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 |
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family
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|
PR:000026124 |
PLP-dependent alpha-oxoamine synthase
|
hMCCC2/var:MCCB IVS3+5G->T
|
"A protein that consist of a single copy of the Aminotransferase class I and II (Pfam:PF00155) domain. Alpha-oxoamine synthase corresponds to the alpha-division of pyridoxal-5'-phosphate (PLP)-dependent enzymes. Alpha-oxoamine synthase are involved in catalysis of the decarboxylative condensation of a carboxylic acid coenzyme A (CoA) thioester and an amino acid, with the amino acid being covalently bound to the PLP via a Schiff base at the beginning of the catalytic cycle." [PMID:15189147, PMID:17559874, PRO:CNA]
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gene
|
|
PR:000007885 |
2-amino-3-ketobutyrate coenzyme A ligase
|
GCAT
|
"A PLP-dependent alpha-oxoamine synthase that is a translation product of the human GCAT gene or a 1:1 ortholog thereof." [PRO:CNA]
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organism-gene
|
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PR:O75600 |
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (human)
|
hGCAT
|
"A 2-amino-3-ketobutyrate coenzyme A ligase that is encoded in the genome of human." [PRO:CNA, UniProtKB:O75600]
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organism-sequence
|
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PR:O75600-1 |
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial isoform h1 (human)
|
hGCAT/iso:h1
|
"A 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75600-1." [PRO:DNx, UniProtKB:O75600]
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organism-sequence
|
|
PR:O75600-2 |
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial isoform h2 (human)
|
hGCAT/iso:h2
|
"A 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75600-2." [PRO:DNx, UniProtKB:O75600]
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organism-modification
|
|
PR:000047515 |
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial, transit peptide removed form (human)
|
hGCAT/TransPep-
|
"A 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (human) that has had the transit peptide removed. UniProtKB:O75600, 22-419." [PRO:DNx, UniProtKB:O75600]
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organism-modification
|
|
PR:000061492 |
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial, transit peptide removed pyridoxal phosphate lysine-containing 1 (human)
|
hGCAT/TransPep-/Pyrdox:1
|
"A 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (human) that has had the transit peptide removed and that has been pyridoxal phosphate modified on the residue at the position equivalent to Lys-265 of the amino acid sequence represented by UniProtKB:O75600-1. Example: UniProtKB:O75600-1, 22-419, Lys-265, MOD:00128." [PRO:DNx, Reactome:R-HSA-535614]
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organism-gene
|
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PR:O88986 |
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (mouse)
|
mGCAT
|
"A 2-amino-3-ketobutyrate coenzyme A ligase that is encoded in the genome of mouse." [OMA:O88986, PRO:DNx]
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organism-gene
|
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PR:P0AB77 |
2-amino-3-ketobutyrate coenzyme A ligase (Escherichia coli K-12)
|
Ec-GCAT
|
"A 2-amino-3-ketobutyrate coenzyme A ligase that is encoded in the genome of Escherichia coli K-12." [OMA:P0AB77, PRO:DNx]
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organism-gene
|
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PR:Q22768 |
T25B9.1 protein (worm)
|
GCAT (worm)
|
"A 2-amino-3-ketobutyrate coenzyme A ligase that is encoded in the genome of worm." [PANTHER:PTHR13693:SF14, PRO:DNx]
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gene
|
|
PR:000022225 |
8-amino-7-oxononanoate synthase
|
bioF
|
"A PLP-dependent alpha-oxoamine synthase that is a translation product of the Escherichia coli K-12 bioF gene or a 1:1 ortholog thereof." [PMID:10642176, PMID:9813126, PRO:CNA]
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organism-gene
|
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PR:P12998 |
8-amino-7-oxononanoate synthase (Escherichia coli K-12)
|
Ec-bioF
|
"An 8-amino-7-oxononanoate synthase that is encoded in the genome of Escherichia coli K-12." [PRO:CNA, UniProtKB:P12998]
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organism-gene
|
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PR:Q9XVI6 |
serine palmitoyltransferase 3 (worm)
|
bioF (worm)
|
"An 8-amino-7-oxononanoate synthase that is encoded in the genome of worm." [OMA:Q9XVI6, PRO:DNx]
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organism-sequence
|
|
PR:Q9XVI6-1 |
serine palmitoyltransferase 3 isoform a (worm)
|
bioF/iso:a (worm)
|
"A serine palmitoyltransferase 3 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9XVI6-1." [PRO:DNx, UniProtKB:Q9XVI6]
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organism-sequence
|
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PR:Q9XVI6-2 |
serine palmitoyltransferase 3 isoform b (worm)
|
bioF/iso:b (worm)
|
"A serine palmitoyltransferase 3 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9XVI6-2." [PRO:DNx, UniProtKB:Q9XVI6]
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modification
