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Protein Ontology report - cGMP-dependent protein kinase 1
PR:000029120 - http://purl.obolibrary.org/obo/PR_000029120
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000029120   
  PRO namecGMP-dependent protein kinase 1 
  Synonyms
PRO-Short-label: EXACT:PRKG1
Gene-based: RELATED:PRKG1B | PRKGR1A | PRKGR1B
Other: EXACT:cGK 1 | cGK1 | cGKI | cGMP-dependent protein kinase I
  Definition"A protein that is a translation product of the human PRKG1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 11                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1492
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000029120
cGMP-dependent protein kinase 1
PRKG1
"A protein that is a translation product of the human PRKG1 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:O76360
cGMP-dependent protein kinase egl-4 (worm)
PRKG1 (worm)
"A cGMP-dependent protein kinase 1 that is encoded in the genome of worm." [OMA:O76360, PRO:DNx]

organism-sequence


PR:O76360-1
cGMP-dependent protein kinase egl-4 isoform a (worm)
PRKG1/iso:a (worm)
"A cGMP-dependent protein kinase egl-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O76360-1." [PRO:DNx, UniProtKB:O76360]

organism-sequence


PR:O76360-2
cGMP-dependent protein kinase egl-4 isoform b (worm)
PRKG1/iso:b (worm)
"A cGMP-dependent protein kinase egl-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O76360-2." [PRO:DNx, UniProtKB:O76360]

organism-sequence


PR:O76360-3
cGMP-dependent protein kinase egl-4 isoform c (worm)
PRKG1/iso:c (worm)
"A cGMP-dependent protein kinase egl-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O76360-3." [PRO:DNx, UniProtKB:O76360]

organism-sequence


PR:O76360-4
cGMP-dependent protein kinase egl-4 isoform d (worm)
PRKG1/iso:d (worm)
"A cGMP-dependent protein kinase egl-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O76360-4." [PRO:DNx, UniProtKB:O76360]

organism-sequence


PR:O76360-5
cGMP-dependent protein kinase egl-4 isoform e (worm)
PRKG1/iso:e (worm)
"A cGMP-dependent protein kinase egl-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O76360-5." [PRO:DNx, UniProtKB:O76360]

organism-sequence


PR:O76360-6
cGMP-dependent protein kinase egl-4 isoform f (worm)
PRKG1/iso:f (worm)
"A cGMP-dependent protein kinase egl-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O76360-6." [PRO:DNx, UniProtKB:O76360]

organism-gene


PR:P0C605
cGMP-dependent protein kinase 1 (mouse)
mPRKG1
"A cGMP-dependent protein kinase 1 that is encoded in the genome of mouse." [OMA:P0C605, PRO:DNx]

organism-sequence


PR:P0C605-1
cGMP-dependent protein kinase 1 isoform Alpha (mouse)
mPRKG1/iso:Alpha
"A cGMP-dependent protein kinase 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
Yes
organism-sequence


PR:P0C605-2
cGMP-dependent protein kinase 1 isoform Beta (mouse)
mPRKG1/iso:Beta
"A cGMP-dependent protein kinase 1 isoform 2 that is encoded in the genome of mouse." [PRO:DNx]

organism-gene


PR:Q13976
cGMP-dependent protein kinase 1 (human)
hPRKG1
"A cGMP-dependent protein kinase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13976]

organism-sequence


PR:Q13976-1
cGMP-dependent protein kinase 1 isoform Alpha (human)
hPRKG1/iso:Alpha
"A cGMP-dependent protein kinase 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-modification


PR:000085852
cGMP-dependent protein kinase 1 isoform Alpha, initiator methionine removed form (human)
hPRKG1/iso:Alpha/InitMet-
"A cGMP-dependent protein kinase 1 isoform Alpha (human) that has had the initiator methionine removed. UniProtKB:Q13976-1, 2-671." [PRO:DNx, Reactome:R-HSA-418370]

organism-sequence


PR:Q13976-2
cGMP-dependent protein kinase 1 isoform Beta (human)
hPRKG1/iso:Beta
"A cGMP-dependent protein kinase 1 isoform 2 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:Q13976-3
cGMP-dependent protein kinase 1 isoform h3 (human)
hPRKG1/iso:h3
"A cGMP-dependent protein kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13976-3." [PRO:DNx, UniProtKB:Q13976]

organism-modification


PR:000048926
cGMP-dependent protein kinase 1, initiator methionine removed form (human)
hPRKG1/InitMet-
"A cGMP-dependent protein kinase 1 (human) that has had the initiator methionine removed. UniProtKB:Q13976, 2-671." [PRO:DNx, Reactome:R-HSA-4551459]

organism-modification


PR:000085852
cGMP-dependent protein kinase 1 isoform Alpha, initiator methionine removed form (human)
hPRKG1/iso:Alpha/InitMet-
"A cGMP-dependent protein kinase 1 isoform Alpha (human) that has had the initiator methionine removed. UniProtKB:Q13976-1, 2-671." [PRO:DNx, Reactome:R-HSA-418370]

organism-modification


PR:000070065
cGMP-dependent protein kinase 1 deaminated 1 (human)
hPRKG1/Deam:1
"A cGMP-dependent protein kinase 1 (human) that has been deaminated on the residue at the position equivalent to Asn-489 of the amino acid sequence represented by UniProtKB:Q13976-1. Example: UniProtKB:Q13976-1, Asn-489, MOD:00684." [IEDB_epitope:1564503, PRO:DNx]

sequence


PR:000040490
cGMP-dependent protein kinase 1 isoform 1
PRKG1/iso:1
"A cGMP-dependent protein kinase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13976-1 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P0C605-1
cGMP-dependent protein kinase 1 isoform Alpha (mouse)
mPRKG1/iso:Alpha
"A cGMP-dependent protein kinase 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
Yes
organism-sequence


PR:Q13976-1
cGMP-dependent protein kinase 1 isoform Alpha (human)
hPRKG1/iso:Alpha
"A cGMP-dependent protein kinase 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-modification


PR:000085852
cGMP-dependent protein kinase 1 isoform Alpha, initiator methionine removed form (human)
hPRKG1/iso:Alpha/InitMet-
"A cGMP-dependent protein kinase 1 isoform Alpha (human) that has had the initiator methionine removed. UniProtKB:Q13976-1, 2-671." [PRO:DNx, Reactome:R-HSA-418370]

sequence


PR:000040491
cGMP-dependent protein kinase 1 isoform 2
PRKG1/iso:2
"A cGMP-dependent protein kinase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13976-2 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P0C605-2
cGMP-dependent protein kinase 1 isoform Beta (mouse)
mPRKG1/iso:Beta
"A cGMP-dependent protein kinase 1 isoform 2 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:Q13976-2
cGMP-dependent protein kinase 1 isoform Beta (human)
hPRKG1/iso:Beta
"A cGMP-dependent protein kinase 1 isoform 2 that is encoded in the genome of human." [PRO:DNx]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P0C605-1 mPRKG1/iso:Alpha acts_upstream_of_or_withinGO:0006468 protein phosphorylation MGI_ref:5447879; PMID:22922339
enablesGO:0004674 protein serine/threonine kinase activity MGI_ref:5447879; PMID:22922339