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family
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PR:000026126 |
eukaryotic serine palmitoyltransferase
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fam:euk-SPT
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"A PLP-dependent alpha-oxoamine synthase that is involved in sphingolipid biosynthesis in Eukaryota, particularly in the condensation of L-serine and palmitoyl-CoA." [PMID:12782147, PRO:CNA]
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gene
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PR:000015596 |
serine palmitoyltransferase 1
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SPTLC1
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"A eukaryotic serine palmitoyltransferase that is a translation product of the human SPTLC1 gene or a 1:1 ortholog thereof." [PRO:CNA]
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organism-gene
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PR:D4A2H2 |
serine palmitoyltransferase 1 (rat)
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rSPTLC1
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"A serine palmitoyltransferase 1 that is encoded in the genome of rat." [OMA:D4A2H2, PRO:DNx]
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organism-gene
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PR:O15269 |
serine palmitoyltransferase 1 (human)
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hSPTLC1
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"A serine palmitoyltransferase 1 that is encoded in the genome of human." [PRO:CNA]
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Yes |
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organism-sequence
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PR:O15269-1 |
serine palmitoyltransferase 1 isoform 1 (human)
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hSPTLC1/iso:1
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"A serine palmitoyltransferase 1 isoform 1 that is encoded in the genome of human." [PRO:HJD]
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organism-sequence
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PR:O15269-2 |
serine palmitoyltransferase 1 isoform h2 (human)
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hSPTLC1/iso:h2
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"A serine palmitoyltransferase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15269-2." [PRO:DNx, UniProtKB:O15269]
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organism-modification
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PR:000045580 |
serine palmitoyltransferase 1 phosphorylated 1 (human)
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hSPTLC1/Phos:1
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"A serine palmitoyltransferase 1 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-164 of the amino acid sequence represented by UniProtKB:O15269-1. Example: UniProtKB:O15269-1, Tyr-164, MOD:00048." [iPTMnet:O15269, PMID:23629659]
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organism-modification
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PR:000061744 |
serine palmitoyltransferase 1 pyridoxal phosphate lysine-containing form (human)
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hSPTLC1/PyrdoxLys+
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"A serine palmitoyltransferase 1 (human) that includes at least one pyridoxal phosphate lysine. UniProtKB:O15269, MOD:00128." [PRO:DNx, Reactome:R-HSA-428155]
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organism-modification
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PR:000075626 |
serine palmitoyltransferase 1 cysteinylated 1 (human)
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hSPTLC1/Cyst:1
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"A serine palmitoyltransferase 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-192 of the amino acid sequence represented by UniProtKB:O15269-1. Example: UniProtKB:O15269-1, Cys-192, MOD:00765." [IEDB_epitope:1057443, PRO:DNx]
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organism-modification
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PR:000078051 |
serine palmitoyltransferase 1 methylated 1 (human)
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hSPTLC1/Me:1
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"A serine palmitoyltransferase 1 (human) that has been methylated on the residue at the position equivalent to Cys-192 of the amino acid sequence represented by UniProtKB:O15269-1. Example: UniProtKB:O15269-1, Cys-192, MOD:00660." [IEDB_epitope:1057444, PRO:DNx]
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organism-gene
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PR:O35704 |
serine palmitoyltransferase 1 (mouse)
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mSPTLC1
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"A serine palmitoyltransferase 1 that is encoded in the genome of mouse." [OMA:O35704, PRO:HJD]
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Yes |
Yes |
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organism-sequence
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PR:O35704-1 |
serine palmitoyltransferase 1 isoform 1 (mouse)
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mSPTLC1/iso:1
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"A serine palmitoyltransferase 1 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]
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Yes |
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organism-gene
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PR:O59682 |
serine palmitoyltransferase 1 (Schizosaccharomyces pombe 972h-)
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Spom972h-SPTLC1
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"A serine palmitoyltransferase 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O59682, PRO:DNx]
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organism-gene
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PR:P25045 |
serine palmitoyltransferase 1 (yeast)
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ySPTLC1
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"A serine palmitoyltransferase 1 that is encoded in the genome of yeast." [OMA:P25045, PRO:DNx]
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organism-gene
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PR:P91079 |
serine palmitoyltransferase 1 (worm)
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SPTLC1 (worm)
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"A serine palmitoyltransferase 1 that is encoded in the genome of worm." [OMA:P91079, PRO:DNx]
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organism-gene
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PR:Q55FL5 |
serine palmitoyltransferase 1 (Dictyostelium discoideum)
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Dicty-SPTLC1
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"A serine palmitoyltransferase 1 that is encoded in the genome of Dictyostelium discoideum." [OMA:Q55FL5, PRO:DNx]
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organism-gene
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PR:Q94IB8 |
long chain base biosynthesis protein 1 (Arabidopsis thaliana)
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At-SPTLC1
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"A serine palmitoyltransferase 1 that is encoded in the genome of Arabidopsis thaliana." [OMA:Q94IB8, PRO:DNx]
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sequence
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PR:000022019 |
serine palmitoyltransferase 1 isoform 1
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SPTLC1/iso:1
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"A serine palmitoyltransferase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35704-1 or a 1:1 ortholog thereof." [PMID:9363775, PRO:HJD]
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organism-sequence
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PR:O15269-1 |
serine palmitoyltransferase 1 isoform 1 (human)
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hSPTLC1/iso:1
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"A serine palmitoyltransferase 1 isoform 1 that is encoded in the genome of human." [PRO:HJD]
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organism-sequence
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PR:O35704-1 |
