0006904 vesicle docking involved in exocytosis MGI_ref:2154458; GO_REF:0000008
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus MGI_ref:5315831; PMID:22235116
located_inGO:0005886 plasma membrane MGI_ref:2154458; GO_REF:0000008