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Protein Ontology report - activated trypsin
PR:000028941 - http://purl.obolibrary.org/obo/PR_000028941
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000028941   
  PRO nameactivated trypsin 
  Synonyms
PRO-Short-label: EXACT:PRSS/ProPep-
  Definition"A trypsin, signal peptide removed form that has been activated by removal of the propeptide (activation peptide)." [PRO:DAN] 
  PRO Categorymodification 
  ParentPR:000036291 trypsin, signal peptide removed form
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification3                                                  Organism-Modification 23                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000028941
activated trypsin
PRSS/ProPep-
"A trypsin, signal peptide removed form that has been activated by removal of the propeptide (activation peptide)." [PRO:DAN]

modification


PR:000003018
prostate-specific antigen isoform 1 cleaved and glycosylated form
KLK3/iso:1/ClvGlyco+
"A prostate-specific antigen isoform 1, signal peptide removed form that has had the propeptide removed and that includes at least one glycosylated residue." [PRO:CNA]

modification


PR:000003019
prostate-specific antigen isoform 1 cleaved and N-glycosylated 1
KLK3/iso:1/ClvNGlyco:1
"A prostate-specific antigen isoform 1 cleaved and glycosylated form that contains an N-glycosylated Asn residue within the glycosylation consensus sequence near its N terminus. Example: UniProtKB:P07288-1, 25-261, Asn-69, MOD:00160." [PMID:2422647, PMID:3691515, PRO:CNA, PRO:DAN]

organism-modification


PR:000037245
chymotrypsin-like elastase family member 2A, mature form (mouse)
mCELA2A/mature
"A chymotrypsin-like elastase family member 2A, pro-form (mouse) that has had the activation peptide removed by proteolytic cleavage. UniProtKB:P05208, 31-271." [PMID:20179351, PMID:3641189, PRO:KRC]
Yes
organism-modification


PR:000050073
tryptase alpha/beta-1, mature form (human)
hTPSAB1/mature
"A tryptase alpha/beta-1 (human) that has had the signal peptide and propeptide removed. Example: UniProtKB:Q15661-1, 31-275." [PRO:DNx, UniProtKB:Q15661]

organism-modification


PR:000050080
tryptase beta-2, mature form (human)
hTPSB2/mature
"A tryptase beta-2 (human) that has had the signal peptide and propeptide removed. UniProtKB:P20231, 31-275." [PRO:DNx, UniProtKB:P20231]

organism-modification


PR:000059609
chymotrypsin-C isoform 1 active form (mouse)
mCTRC/iso:1/active
"A chymotrypsin-C isoform 1 (mouse) that has had the signal peptide and the propeptide removed. Propeptide (aka activation peptide) cleavage is mediated by trypsin, and yields the mature active form. UniProtKB:Q3SYP2-1, 30-268." [PRO:KRC]

organism-modification


PR:000066317
kallikrein-8, mature form (human)
hKLK8/mature
"A kallikrein-8 (human) that has had the signal peptide and propeptide removed. Example: UniProtKB:O60259-1, 33-260." [PRO:DNx, Reactome:R-HSA-8850833]

organism-modification


PR:000067395
complement factor D, mature form (human)
hCFD/mature
"A complement factor D (human) that has had the signal peptide and propeptide removed. UniProtKB:P00746, 26-253." [PRO:DNx, Reactome:R-HSA-139852, Reactome:R-HSA-51919, Reactome:R-HSA-6804790, Reactome:R-HSA-6804805]

organism-modification


PR:000070514
kallikrein-1, mature form (human)
hKLK1/mature
"A kallikrein-1 (human) that has had the signal peptide and propeptide removed. Example: UniProtKB:P06870-1, 25-262." [PRO:DNx, Reactome:R-HSA-2990870]

organism-modification


PR:000070532
prostate-specific antigen, mature form (human)
hKLK3/mature
"A prostate-specific antigen (human) that has had the signal peptide and propeptide removed. Example: UniProtKB:P07288-1, 25-261." [PRO:DNx, Reactome:R-HSA-381416]

organism-modification


PR:000070737
trypsin-2, mature form (human)
hPRSS2/mature
"A trypsin-2 (human) that has had the signal peptide and propeptide removed. UniProtKB:P07478, 24-247." [PRO:DNx, Reactome:R-HSA-1460243, Reactome:R-HSA-6799229]

organism-modification


PR:000071040
chymotrypsin-like elastase family member 2A, mature form (human)
hCELA2A/mature
"A chymotrypsin-like elastase family member 2A (human) that has had the signal peptide and propeptide removed. UniProtKB:P08217, 29-269." [PRO:DNx, Reactome:R-HSA-8849616, Reactome:R-HSA-8934818]