|
|
PR:000024311 |
8-amino-7-oxononanoate synthase, initiator methionine removed form
|
bioF/InitMet-
|
"An 8-amino-7-oxononanoate synthase that has had the initiator methionine removed." [PRO:DNx]
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family
|
|
PR:000026125 |
5-aminolevulinate synthase
|
hMCCC2/var:MCCB IVS3+5G->T
|
"A PLP-dependent alpha-oxoamine synthase whose functional form is the first enzyme in the pathway for synthesis of all tetrapyrroles in non-photosynthetic eukaryotes and alpha-proteobacteria. ALAS catalyzes the decarboxylative condensation of glycine and succinyl-CoA, yielding 5-aminolevulinic acid, free coenzyme-A and CO2." [PMID:13598764, PRO:CNA]
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gene
|
|
PR:000003916 |
5-aminolevulinate synthase, non-specific, mitochondrial
|
ALAS1
|
"A 5-aminolevulinate synthase that is a translation product of the human ALAS1 gene or a 1:1 ortholog thereof." [PRO:CNA]
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organism-gene
|
|
PR:P07997 |
5-aminolevulinate synthase, non-specific, mitochondrial (chicken)
|
chick-ALAS1
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial that is encoded in the genome of chicken." [OMA:P07997, PRO:DNx]
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| | |
organism-gene
|
|
PR:P13195 |
5-aminolevulinate synthase, non-specific, mitochondrial (rat)
|
rALAS1
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial that is encoded in the genome of rat." [OMA:P13195, PRO:DNx]
|
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organism-sequence
|
|
PR:P13195-1 |
5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 (rat)
|
rALAS1/iso:1
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 that is encoded in the genome of rat." [PRO:DNx]
|
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| | |
organism-gene
|
|
PR:P13196 |
5-aminolevulinate synthase, non-specific, mitochondrial (human)
|
hALAS1
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial that is encoded in the genome of human." [PRO:CNA, UniProtKB:P13196]
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|
organism-sequence
|
|
PR:P13196-1 |
5-aminolevulinate synthase, non-specific, mitochondrial isoform h1 (human)
|
hALAS1/iso:h1
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P13196-1." [PRO:DNx, UniProtKB:P13196]
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|
organism-sequence
|
|
PR:P13196-2 |
5-aminolevulinate synthase, non-specific, mitochondrial isoform h2 (human)
|
hALAS1/iso:h2
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P13196-2." [PRO:DNx, UniProtKB:P13196]
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|
organism-modification
|
|
PR:000046304 |
5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed form (human)
|
hALAS1/TransPep-
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial (human) that has had the transit peptide removed. UniProtKB:P13196, 57-640." [PRO:DNx, Reactome:R-HSA-189438]
|
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organism-modification
|
|
PR:000046305 |
5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine-containing form (human)
|
hALAS1/TransPep-/PyrdoxLys+
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial (human) that has had the transit peptide removed and that includes at least one pyridoxal phosphate lysine. UniProtKB:P13196, 57-640, MOD:00128." [PRO:DNx, Reactome:R-HSA-1022086]
|
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|
organism-modification
|
|
PR:000046305 |
5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine-containing form (human)
|
hALAS1/TransPep-/PyrdoxLys+
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial (human) that has had the transit peptide removed and that includes at least one pyridoxal phosphate lysine. UniProtKB:P13196, 57-640, MOD:00128." [PRO:DNx, Reactome:R-HSA-1022086]
|
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|
organism-modification
|
|
PR:000066761 |
5-aminolevulinate synthase, non-specific, mitochondrial methylated 1 (human)
|
hALAS1/Me:1
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial (human) that has been methylated on the residue at the position equivalent to Cys-330 of the amino acid sequence represented by UniProtKB:P13196-1. Example: UniProtKB:P13196-1, Cys-330, MOD:00660." [IEDB_epitope:1025520, IEDB_epitope:999994, PRO:DNx]
|
|
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| | | | | | | | | | |
|
organism-modification
|
|
PR:000078022 |
5-aminolevulinate synthase, non-specific, mitochondrial methylated 2 (human)
|
hALAS1/Me:2
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial (human) that has been methylated on the residue at the position equivalent to Cys-544 of the amino acid sequence represented by UniProtKB:P13196-1. Example: UniProtKB:P13196-1, Cys-544, MOD:00660." [IEDB_epitope:1009891, PRO:DNx]
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| | |
organism-gene
|
|
PR:Q8VC19 |
5-aminolevulinate synthase, non-specific, mitochondrial (mouse)
|
mALAS1
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial that is encoded in the genome of mouse." [OMA:Q8VC19, PRO:DNx]
|
|
|
|
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|
organism-sequence
|
|
PR:Q8VC19-1 |
5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 (mouse)
|
mALAS1/iso:1
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
|
|
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| | | | | | | | |
