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Protein Ontology report - histone deacetylase 5 isoform 1
PR:000029003 - http://purl.obolibrary.org/obo/PR_000029003
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000029003   
  PRO namehistone deacetylase 5 isoform 1 
  Synonyms
PRO-Short-label: EXACT:HDAC5/iso:1
  Definition"A histone deacetylase 5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UQL6-1 or a 1:1 ortholog thereof." [PMID:11114197, PMID:11509672, PRO:ALI] 
  PRO Categorysequence 
  ParentPR:000008484 histone deacetylase 5
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 1                                        
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000029003
histone deacetylase 5 isoform 1
HDAC5/iso:1
"A histone deacetylase 5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UQL6-1 or a 1:1 ortholog thereof." [PMID:11114197, PMID:11509672, PRO:ALI]

organism-sequence


PR:Q9UQL6-1
histone deacetylase 5 isoform 1 (human)
hHDAC5/iso:1
"A histone deacetylase 5 isoform 1 that is encoded in the genome of human." [PRO:ALI]

organism-modification


PR:000029006
histone deacetylase 5 isoform 1 phosphorylated 1 (human)
hHDAC5/iso:1/Phos:1
"A histone deacetylase 5 isoform 1 phosphorylated 1 in human. This form is unable to form complexes with MEF2 proteins. UniProtKB:Q9UQL6-1, Ser-259/Ser-498, MOD:00046." [PMID:11114197, PMID:11509672, PRO:ALI]
Yes
modification


PR:000029005
histone deacetylase 5 isoform 1 phosphorylated 1
HDAC5/iso:1/Phos:1
"A histone deacetylase 5 isoform 1 that has been phosphorylated on Ser residues by activation of the CAMK signaling pathway. Example: UniProtKB:Q9UQL6-1, Ser-259/Ser-498, MOD:00046." [PMID:11114197, PMID:11509672, PRO:ALI]

organism-modification


PR:000029006
histone deacetylase 5 isoform 1 phosphorylated 1 (human)
hHDAC5/iso:1/Phos:1
"A histone deacetylase 5 isoform 1 phosphorylated 1 in human. This form is unable to form complexes with MEF2 proteins. UniProtKB:Q9UQL6-1, Ser-259/Ser-498, MOD:00046." [PMID:11114197, PMID:11509672, PRO:ALI]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000029006 hHDAC5/iso:1/Phos:1
UniProtKB:Q9UQL6-1, Ser-259/Ser-498, MOD:00046		 acts_upstream_of_or_withinGO:0007519 skeletal muscle tissue development PMID:11509672
enablesGO:0071889 14-3-3 protein binding PMID:11114197
located_inGO:0005737 cytoplasm PMID:11114197