serine palmitoyltransferase 1 isoform 1 (mouse)
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mSPTLC1/iso:1
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"A serine palmitoyltransferase 1 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]
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Yes |
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gene
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PR:000015597 |
serine palmitoyltransferase 2
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SPTLC2
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"A eukaryotic serine palmitoyltransferase that is a translation product of the human SPTLC2 gene or a 1:1 ortholog thereof." [PRO:CNA]
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organism-gene
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PR:O15270 |
serine palmitoyltransferase 2 (human)
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hSPTLC2
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"A serine palmitoyltransferase 2 that is encoded in the genome of human." [PRO:CNA]
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Yes |
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organism-sequence
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PR:O15270-1 |
serine palmitoyltransferase 2 isoform 1 (human)
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hSPTLC2/iso:1
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"A serine palmitoyltransferase 2 isoform 1 that is encoded in the genome of human." [PRO:HJD]
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organism-modification
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PR:000049342 |
serine palmitoyltransferase 2 pyridoxal phosphate lysine-containing 1 (human)
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hSPTLC2/Pyrdox:1
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"A serine palmitoyltransferase 2 (human) that has been post-translationally modified to include pyridoxal phosphate lysine at position 379 of the amino acid sequence represented by UniProtKB:O15270. UniProtKB:O15270, Lys-379, MOD:00128." [PRO:DNx, Reactome:R-HSA-428146]
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organism-modification
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PR:000073274 |
serine palmitoyltransferase 2 methylated 1 (human)
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hSPTLC2/Me:1
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"A serine palmitoyltransferase 2 (human) that has been methylated on the residue at the position equivalent to Cys-139 of the amino acid sequence represented by UniProtKB:O15270. UniProtKB:O15270, Cys-139, MOD:00660." [IEDB_epitope:1044187, PRO:DNx]
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organism-modification
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PR:000083083 |
serine palmitoyltransferase 2 methylated 2 (human)
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hSPTLC2/Me:2
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"A serine palmitoyltransferase 2 (human) that has been methylated on the residue at the position equivalent to Cys-204 of the amino acid sequence represented by UniProtKB:O15270. UniProtKB:O15270, Cys-204, MOD:00660." [IEDB_epitope:1016968, PRO:DNx]
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organism-gene
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PR:P97363 |
serine palmitoyltransferase 2 (mouse)
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mSPTLC2
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"A serine palmitoyltransferase 2 that is encoded in the genome of mouse." [OMA:P97363, PRO:HJD]
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Yes |
Yes |
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organism-sequence
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PR:P97363-1 |
serine palmitoyltransferase 2 isoform 1 (mouse)
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mSPTLC2/iso:1
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"A serine palmitoyltransferase 2 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]
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Yes |
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organism-gene
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PR:Q3B7D2 |
serine palmitoyltransferase 2 (rat)
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rSPTLC2
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"A serine palmitoyltransferase 2 that is encoded in the genome of rat." [OMA:Q3B7D2, PRO:DNx]
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sequence
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PR:000022020 |
serine palmitoyltransferase 2 isoform 1
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SPTLC2/iso:1
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"A serine palmitoyltransferase 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97363-1 or a 1:1 ortholog thereof." [PMID:8921873, PRO:HJD]
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organism-sequence
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PR:O15270-1 |
serine palmitoyltransferase 2 isoform 1 (human)
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hSPTLC2/iso:1
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"A serine palmitoyltransferase 2 isoform 1 that is encoded in the genome of human." [PRO:HJD]
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organism-sequence
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PR:P97363-1 |
serine palmitoyltransferase 2 isoform 1 (mouse)
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mSPTLC2/iso:1
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"A serine palmitoyltransferase 2 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]
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Yes |
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gene
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PR:000015598 |
serine palmitoyltransferase 3
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SPTLC3
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"A eukaryotic serine palmitoyltransferase that is a translation product of the human SPTLC3 gene or a 1:1 ortholog thereof." [PRO:CNA]
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organism-gene
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PR:Q8BG54 |
serine palmitoyltransferase 3 (mouse)
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mSPTLC3
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"A serine palmitoyltransferase 3 that is encoded in the genome of mouse." [OMA:Q8BG54, PRO:HJD]
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Yes |
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organism-gene
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PR:Q9NUV7 |
serine palmitoyltransferase 3 (human)
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hSPTLC3
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"A serine palmitoyltransferase 3 that is encoded in the genome of human." [PRO:CNA]
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Yes |
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organism-sequence
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PR:Q9NUV7-1 |
serine palmitoyltransferase 3 isoform h1 (human)
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hSPTLC3/iso:h1
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"A serine palmitoyltransferase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NUV7-1." [PRO:DNx, UniProtKB:Q9NUV7]
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organism-sequence
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PR:Q9NUV7-2 |
serine palmitoyltransferase 3 isoform h2 (human)
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hSPTLC3/iso:h2
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"A serine palmitoyltransferase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NUV7-2." [PRO:DNx, UniProtKB:Q9NUV7]
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organism-modification
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PR:000049343 |
serine palmitoyltransferase 3 pyridoxal phosphate lysine-containing 1 (human)
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hSPTLC3/Pyrdox:1
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"A serine palmitoyltransferase 3 (human) that has been post-translationally modified to include pyridoxal phosphate lysine at position 371 of the amino acid sequence represented by UniProtKB:Q9NUV7. UniProtKB:Q9NUV7, Lys-371, MOD:00128." [PRO:DNx, Reactome:R-HSA-428162]
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