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Protein Ontology report - cellular tumor antigen p53 isoform 1 phosphorylated 8
PR:000027830 -
http://purl.obolibrary.org/obo/PR_000027830
Protein Forms
Ontology Information
Show OBO stanza
PRO ID
PR:000027830
PRO name
cellular tumor antigen p53 isoform 1 phosphorylated 8
Synonyms
PRO-Short-label
:
EXACT:
TP53/iso:1/Phos:8
Definition
"A cellular tumor antigen p53 isoform 1 that has been phosphorylated at two Ser residues, one located in the DNA-binding domain and the other within the nuclear localization signal of the C-terminus of p53. Phosphorylation at Ser-215 hinders DNA binding and transactivation activity of p53. Example:
UniProtKB:P04637-1
, Ser-215/Ser-315,
MOD:00046
." [
PMID:15469940
, PRO:PD]
PRO Category
modification
Parent
PR:000003038
cellular tumor antigen p53 isoform 1 phosphorylated form
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
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OLS:
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Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000027830
cellular tumor antigen p53 isoform 1 phosphorylated 8
TP53/iso:1/Phos:8
"A cellular tumor antigen p53 isoform 1 that has been phosphorylated at two Ser residues, one located in the DNA-binding domain and the other within the nuclear localization signal of the C-terminus of p53. Phosphorylation at Ser-215 hinders DNA binding and transactivation activity of p53. Example: UniProtKB:P04637-1, Ser-215/Ser-315, MOD:00046." [PMID:15469940, PRO:PD]
organism-modification
PR:000027831
cellular tumor antigen p53 isoform 1 phosphorylated 8 (human)
hTP53/iso:1/Phos:8
"A cellular tumor antigen p53 isoform 1 phosphorylated 8 in human. UniProtKB:P04637-1, Ser-215/Ser-315, MOD:00046." [PMID:15469940, PRO:PD]