organism-modification


PR:000071078
neutrophil elastase, mature form (human)
hELANE/mature
"A neutrophil elastase (human) that has had the signal peptide and propeptide removed. UniProtKB:P08246, 30-267." [PRO:DNx, Reactome:R-HSA-1602474, Reactome:R-HSA-6799238, Reactome:R-HSA-6800918, Reactome:R-HSA-9710109]

organism-modification


PR:000071760
granzyme B, mature form (human)
hGZMB/mature
"A granzyme B (human) that has had the signal peptide and propeptide removed. UniProtKB:P10144, 21-247." [PRO:DNx, Reactome:R-HSA-55915, Reactome:R-HSA-6807037]

organism-modification


PR:000073907
kallikrein-2, mature form (human)
hKLK2/mature
"A kallikrein-2 (human) that has had the signal peptide and propeptide removed. Example: UniProtKB:P20151-1, 25-261." [PRO:DNx, Reactome:R-HSA-1604753]

organism-modification


PR:000073944
azurocidin, mature form (human)
hAZU1/mature
"An azurocidin (human) that has had the signal peptide and all propeptides removed. UniProtKB:P20160, 27-248." [PRO:DNx, Reactome:R-HSA-6798767, Reactome:R-HSA-6806193]

organism-modification


PR:000074268
granzyme H, mature form (human)
hGZMH/mature
"A granzyme H (human) that has had the signal peptide and propeptide removed. Example: UniProtKB:P20718-1, 21-246." [PRO:DNx, Reactome:R-HSA-2990875]

organism-modification


PR:000074937
chymase, mature form (human)
hCMA1/mature
"A chymase (human) that has had the signal peptide and propeptide removed. Example: UniProtKB:P23946-1, 22-247." [PRO:DNx, Reactome:R-HSA-708327]

organism-modification


PR:000074979
myeloblastin, mature form (human)
hPRTN3/mature
"A myeloblastin (human) that has had the signal peptide and all propeptides removed. UniProtKB:P24158, 28-248." [PRO:DNx, Reactome:R-HSA-448623, Reactome:R-HSA-5610100, Reactome:R-HSA-6799223, Reactome:R-HSA-6801682]

organism-modification


PR:000075628
trypsin-3, mature form (human)
hPRSS3/mature
"A trypsin-3 (human) that has had the signal peptide and propeptide removed. Example: UniProtKB:P35030-1, 81-304." [PRO:DNx, Reactome:R-HSA-1460244, Reactome:R-HSA-6800432]

organism-modification


PR:000076167
kallikrein-7, mature form (human)
hKLK7/mature
"A kallikrein-7 (human) that has had the signal peptide and propeptide removed. Example: UniProtKB:P49862-1, 30-253." [PRO:DNx, Reactome:R-HSA-3827967, Reactome:R-HSA-9727975]

organism-modification


PR:000076290
granzyme M, mature form (human)
hGZMM/mature
"A granzyme M (human) that has had the signal peptide and propeptide removed. UniProtKB:P51124, 26-257." [PRO:DNx, Reactome:R-HSA-2975823]

organism-modification


PR:000081268
serine protease 41, mature GPI-anchored 1 (human)
hPRSS41/mature/anchored:1
"A serine protease 41 (human) that has had the signal peptide and all propeptides removed, and that has been GPI-anchored on the residue at the position equivalent to Ser-299 of the amino acid sequence represented by UniProtKB:Q7RTY9. UniProtKB:Q7RTY9, 55-299, Ser-299, MOD:00171." [PRO:DNx, Reactome:R-HSA-8940698]

organism-modification


PR:000085370
kallikrein-14, mature form (human)
hKLK14/mature
"A kallikrein-14 (human) that has had the signal peptide and propeptide removed. UniProtKB:Q9P0G3, 41-267." [PRO:DNx, Reactome:R-HSA-5694595]

organism-modification


PR:000086024
testisin, mature GPI-anchored 1 (human)
hPRSS21/mature/anchored:1
"A testisin (human) that has had the signal peptide and all propeptides removed, and that has been GPI-anchored on the residue at the position equivalent to Ser-288 of the amino acid sequence represented by UniProtKB:Q9Y6M0-1. Example: UniProtKB:Q9Y6M0-1, 42-288, Ser-288, MOD:00171." [PRO:DNx, Reactome:R-HSA-8940704]

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0006508 proteolysisPR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
GO:0061436 establishment of skin barrierPR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0017171 serine hydrolase activityPR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351
PR:000037245 mCELA2A/mature MGI_ref:4440399; PMID:20179351