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Protein Ontology report - sterol regulatory element-binding protein
PR:000028988 - http://purl.obolibrary.org/obo/PR_000028988
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000028988   
  PRO namesterol regulatory element-binding protein 
  Synonyms
Other: EXACT:sterol regulatory element-binding transcription factor
RELATED:SRE | SREBF | SREBP
  Definition"A protein that is a transmembrane protein where the N- and C-termini are both cytosolic, and the N terminus contains a basic helix-loop-helix domain (Pfam:PF00010) and functions as a transcription factor when cleaved off." [PMID:17303406] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene3                                                  Organism-Gene 9                                        
         Sequence1                                                  Organism-Sequence 16                                        
         Modification5                                                  Organism-Modification 14                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000028988 sterol regulatory element-binding protein
CDK19/iso:1

gene


PR:000015611 sterol regulatory element-binding protein 1
SREBF1

organism-gene


PR:P36956 sterol regulatory element-binding protein 1 (human)
hSREBF1

organism-sequence


PR:P36956-1 sterol regulatory element-binding protein 1 isoform 1 (human)
hSREBF1/iso:1

organism-modification


PR:000028630 sterol regulatory element-binding protein 1 isoform 1 acetylated 1 (human)
hSREBF1/iso:1/Ac:1

organism-sequence


PR:P36956-2 sterol regulatory element-binding protein 1 isoform hSREBP-1B (human)
hSREBF1/iso:hSREBP-1B

organism-sequence


PR:P36956-3 sterol regulatory element-binding protein 1 isoform hSREBP-1C (human)
hSREBF1/iso:hSREBP-1C

organism-sequence


PR:P36956-4 sterol regulatory element-binding protein 1 isoform h4 (human)
hSREBF1/iso:h4

organism-sequence


PR:P36956-5 sterol regulatory element-binding protein 1 isoform hSREBP-1aDelta (human)
hSREBF1/iso:hSREBP-1aDelta

organism-sequence


PR:P36956-6 sterol regulatory element-binding protein 1 isoform hSREBP-1cDelta (human)
hSREBF1/iso:hSREBP-1cDelta

organism-modification


PR:000045767 sterol regulatory element-binding protein 1 phosphorylated 1 (human)
hSREBF1/Phos:1

organism-modification


PR:000070261 sterol regulatory element-binding protein 1 methylated 1 (human)
hSREBF1/Me:1

organism-modification


PR:000072398 sterol regulatory element-binding protein 1 deaminated 1 (human)
hSREBF1/Deam:1

organism-modification


PR:000073406 sterol regulatory element-binding protein 1 deaminated 2 (human)
hSREBF1/Deam:2

organism-modification


PR:000083130 sterol regulatory element-binding protein 1 methylated 2 (human)
hSREBF1/Me:2

organism-modification


PR:000083933 sterol regulatory element-binding protein 1 deaminated 3 (human)
hSREBF1/Deam:3

organism-modification


PR:000084058 sterol regulatory element-binding protein 1 deaminated 4 (human)
hSREBF1/Deam:4

organism-modification


PR:000084129 sterol regulatory element-binding protein 1 phosphorylated 2 (human)
hSREBF1/Phos:2

organism-modification


PR:000084428 sterol regulatory element-binding protein 1 deaminated 5 (human)
hSREBF1/Deam:5

organism-gene


PR:P56720 sterol regulatory element-binding protein 1 (rat)
rSREBF1

organism-sequence


PR:P56720-1 sterol regulatory element-binding protein 1 isoform rSREBP-1C (rat)
rSREBF1/iso:rSREBP-1C

organism-sequence


PR:P56720-2 sterol regulatory element-binding protein 1 isoform rSREBP-1A (rat)
rSREBF1/iso:rSREBP-1A

organism-gene


PR:Q9WTN3 sterol regulatory element-binding protein 1 (mouse)
mSREBF1

organism-sequence


PR:Q9WTN3-1 sterol regulatory element-binding protein 1 isoform 1 (mouse)
mSREBF1/iso:1
Yes
organism-sequence


PR:Q9WTN3-2 sterol regulatory element-binding protein 1 isoform 2 (mouse)
mSREBF1/iso:2

organism-sequence


PR:Q9WTN3-3 sterol regulatory element-binding protein 1 isoform 3 (mouse)
mSREBF1/iso:3
Yes
organism-sequence


