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Protein Ontology report - TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed myristoylated form
PR:000027200 - http://purl.obolibrary.org/obo/PR_000027200
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000027200   
  PRO nameTIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed myristoylated form 
  Synonyms
PRO-Short-label: EXACT:TICAM2/iso:1/InitMet-/MyrRes+
Other: EXACT:ticam2 myristoylated | TRAM myristoylated
  Definition"A TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed form that has been N-terminally myristoylated. Example: UniProtKB:Q86XR7-1, 2-235, Gly-2, MOD:00068." [PMID:16603631, PRO:CNA] 
  PRO Categorymodification 
  ParentPR:000027199 TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed form
PR:000037075 myristoylated protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000027200
TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed myristoylated form
TICAM2/iso:1/InitMet-/MyrRes+
"A TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed form that has been N-terminally myristoylated. Example: UniProtKB:Q86XR7-1, 2-235, Gly-2, MOD:00068." [PMID:16603631, PRO:CNA]

organism-modification


PR:000027201
TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed myristoylated 1 (human)
hTICAM2/iso:1/InitMet-/Myr:1
"A TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed myristoylated form in human that has been myristoylated at position 2 of the amino acid sequence represented by UniProtKB:Q86XR7-1. UniProtKB:Q86XR7-1, 2-235, Gly-2, MOD:00068." [PRO:CNA]

organism-modification


PR:000040891
TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed myristoylated and phosphorylated 1 (human)
hTICAM2/iso:1/InitMet-/MyrPhos:1
"A TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed myristoylated form in human that has been myristoylated at Gly-2 and phosphorylated at Ser-16 of the amino acid sequence represented by UniProtKB:Q86XR7-1. UniProtKB:Q86XR7-1, 2-235, Gly-2, MOD:00068|Ser-16, MOD:00046." [PMID:16757566, PRO:DAN]

Yes
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TICAM2/iso:1/InitMet-/MyrRes+ forms found in complexes   

TICAM2/iso:1/InitMet-/MyrRes+ Component
 Complexes
PR:000040891 hTICAM2/iso:1/InitMet-/MyrPhos:1 PR:000027208 ticam1:ticam2:activated TLR4 complex (human)
PR:000028678 ticam2:activated TLR4 complex (human)
PR:000028680 traf6:ticam1:ticam2:activated TLR4 complex (human)
PR:000035715 pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
PR:000035734 free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
PR:000035738 free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
PR:000036022 traf3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036024 rip1:ticam1:ticam2:activated TLR4 complex (human)
PR:000036027 sarm:ticam1:ticam2:activated TLR4 complex (human)
PR:000036030 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036034 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036036 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036038 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036041 K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036049 K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human)
PR:000036053 IKK complex:K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human)
PR:000036056 rip3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036058 rip1:rip3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036060 pro-caspase-8:fadd:rip1:ticam1:ticam2:activated TLR4 complex (human)
PR:000036123 p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human)
PR:000036124 p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human)