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Protein Ontology report - 5-aminolevulinate synthase
PR:000026125 - http://purl.obolibrary.org/obo/PR_000026125
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000026125   
  PRO name5-aminolevulinate synthase 
  Synonyms
Other: EXACT:5-aminolevulinic acid synthase | ALAS
  Definition"A PLP-dependent alpha-oxoamine synthase whose functional form is the first enzyme in the pathway for synthesis of all tetrapyrroles in non-photosynthetic eukaryotes and alpha-proteobacteria. ALAS catalyzes the decarboxylative condensation of glycine and succinyl-CoA, yielding 5-aminolevulinic acid, free coenzyme-A and CO2." [PMID:13598764, PRO:CNA] 
  PRO Categoryfamily 
  ParentPR:000026124 PLP-dependent alpha-oxoamine synthase
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene2                                                  Organism-Gene 11                                        
         Sequence2                                                  Organism-Sequence 10                                        
         Modification2                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF000444
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000026125 5-aminolevulinate synthase
hMCCC2/var:MCCB IVS3+5G->T

gene


PR:000003916 5-aminolevulinate synthase, non-specific, mitochondrial
ALAS1

organism-gene


PR:P07997 5-aminolevulinate synthase, non-specific, mitochondrial (chicken)
chick-ALAS1

organism-gene


PR:P13195 5-aminolevulinate synthase, non-specific, mitochondrial (rat)
rALAS1

organism-sequence


PR:P13195-1 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 (rat)
rALAS1/iso:1

organism-gene


PR:P13196 5-aminolevulinate synthase, non-specific, mitochondrial (human)
hALAS1

organism-sequence


PR:P13196-1 5-aminolevulinate synthase, non-specific, mitochondrial isoform h1 (human)
hALAS1/iso:h1

organism-sequence


PR:P13196-2 5-aminolevulinate synthase, non-specific, mitochondrial isoform h2 (human)
hALAS1/iso:h2

organism-modification


PR:000046304 5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed form (human)
hALAS1/TransPep-

organism-modification


PR:000046305 5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine-containing form (human)
hALAS1/TransPep-/PyrdoxLys+

organism-modification


PR:000046305 5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine-containing form (human)
hALAS1/TransPep-/PyrdoxLys+

organism-modification


PR:000066761 5-aminolevulinate synthase, non-specific, mitochondrial methylated 1 (human)
hALAS1/Me:1

organism-modification


PR:000078022 5-aminolevulinate synthase, non-specific, mitochondrial methylated 2 (human)
hALAS1/Me:2

organism-gene


PR:Q8VC19 5-aminolevulinate synthase, non-specific, mitochondrial (mouse)
mALAS1

organism-sequence


PR:Q8VC19-1 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 (mouse)
mALAS1/iso:1

sequence


PR:000042113 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1
ALAS1/iso:1

organism-sequence


PR:P13195-1 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 (rat)
rALAS1/iso:1

organism-sequence


PR:Q8VC19-1 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 (mouse)
mALAS1/iso:1

modification


PR:000018945 5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed form
ALAS1/TransPep-

organism-modification


PR:000046304 5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed form (human)
hALAS1/TransPep-

organism-modification


PR:000046305 5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine-containing form (human)
hALAS1/TransPep-/PyrdoxLys+

gene


PR:000003917 5-aminolevulinate synthase, erythroid-specific, mitochondrial
ALAS2

organism-gene


PR:O14092 5-aminolevulinate synthase, mitochondrial (Schizosaccharomyces pombe 972h-)
Spom972h-ALAS2

organism-gene


PR:P08680 5-aminolevulinate synthase, erythroid-specific, mitochondrial (mouse)
mALAS2

organism-sequence


PR:P08680-1 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (mouse)
mALAS2/iso:1

organism-gene


PR:P09950 5-aminolevulinate synthase, mitochondrial (yeast)
yALAS2

organism-gene


PR:P22557 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human)
hALAS2

organism-sequence


PR:P22557-1 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (human)
hALAS2/iso:1

organism-sequence


PR:P22557-2 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform h2 (human)
hALAS2/iso:h2

organism-sequence


PR:P22557-3 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform h3 (human)
hALAS2/iso:h3

organism-sequence


PR:P22557-4 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform h4 (human)
hALAS2/iso:h4

organism-modification


PR:000046306 5-aminolevulinate synthase, erythroid-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine-containing form (human)
hALAS2/TransPep-/PyrdoxLys+

organism-modification


PR:000085991 5-aminolevulinate synthase, erythroid-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine-containing 1 (human)
hALAS2/TransPep-/Pyrdox:1

organism-gene


PR:Q54UX3 5-aminolevulinate synthase (Dictyostelium discoideum)
Dicty-ALAS2

organism-gene


PR:Q63147 5-aminolevulinate synthase, erythroid-specific, mitochondrial (rat)
rALAS2

organism-sequence


PR:Q63147-1 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (rat)
rALAS2/iso:1

organism-gene


PR:Q9YHT4 5-aminolevulinate synthase, erythroid-specific, mitochondrial (zebrafish)
z-ALAS2

sequence


PR:000039074 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1
ALAS2/iso:1

organism-sequence


PR:P08680-1 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (mouse)
mALAS2/iso:1

organism-sequence


PR:P22557-1 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (human)
hALAS2/iso:1

organism-sequence


PR:Q63147-1 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (rat)
rALAS2/iso:1

modification


PR:000018947 5-aminolevulinate synthase, erythroid-specific, mitochondrial, transit peptide removed form
ALAS2/TransPep-

organism-modification


PR:000046306 5-aminolevulinate synthase, erythroid-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine-containing form (human)
hALAS2/TransPep-/PyrdoxLys+

organism-modification


PR:000085991 5-aminolevulinate synthase, erythroid-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine-containing 1 (human)
hALAS2/TransPep-/Pyrdox:1