PR:Q9WTN3-4 sterol regulatory element-binding protein 1 isoform 4 (mouse)
mSREBF1/iso:4

sequence


PR:000028627 sterol regulatory element-binding protein 1 isoform 1
SREBF1/iso:1

organism-sequence


PR:P36956-1 sterol regulatory element-binding protein 1 isoform 1 (human)
hSREBF1/iso:1

organism-modification


PR:000028630 sterol regulatory element-binding protein 1 isoform 1 acetylated 1 (human)
hSREBF1/iso:1/Ac:1

modification


PR:000028629 sterol regulatory element-binding protein 1 isoform 1 acetylated 1
SREBF1/iso:1/Ac:1

organism-modification


PR:000028630 sterol regulatory element-binding protein 1 isoform 1 acetylated 1 (human)
hSREBF1/iso:1/Ac:1

modification


PR:000021563 sterol regulatory element-binding protein 1 proteolytic cleavage product
SREBF1/ClvPrd

gene


PR:000015612 sterol regulatory element-binding protein 2
SREBF2

organism-gene


PR:A3KNA7 sterol regulatory element-binding protein 2 (zebrafish)
z-SREBF2

organism-gene


PR:Q12772 sterol regulatory element-binding protein 2 (human)
hSREBF2

organism-sequence


PR:Q12772-1 sterol regulatory element-binding protein 2 isoform h1 (human)
hSREBF2/iso:h1

organism-sequence


PR:Q12772-2 sterol regulatory element-binding protein 2 isoform h2 (human)
hSREBF2/iso:h2

organism-modification


PR:000070498 sterol regulatory element-binding protein 2 methylated 1 (human)
hSREBF2/Me:1

organism-modification


PR:000082335 sterol regulatory element-binding protein 2 methylated 2 (human)
hSREBF2/Me:2

organism-gene


PR:Q3T1I5 sterol regulatory element-binding protein 2 (rat)
rSREBF2

organism-gene


PR:Q3U1N2 sterol regulatory element-binding protein 2 (mouse)
mSREBF2

organism-sequence


PR:Q3U1N2-1 sterol regulatory element-binding protein 2 isoform m1 (mouse)
mSREBF2/iso:m1

organism-sequence


PR:Q3U1N2-2 sterol regulatory element-binding protein 2 isoform m2 (mouse)
mSREBF2/iso:m2

organism-modification


PR:000085746 processed sterol regulatory element-binding protein 2 (mouse)
mSREBF2/processed

modification


PR:000021564 sterol regulatory element-binding protein 2 proteolytic cleavage product
SREBF2/ClvPrd

organism-modification


PR:000085746 processed sterol regulatory element-binding protein 2 (mouse)
mSREBF2/processed

gene


PR:000028989 sre1-type sterol regulatory element-binding protein 1
sre1

organism-gene


PR:000044709 sterol regulatory element-binding protein 1 (Schizosaccharomyces pombe)
Spom-sre1

organism-gene


PR:Q9UUD1 sterol regulatory element-binding protein 1 (Schizosaccharomyces pombe 972h-)
Spom972h-sre1

organism-modification


PR:000028992 Sre1N (Schizosaccharomyces pombe)
Spom-sre1/Clv:1

organism-gene


PR:Q9UUD1 sterol regulatory element-binding protein 1 (Schizosaccharomyces pombe 972h-)
Spom972h-sre1

modification


PR:000028990 sre1-type sterol regulatory element-binding protein 1 proteolytic cleavage product
sre1/ClvPrd

modification


PR:000028991 sre1-type sterol regulatory element-binding protein 1 cleaved 1
sre1/Clv:1

organism-modification


PR:000028992 Sre1N (Schizosaccharomyces pombe)
Spom-sre1/Clv:1

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9WTN3-1 mSREBF1/iso:1 enablesGO:0000976 transcription cis-regulatory region binding MGI_ref:2177036; PMID:11739104
PR:Q9WTN3-3 mSREBF1/iso:3 enablesGO:0000976 transcription cis-regulatory region binding MGI_ref:2177036; PMID:11739104