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Protein Ontology report - CALCA gene translation product
PR:000027222 - http://purl.obolibrary.org/obo/PR_000027222
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000027222   
  PRO nameCALCA gene translation product 
  Synonyms
PRO-Short-label: EXACT:CALCA
Other: RELATED:CALC
  Definition"A protein that is a translation product of the human CALCA gene or a 1:1 ortholog thereof." [MGI:2151253, PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence2                                                  Organism-Sequence 9                                        
         Modification5                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000027222

CALCA gene translation product

CALCA


"A protein that is a translation product of the human CALCA gene or a 1:1 ortholog thereof." [MGI:2151253, PRO:CNA]


organism-gene



PR:000027223

CALCA gene translation product (mouse)

mCALCA


"A CALCA gene translation product that is encoded in the genome of mouse." [MGI:2151253, PRO:HJD]

Yes

organism-sequence



PR:P70160-1

calcitonin isoform 1 (mouse)

mCALCA/iso:1


"A calcitonin isoform 1 that is encoded in the genome of mouse." [PMID:8806650, PRO:HJD]

Yes

organism-sequence



PR:Q99JA0-1

calcitonin gene-related peptide 1 (mouse)

mCALCA/iso:CGRP1


"A calcitonin gene-related peptide 1 that is encoded in the genome of mouse." [PMID:11761712, PRO:HJD]

Yes

organism-gene



PR:000030026

CALCA gene translation product (human)

hCALCA


"A CALCA gene translation product that is encoded in the genome of human." [PRO:DNx, UniProtKB:P06881]


organism-seqgroup



PR:P01258

calcitonin isoforms 1/2 (human)

hCALCA/iso:[1/h2]


"A calcitonin (human), isoforms 1 and 2." [PRO:DAN, UniProtKB:P01258]






PR:P01258-1

calcitonin isoform 1 (human)











PR:P01258-2

calcitonin isoform h2 (human)







organism-sequence



PR:P01258-1

calcitonin isoform 1 (human)

hCALCA/iso:1


"A calcitonin isoform 1 that is encoded in the genome of human." [PRO:DAN]


organism-modification



PR:000050338

procalcitonin (human)

hCALCA/iso:1/SigPep-


"A procalcitonin in human. UniProtKB:P01258-1, 26-141." [PRO:DAN]


organism-sequence



PR:P01258-2

calcitonin isoform h2 (human)

hCALCA/iso:h2


"A CALCA gene translation product (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01258-2." [PRO:DNx, UniProtKB:P01258]


organism-sequence



PR:P06881-1

calcitonin gene-related peptide 1 (human)

hCALCA/iso:CGRP1


"A calcitonin gene-related peptide 1 that is encoded in the genome of human." [PRO:DAN]


organism-gene



PR:000036869

CALCA gene translation product (rat)

rCALCA


"A CALCA gene translation product that is encoded in the genome of rat." [PRO:DAN]


organism-sequence



PR:P01256-1

calcitonin gene-related peptide 1 (rat)

rCALCA/iso:CGRP1


"A calcitonin gene-related peptide 1 that is encoded in the genome of rat." [PRO:DAN]


organism-sequence



PR:P01257-1

calcitonin isoform 1 (rat)

rCALCA/iso:1


"A calcitonin isoform 1 that is encoded in the genome of rat." [PRO:DAN]


organism-gene



PR:000036870

CALCA gene translation product (chicken)

chick-CALCA


"A CALCA gene translation product that is encoded in the genome of chicken." [PRO:DAN]


organism-sequence



PR:P07660-1

calcitonin isoform 1 (chicken)

chick-CALCA/iso:1


"A calcitonin isoform 1 that is encoded in the genome of chicken." [PRO:DAN]


organism-sequence



PR:P10286-1

calcitonin gene-related peptide 1 (chicken)

chick-CALCA/iso:CGRP1


"A calcitonin gene-related peptide 1 that is encoded in the genome of chicken." [PRO:DAN]


sequence



PR:000027224

calcitonin isoform 1

CALCA/iso:1


"A CALCA gene translation product that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01258-1 or a 1:1 ortholog thereof." [PMID:8806650, PRO:CNA]


organism-sequence



PR:P01257-1

calcitonin isoform 1 (rat)

rCALCA/iso:1


"A calcitonin isoform 1 that is encoded in the genome of rat." [PRO:DAN]


organism-sequence



PR:P01258-1

calcitonin isoform 1 (human)

hCALCA/iso:1


"A calcitonin isoform 1 that is encoded in the genome of human." [PRO:DAN]


organism-modification



PR:000050338

procalcitonin (human)

hCALCA/iso:1/SigPep-


"A procalcitonin in human. UniProtKB:P01258-1, 26-141." [PRO:DAN]


organism-sequence



PR:P07660-1

calcitonin isoform 1 (chicken)

chick-CALCA/iso:1


"A calcitonin isoform 1 that is encoded in the genome of chicken." [PRO:DAN]


organism-sequence



PR:P70160-1

calcitonin isoform 1 (mouse)

mCALCA/iso:1


"A calcitonin isoform 1 that is encoded in the genome of mouse." [PMID:8806650, PRO:HJD]

