|
|
 |
 |
|  |  |
 |  |  |  |  |  |  |  |
family
 |


|
 PR:000027804 |
   basic helix-loop-helix transcription factor HAND
 |
   mHAND1/iso:1/PhosRes-
 |
  "A protein that belongs to the clade A of the bHLH proteins (see PMID:20219281) with with a C-terminal copy of the helix-loop-helix DNA-binding domain (Pfam:PF00010), and it is the translation product of the human HAND1 or HAND2 genes, or 1:1 orthologs thereof." [PMID:12909338, PMID:20219281, PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |
 |  |  |  |  |  |
gene
 |


|
 PR:000008439 |
   heart- and neural crest derivatives-expressed protein 1
 |
   HAND1
 |
  "A basic helix-loop-helix transcription factor HAND that is a translation product of the human HAND1 gene or a 1:1 ortholog thereof." [PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
organism-gene
 |


|
 PR:O96004 |
   heart- and neural crest derivatives-expressed protein 1 (human)
 |
   hHAND1
 |
  "A heart- and neural crest derivatives-expressed protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O96004]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-sequence
 |


|
 PR:O96004-1 |
   heart- and neural crest derivatives-expressed protein 1 isoform 1 (human)
 |
   hHAND1/iso:1
 |
  "A heart- and neural crest derivatives-expressed protein 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
organism-gene
 |


|
 PR:P97832 |
   heart- and neural crest derivatives-expressed protein 1 (rat)
 |
   rHAND1
 |
  "A heart- and neural crest derivatives-expressed protein 1 that is encoded in the genome of rat." [OMA:P97832, PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-sequence
 |


|
 PR:P97832-1 |
   heart- and neural crest derivatives-expressed protein 1 isoform 1 (rat)
 |
   rHAND1/iso:1
 |
  "A heart- and neural crest derivatives-expressed protein 1 isoform 1 that is encoded in the genome of rat." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
organism-gene
 |


|
 PR:Q64279 |
   heart- and neural crest derivatives-expressed protein 1 (mouse)
 |
   mHAND1
 |
  "A heart- and neural crest derivatives-expressed protein 1 that is encoded in the genome of mouse." [OMA:Q64279, PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-sequence
 |


|
 PR:Q64279-1 |
   heart- and neural crest derivatives-expressed protein 1 isoform 1 (mouse)
 |
   mHAND1/iso:1
 |
  "A heart- and neural crest derivatives-expressed protein 1 isoform 1 that is encoded in the genome of mouse." [PMID:7791788, PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
organism-modification
 |


|
 PR:000027800 |
   heart- and neural crest derivatives-expressed protein 1 isoform 1 phosphorylated 1 (mouse)
 |
   mHAND1/iso:1/Phos:1
 |
  "A heart- and neural crest derivatives-expressed protein 1 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q64279-1, (Thr-107, MOD:00047 and/or Ser-109, MOD:00046)." [PMID:17891141, PRO:HJD]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
organism-modification
 |


|
 PR:000027802 |
   heart- and neural crest derivatives-expressed protein 1 isoform 1 unphosphorylated form (mouse)
 |
   mHAND1/iso:1/PhosRes-
 |
  "A heart- and neural crest derivatives-expressed protein 1 isoform 1 unphosphorylated form in mouse." [PMID:17891141, PRO:HJD]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-modification
 |


|
 PR:000085716 |
   heart- and neural crest derivatives-expressed protein 1 phosphorylated 1 (mouse)
 |
   mHAND1/Phos:1
 |
  "A heart- and neural crest derivatives-expressed protein 1 (mouse) that has been phosphorylated at the Ser and/or Thr residues within the KER[RQ]RTxS motif located at the N terminus of the bHLH domain. Example: UniProtKB:Q64279-1, (Thr-107, MOD:00047 and/or Ser-109, MOD:00046)." [PMID:21559426, PRO:DAN]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
organism-gene
 |


