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Protein Ontology report - cyclin-dependent kinase 1 isoform 1
PR:000026179 - http://purl.obolibrary.org/obo/PR_000026179
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000026179   
  PRO namecyclin-dependent kinase 1 isoform 1 
  Synonyms
PRO-Short-label: EXACT:CDK1/iso:1
  Definition"A cyclin-dependent kinase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06493-1 or a 1:1 ortholog thereof." [PRO:CNx] 
  PRO Categorysequence 
  ParentPR:000003271 cyclin-dependent kinase 1
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification4                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000026179
cyclin-dependent kinase 1 isoform 1
CDK1/iso:1
"A cyclin-dependent kinase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06493-1 or a 1:1 ortholog thereof." [PRO:CNx]

organism-sequence


PR:P06493-1
cyclin-dependent kinase 1 isoform 1 (human)
hCDK1/iso:1
"A cyclin-dependent kinase 1 isoform 1 that is encoded in the genome of human." [PRO:CNx]

organism-modification


PR:000026181
cyclin-dependent kinase 1 isoform 1 phosphorylated 1 (human)
hCDK1/iso:1/Phos:1
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 1 in human. UniProtKB:P06493-1, Thr-14, MOD:00047." [PRO:CNA]

Yes
organism-modification


PR:000026211
cyclin-dependent kinase 1 isoform 1 phosphorylated 2 (human)
hCDK1/iso:1/Phos:2
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 2 in human. UniProtKB:P06493-1, Thr-161, MOD:00047." [PRO:CNx, Reactome:R-HSA-157415, Reactome:R-HSA-170066]

Yes
organism-modification


PR:000027123
cyclin-dependent kinase 1 isoform 1 phosphorylated 3 (human)
hCDK1/iso:1/Phos:3
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 3 in human. UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047." [PRO:DAN, Reactome:R-HSA-170078]

Yes
organism-modification


PR:000027124
cyclin-dependent kinase 1 isoform 1 phosphorylated 4 (human)
hCDK1/iso:1/Phos:4
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 4 in human. UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047|Tyr-15, MOD:00048." [PRO:DAN, Reactome:R-HSA-170071, Reactome:R-HSA-170074]

Yes
organism-sequence


PR:P11440-1
cyclin-dependent kinase 1 isoform 1 (mouse)
mCDK1/iso:1
"A cyclin-dependent kinase 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNx]

organism-modification


PR:000026212
cyclin-dependent kinase 1 isoform 1 phosphorylated 2 (mouse)
mCDK1/iso:1/Phos:2
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 2 in mouse. UniProtKB:P11440-1, Thr-161, MOD:00047." [PMID:17242355]

organism-modification


PR:000026213
cyclin-dependent kinase 1 isoform 1 phosphorylated 1 (mouse)
mCDK1/iso:1/Phos:1
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 1 in mouse. UniProtKB:P11440-1, Thr-14, MOD:00047." [PMID:17242355]

modification


PR:000026180
cyclin-dependent kinase 1 isoform 1 phosphorylated 1
CDK1/iso:1/Phos:1
"A cyclin-dependent kinase 1 isoform 1 that has been phosphorylated on a Thr residue within the N-terminal nucleotide binding region. This modification inactivates the kinase. Example: UniProtKB:P06493-1, Thr-14, MOD:00047." [PRO:CNA]

Yes
organism-modification


PR:000026181
cyclin-dependent kinase 1 isoform 1 phosphorylated 1 (human)
hCDK1/iso:1/Phos:1
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 1 in human. UniProtKB:P06493-1, Thr-14, MOD:00047." [PRO:CNA]

Yes
organism-modification


PR:000026213
cyclin-dependent kinase 1 isoform 1 phosphorylated 1 (mouse)
mCDK1/iso:1/Phos:1
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 1 in mouse. UniProtKB:P11440-1, Thr-14, MOD:00047." [PMID:17242355]

modification


PR:000026182
cyclin-dependent kinase 1 isoform 1 phosphorylated 2
CDK1/iso:1/Phos:2
"A cyclin-dependent kinase 1 isoform 1 that has been post-translationally modified to include a phosphorylated Thr residue at the position equivalent to Thr-161 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Thr-161, MOD:00047." [PRO:CNx]