Yes

modification



PR:000050333

procalcitonin

CALCA/iso:1/SigPep-


"A calcitonin isoform 1 that has had the signal peptide removed. Example: UniProtKB:P01258-1, 26-141." [PMID:10984072, PRO:DAN]


modification



PR:000050334

amino-procalcitonin

CALCA/iso:1/Clv:1


"A procalcitonin that is the N-terminal part after cleaved by prohormone convertase, followed by removal of the C-terminal lysine by carboxypeptidase. Example: UniProtKB:P01258-1, 26-82." [PMID:10984072, PRO:DAN]


modification



PR:000050335

immature calcitonin

CALCA/iso:1/Clv:2


"A procalcitonin that is the central part after cleaved by prohormone convertase, followed by removal of the N-terminal arginine by aminopeptidase and removal of the C-terminal lysine by carboxypeptidase. Example: UniProtKB:P01258-1, 85-117." [PMID:10984072, PRO:DAN]


modification



PR:000050337

mature calcitonin

CALCA/iso:1/Clv:4


"An immature calcitonin that has been amidated by peptidylglycine amidating monooxygenase, which removes the C-terminal glycine in the process. Example: UniProtKB:P01258-1, 85-116, Pro-116, MOD:00104." [PMID:10984072, PRO:DAN]


modification



PR:000050336

calcitonin carboxypeptide-I

CALCA/iso:1/Clv:3


"A procalcitonin that is the C-terminal part after cleaved by prohormone convertase, followed by removal of the N-terminal arginine by aminopeptidase. Example: UniProtKB:P01258-1, 26-82." [PMID:10984072, PRO:DAN]


organism-modification



PR:000050338

procalcitonin (human)

hCALCA/iso:1/SigPep-


"A procalcitonin in human. UniProtKB:P01258-1, 26-141." [PRO:DAN]


sequence



PR:000027226

calcitonin gene-related peptide 1

CALCA/iso:CGRP1


"A CALCA gene translation product that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06881-1 or a 1:1 ortholog thereof." [PMID:11761712, PRO:CNA, PRO:DAN]


organism-sequence



PR:P01256-1

calcitonin gene-related peptide 1 (rat)

rCALCA/iso:CGRP1


"A calcitonin gene-related peptide 1 that is encoded in the genome of rat." [PRO:DAN]


organism-sequence



PR:P06881-1

calcitonin gene-related peptide 1 (human)

hCALCA/iso:CGRP1


"A calcitonin gene-related peptide 1 that is encoded in the genome of human." [PRO:DAN]


organism-sequence



PR:P10286-1

calcitonin gene-related peptide 1 (chicken)

chick-CALCA/iso:CGRP1


"A calcitonin gene-related peptide 1 that is encoded in the genome of chicken." [PRO:DAN]


organism-sequence



PR:Q99JA0-1

calcitonin gene-related peptide 1 (mouse)

mCALCA/iso:CGRP1


"A calcitonin gene-related peptide 1 that is encoded in the genome of mouse." [PMID:11761712, PRO:HJD]

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000027223 mCALCA located_inGO:0005737 cytoplasm MGI_ref:3028786; PMID:14765981
PR:P70160-1 mCALCA/iso:1 located_inGO:0005615 extracellular space MGI_ref:3028786; PMID:14765981
GO:0005737 cytoplasm PMID:14765981
PR:Q99JA0-1 mCALCA/iso:CGRP1 acts_upstream_of_or_withinGO:0002027 regulation of heart rate MGI_ref:2445452; PMID:11717154
NOT GO:0007528 neuromuscular junction development MGI_ref:1345568; PMID:10532808
NOT GO:0008217 regulation of blood pressure MGI_ref:1345568; PMID:10532808
GO:0009408 response to heat MGI_ref:3603999; PMID:16118273
GO:0030279 negative regulation of ossification MGI_ref:3653805; PMID:15537449
GO:0031645 negative regulation of nervous system process MGI_ref:2445452; PMID:11717154
GO:0045776 negative regulation of blood pressure MGI_ref:2445452; PMID:11717154
GO:0045778 positive regulation of ossification MGI_ref:3653805; PMID:15537449
GO:0048265 response to pain MGI_ref:1933070; PMID:11276224
located_inGO:0030424 axon MGI_ref:1098517; PMID:1317267
GO:0043025 neuronal cell body MGI_ref:1316900; PMID:9838101