|
 PR:Q90691 |
   heart- and neural crest derivatives-expressed protein 1 (chicken)
 |
   chick-HAND1
 |
  "A heart- and neural crest derivatives-expressed protein 1 that is encoded in the genome of chicken." [OMA:Q90691, PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
sequence
 |


|
 PR:000027797 |
   heart- and neural crest derivatives-expressed protein 1 isoform 1
 |
   HAND1/iso:1
 |
  "A heart- and neural crest derivatives-expressed protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q64279-1 or a 1:1 ortholog thereof." [PMID:17891141, PMID:7791788, PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-sequence
 |


|
 PR:O96004-1 |
   heart- and neural crest derivatives-expressed protein 1 isoform 1 (human)
 |
   hHAND1/iso:1
 |
  "A heart- and neural crest derivatives-expressed protein 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-sequence
 |


|
 PR:P97832-1 |
   heart- and neural crest derivatives-expressed protein 1 isoform 1 (rat)
 |
   rHAND1/iso:1
 |
  "A heart- and neural crest derivatives-expressed protein 1 isoform 1 that is encoded in the genome of rat." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-sequence
 |


|
 PR:Q64279-1 |
   heart- and neural crest derivatives-expressed protein 1 isoform 1 (mouse)
 |
   mHAND1/iso:1
 |
  "A heart- and neural crest derivatives-expressed protein 1 isoform 1 that is encoded in the genome of mouse." [PMID:7791788, PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
organism-modification
 |


|
 PR:000027800 |
   heart- and neural crest derivatives-expressed protein 1 isoform 1 phosphorylated 1 (mouse)
 |
   mHAND1/iso:1/Phos:1
 |
  "A heart- and neural crest derivatives-expressed protein 1 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q64279-1, (Thr-107, MOD:00047 and/or Ser-109, MOD:00046)." [PMID:17891141, PRO:HJD]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
organism-modification
 |


|
 PR:000027802 |
   heart- and neural crest derivatives-expressed protein 1 isoform 1 unphosphorylated form (mouse)
 |
   mHAND1/iso:1/PhosRes-
 |
  "A heart- and neural crest derivatives-expressed protein 1 isoform 1 unphosphorylated form in mouse." [PMID:17891141, PRO:HJD]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
modification
 |


|
 PR:000027799 |
   heart- and neural crest derivatives-expressed protein 1 isoform 1 phosphorylated 1
 |
   HAND1/iso:1/Phos:1
 |
  "A heart- and neural crest derivatives-expressed protein 1 isoform 1 that has been phosphorylated at the Ser and/or Thr residues within the KER[RQ]RTxS motif located at the N terminus of the bHLH domain. Example: UniProtKB:Q64279-1, (Thr-107, MOD:00047 and/or Ser-109, MOD:00046)." [PMID:17891141, PRO:HJD]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
organism-modification
 |


|
 PR:000027800 |
   heart- and neural crest derivatives-expressed protein 1 isoform 1 phosphorylated 1 (mouse)
 |
   mHAND1/iso:1/Phos:1
 |
  "A heart- and neural crest derivatives-expressed protein 1 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q64279-1, (Thr-107, MOD:00047 and/or Ser-109, MOD:00046)." [PMID:17891141, PRO:HJD]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
modification
 |


|
 PR:000027801 |
   heart- and neural crest derivatives-expressed protein 1 isoform 1 unphosphorylated form
 |
   HAND1/iso:1/PhosRes-
 |
  "A heart- and neural crest derivatives-expressed protein 1 isoform 1 that lacks phosphorylated residues." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |  |  |
organism-modification
 |


|
 PR:000027802 |
   heart- and neural crest derivatives-expressed protein 1 isoform 1 unphosphorylated form (mouse)
 |
   mHAND1/iso:1/PhosRes-
 |
  "A heart- and neural crest derivatives-expressed protein 1 isoform 1 unphosphorylated form in mouse." [PMID:17891141, PRO:HJD]
 |

