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Protein Ontology report - E3 ubiquitin-protein ligase CBL isoform 1
PR:000026186 - http://purl.obolibrary.org/obo/PR_000026186
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000026186   
  PRO nameE3 ubiquitin-protein ligase CBL isoform 1 
  Synonyms
PRO-Short-label: EXACT:CBL/iso:1
  Definition"An E3 ubiquitin-protein ligase CBL that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22681-1 or a 1:1 ortholog thereof." [PRO:CNx] 
  PRO Categorysequence 
  ParentPR:000005070 E3 ubiquitin-protein ligase CBL
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 1                                        
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000026186
E3 ubiquitin-protein ligase CBL isoform 1
CBL/iso:1
"An E3 ubiquitin-protein ligase CBL that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22681-1 or a 1:1 ortholog thereof." [PRO:CNx]

organism-sequence


PR:P22681-1
E3 ubiquitin-protein ligase CBL isoform 1 (human)
hCBL/iso:1
"An E3 ubiquitin-protein ligase CBL isoform 1 that is encoded in the genome of human." [PRO:CNx]

organism-modification


PR:000026223
E3 ubiquitin-protein ligase CBL isoform 1 phosphorylated 1 (human)
hCBL/iso:1/Phos:1
"An E3 ubiquitin-protein ligase CBL isoform 1 phosphorylated 1 in human. UniProtKB:P22681-1, Tyr-371, MOD:00048." [PMID:11997497, PMID:15117950, PRO:CNx]

modification


PR:000026188
E3 ubiquitin-protein ligase CBL isoform 1 phosphorylated 1
CBL/iso:1/Phos:1
"An E3 ubiquitin-protein ligase CBL isoform 1 that has been phosphorylated by tyrosine kinase receptors, such as EGFR or INSR. This tyrosine phosphorylation is necessary for activation of the ubiquitin ligase activity. Example: UniProtKB:P22681-1, Tyr-371, MOD:00048." [PMID:11997497, PMID:15117950, PRO:CNx, Reactome:R-HSA-182923, Reactome:R-HSA-182940]

organism-modification


PR:000026223
E3 ubiquitin-protein ligase CBL isoform 1 phosphorylated 1 (human)
hCBL/iso:1/Phos:1
"An E3 ubiquitin-protein ligase CBL isoform 1 phosphorylated 1 in human. UniProtKB:P22681-1, Tyr-371, MOD:00048." [PMID:11997497, PMID:15117950, PRO:CNx]