Yes
organism-modification


PR:000026211
cyclin-dependent kinase 1 isoform 1 phosphorylated 2 (human)
hCDK1/iso:1/Phos:2
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 2 in human. UniProtKB:P06493-1, Thr-161, MOD:00047." [PRO:CNx, Reactome:R-HSA-157415, Reactome:R-HSA-170066]

Yes
organism-modification


PR:000026212
cyclin-dependent kinase 1 isoform 1 phosphorylated 2 (mouse)
mCDK1/iso:1/Phos:2
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 2 in mouse. UniProtKB:P11440-1, Thr-161, MOD:00047." [PMID:17242355]

modification


PR:000027121
cyclin-dependent kinase 1 isoform 1 phosphorylated 3
CDK1/iso:1/Phos:3
"A cyclin-dependent kinase 1 isoform 1 that has been phosphorylated at positions equivalent to Thr-14 and Thr-161 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047." [PRO:DAN, Reactome:R-HSA-170078, Reactome:R-HSA-170291]

Yes
organism-modification


PR:000027123
cyclin-dependent kinase 1 isoform 1 phosphorylated 3 (human)
hCDK1/iso:1/Phos:3
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 3 in human. UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047." [PRO:DAN, Reactome:R-HSA-170078]

Yes
modification


PR:000027122
cyclin-dependent kinase 1 isoform 1 phosphorylated 4
CDK1/iso:1/Phos:4
"A cyclin-dependent kinase 1 isoform 1 that has been phosphorylated at positions equivalent to Thr-14, Tyr-15, and Thr-161 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047|Tyr-15, MOD:00048." [PRO:DAN, Reactome:R-HSA-170071, Reactome:R-HSA-170074]

Yes
organism-modification


PR:000027124
cyclin-dependent kinase 1 isoform 1 phosphorylated 4 (human)
hCDK1/iso:1/Phos:4
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 4 in human. UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047|Tyr-15, MOD:00048." [PRO:DAN, Reactome:R-HSA-170071, Reactome:R-HSA-170074]

Yes
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CDK1/iso:1 forms found in complexes   

CDK1/iso:1 Component
 Complexes
PR:000026180 CDK1/iso:1/Phos:1 PR:000027133 cyclin B1:Cdk1 complex phosphorylated 1
PR:000026181 hCDK1/iso:1/Phos:1 PR:000027143 cyclin B1:Cdk1 complex phosphorylated 1 (human)
PR:000026182 CDK1/iso:1/Phos:2 PR:000027134 cyclin B1:Cdk1 complex phosphorylated 2
PR:000027137 cyclin B1:Cdk1 complex phosphorylated 5
PR:000027138 cyclin B2:Cdk1 complex phosphorylated 1
PR:000026211 hCDK1/iso:1/Phos:2 PR:000027144 cyclin B1:Cdk1 complex phosphorylated 2 (human)
PR:000027147 cyclin B1:Cdk1 complex phosphorylated 5 (human)
PR:000027148 cyclin B2:Cdk1 complex phosphorylated 1 (human)
PR:000027121 CDK1/iso:1/Phos:3 PR:000027135 cyclin B1:Cdk1 complex phosphorylated 3
PR:000027139 cyclin B2:Cdk1 complex phosphorylated 2
PR:000027122 CDK1/iso:1/Phos:4 PR:000027136 cyclin B1:Cdk1 complex phosphorylated 4
PR:000027123 hCDK1/iso:1/Phos:3 PR:000027145 cyclin B1:Cdk1 complex phosphorylated 3 (human)
PR:000027149 cyclin B2:Cdk1 complex phosphorylated 2 (human)
PR:000027124 hCDK1/iso:1/Phos:4 PR:000027146 cyclin B1:Cdk1 complex phosphorylated 4 (human)