| 
|
|
|
 |
 |
|  |  |  |  |
 |  |  |  |  |  |
gene
 |


|
 PR:000008440 |
   heart- and neural crest derivatives-expressed protein 2
 |
   HAND2
 |
  "A basic helix-loop-helix transcription factor HAND that is a translation product of the human HAND2 gene or a 1:1 ortholog thereof." [PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
organism-gene
 |


|
 PR:P57102 |
   heart- and neural crest derivatives-expressed protein 2 (zebrafish)
 |
   z-HAND2
 |
  "A heart- and neural crest derivatives-expressed protein 2 that is encoded in the genome of zebrafish." [OMA:P57102, PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
organism-gene
 |


|
 PR:P61295 |
   heart- and neural crest derivatives-expressed protein 2 (rat)
 |
   rHAND2
 |
  "A heart- and neural crest derivatives-expressed protein 2 that is encoded in the genome of rat." [OMA:P61295, PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-sequence
 |


|
 PR:P61295-1 |
   heart- and neural crest derivatives-expressed protein 2 isoform 1 (rat)
 |
   rHAND2/iso:1
 |
  "A heart- and neural crest derivatives-expressed protein 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
organism-gene
 |


|
 PR:P61296 |
   heart- and neural crest derivatives-expressed protein 2 (human)
 |
   hHAND2
 |
  "A heart- and neural crest derivatives-expressed protein 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P61296]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-sequence
 |


|
 PR:P61296-1 |
   heart- and neural crest derivatives-expressed protein 2 isoform 1 (human)
 |
   hHAND2/iso:1
 |
  "A heart- and neural crest derivatives-expressed protein 2 isoform 1 that is encoded in the genome of human." [PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-sequence
 |


|
 PR:P61296-2 |
   heart- and neural crest derivatives-expressed protein 2 isoform h2 (human)
 |
   hHAND2/iso:h2
 |
  "A heart- and neural crest derivatives-expressed protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61296-2." [PRO:DNx, UniProtKB:P61296]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
organism-gene
 |


|
 PR:Q61039 |
   heart- and neural crest derivatives-expressed protein 2 (mouse)
 |
   mHAND2
 |
  "A heart- and neural crest derivatives-expressed protein 2 that is encoded in the genome of mouse." [OMA:Q61039, PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-sequence
 |


|
 PR:Q61039-1 |
   heart- and neural crest derivatives-expressed protein 2 isoform 1 (mouse)
 |
   mHAND2/iso:1
 |
  "A heart- and neural crest derivatives-expressed protein 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
organism-gene
 |


|
 PR:Q90690 |
   heart- and neural crest derivatives-expressed protein 2 (chicken)
 |
   chick-HAND2
 |
  "A heart- and neural crest derivatives-expressed protein 2 that is encoded in the genome of chicken." [OMA:Q90690, PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |  |
sequence
 |


|
 PR:000039937 |
   heart- and neural crest derivatives-expressed protein 2 isoform 1
 |
   HAND2/iso:1
 |
  "A heart- and neural crest derivatives-expressed protein 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61296-1 or a 1:1 ortholog thereof." [PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-sequence
 |


|
 PR:P61295-1 |
   heart- and neural crest derivatives-expressed protein 2 isoform 1 (rat)
 |
   rHAND2/iso:1
 |
  "A heart- and neural crest derivatives-expressed protein 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-sequence
 |


|
 PR:P61296-1 |
   heart- and neural crest derivatives-expressed protein 2 isoform 1 (human)
 |
   hHAND2/iso:1
 |
  "A heart- and neural crest derivatives-expressed protein 2 isoform 1 that is encoded in the genome of human." [PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |  |
organism-sequence
 |


|
 PR:Q61039-1 |
   heart- and neural crest derivatives-expressed protein 2 isoform 1 (mouse)
 |
   mHAND2/iso:1
 |
  "A heart- and neural crest derivatives-expressed protein 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
 |

| 
|
|
|