Home
|
Linked Open Data
|
Browse
|
Search
|
Statistics
|
Download
RACE-PRO
PRO tracker
Community
PRO Consortium
Publications
Documentation
Protein Ontology report - cellular tumor antigen p53 isoform 1 sumoylated 1
PR:000027840 -
http://purl.obolibrary.org/obo/PR_000027840
Protein Forms
Complex
Ontology Information
Show OBO stanza
PRO ID
PR:000027840
PRO name
cellular tumor antigen p53 isoform 1 sumoylated 1
Synonyms
PRO-Short-label
:
EXACT:
TP53/iso:1/Sumo:1
Definition
"A cellular tumor antigen p53 isoform 1 that has been sumoylated on a conserved Lys residue located within the regulatory C-terminal domain. While p53 sumoylation at Lys386 inhibits p300 mediated p53 acetylation (at Lys382 and Lys 373), p53 acetylation by p300 remains permissive for subsequent Lys386 sumoylation. Lys386 sumoylated p53 exists as a tetramer in solution. Example:
UniProtKB:P04637-1
, Lys-386,
MOD:01149
." [
PMID:19339993
, PRO:PD]
PRO Category
modification
Parent
PR:000003036
cellular tumor antigen p53 isoform 1
PR:000037078
sumoylated protein
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
Back to top
Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000027840
cellular tumor antigen p53 isoform 1 sumoylated 1
TP53/iso:1/Sumo:1
"A cellular tumor antigen p53 isoform 1 that has been sumoylated on a conserved Lys residue located within the regulatory C-terminal domain. While p53 sumoylation at Lys386 inhibits p300 mediated p53 acetylation (at Lys382 and Lys 373), p53 acetylation by p300 remains permissive for subsequent Lys386 sumoylation. Lys386 sumoylated p53 exists as a tetramer in solution. Example: UniProtKB:P04637-1, Lys-386, MOD:01149." [PMID:19339993, PRO:PD]
organism-modification
PR:000027841
cellular tumor antigen p53 isoform 1 sumoylated 1 (human)
hTP53/iso:1/Sumo:1
"A cellular tumor antigen p53 isoform 1 sumoylated 1 in human. UniProtKB:P04637-1, Lys-386, MOD:01149." [PMID:19339993, PRO:PD]
Yes
Back to top
TP53/iso:1/Sumo:1
forms found in complexes
TP53/iso:1/Sumo:1
Component
Complexes
PR:000027841
hTP53/iso:1/Sumo:1
PR:000027844
p53 complex sumoylated 1 (human)