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Protein Ontology report - estrogen receptor isoform 1 phosphorylated 3
PR:000027753 -
http://purl.obolibrary.org/obo/PR_000027753
Protein Forms
Ontology Information
Show OBO stanza
PRO ID
PR:000027753
PRO name
estrogen receptor isoform 1 phosphorylated 3
Synonyms
PRO-Short-label
:
EXACT:
ESR1/iso:1/Phos:3
Definition
"An estrogen receptor isoform 1 that has been phosphorylated on a Ser residue in the N-terminal activation function 1 (AF1) domain (
Pfam:PF02159
). This phosphorylation site is involved in modulating the expression of genes downregulated by 17-beta-estradiol and 4-Hydroxytamoxifen. Example:
UniProtKB:P03372-1
, Ser-118,
MOD:00046
." [
Pfam:PF02159
,
PMID:17615152
, PRO:PD]
PRO Category
modification
Parent
PR:000027721
estrogen receptor isoform 1
PR:000037070
phosphoprotein
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000027753
estrogen receptor isoform 1 phosphorylated 3
ESR1/iso:1/Phos:3
"An estrogen receptor isoform 1 that has been phosphorylated on a Ser residue in the N-terminal activation function 1 (AF1) domain (Pfam:PF02159). This phosphorylation site is involved in modulating the expression of genes downregulated by 17-beta-estradiol and 4-Hydroxytamoxifen. Example: UniProtKB:P03372-1, Ser-118, MOD:00046." [Pfam:PF02159, PMID:17615152, PRO:PD]
organism-modification
PR:000027754
estrogen receptor isoform 1 phosphorylated 3 (human)
hESR1/iso:1/Phos:3
"An estrogen receptor isoform 1 phosphorylated 3 in human. UniProtKB:P03372-1, Ser-118, MOD:00046." [PMID:17615152, PRO:PD]