| | |
sequence
|
|
PR:000042113 |
5-aminolevulinate synthase, non-specific, mitochondrial isoform 1
|
ALAS1/iso:1
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8VC19-1 or a 1:1 ortholog thereof." [PRO:DNx]
|
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|
organism-sequence
|
|
PR:P13195-1 |
5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 (rat)
|
rALAS1/iso:1
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 that is encoded in the genome of rat." [PRO:DNx]
|
|
|
|
|
|
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| | | | | | | | | | |
|
organism-sequence
|
|
PR:Q8VC19-1 |
5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 (mouse)
|
mALAS1/iso:1
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
|
|
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| | | | | | | | |
| | |
modification
|
|
PR:000018945 |
5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed form
|
ALAS1/TransPep-
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial that has had the transit peptide removed." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000046304 |
5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed form (human)
|
hALAS1/TransPep-
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial (human) that has had the transit peptide removed. UniProtKB:P13196, 57-640." [PRO:DNx, Reactome:R-HSA-189438]
|
|
|
|
|
|
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| | | | | | | | | | | | |
organism-modification
|
|
PR:000046305 |
5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine-containing form (human)
|
hALAS1/TransPep-/PyrdoxLys+
|
"A 5-aminolevulinate synthase, non-specific, mitochondrial (human) that has had the transit peptide removed and that includes at least one pyridoxal phosphate lysine. UniProtKB:P13196, 57-640, MOD:00128." [PRO:DNx, Reactome:R-HSA-1022086]
|
|
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| | | | |
gene
|
|
PR:000003917 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial
|
ALAS2
|
"A 5-aminolevulinate synthase that is a translation product of the human ALAS2 gene or a 1:1 ortholog thereof." [PRO:CNA]
|
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| | |
organism-gene
|
|
PR:O14092 |
5-aminolevulinate synthase, mitochondrial (Schizosaccharomyces pombe 972h-)
|
Spom972h-ALAS2
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O14092, PRO:DNx]
|
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| | |
organism-gene
|
|
PR:P08680 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial (mouse)
|
mALAS2
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that is encoded in the genome of mouse." [OMA:P08680, PRO:DNx]
|
|
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|
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| | | | | | | | | | |
|
organism-sequence
|
|
PR:P08680-1 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (mouse)
|
mALAS2/iso:1
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
|
|
|
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| | |
organism-gene
|
|
PR:P09950 |
5-aminolevulinate synthase, mitochondrial (yeast)
|
yALAS2
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that is encoded in the genome of yeast." [OMA:P09950, PRO:DNx]
|
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| | | | | | | | |
| | |
organism-gene
|
|
PR:P22557 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial (human)
|
hALAS2
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that is encoded in the genome of human." [PRO:CNA, UniProtKB:P22557]
|
|
|
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|
|
|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:P22557-1 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (human)
|
hALAS2/iso:1
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 that is encoded in the genome of human." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:P22557-2 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform h2 (human)
|
hALAS2/iso:h2
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22557-2." [PRO:DNx, UniProtKB:P22557]
|
|
|
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|
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|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:P22557-3 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform h3 (human)
|
hALAS2/iso:h3
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22557-3." [PRO:DNx, UniProtKB:P22557]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:P22557-4 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform h4 (human)
|
hALAS2/iso:h4
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22557-4." [PRO:DNx, UniProtKB:P22557]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000046306 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine-containing form (human)
|
hALAS2/TransPep-/PyrdoxLys+
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human) that has had the transit peptide removed and that includes at least one pyridoxal phosphate lysine. UniProtKB:P22557, 50-587, MOD:00128." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000085991 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine-containing 1 (human)
|
hALAS2/TransPep-/Pyrdox:1
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human) that has had the transit peptide removed and that has been pyridoxal phosphate modified on the residue at the position equivalent to Lys-391 of the amino acid sequence represented by UniProtKB:P22557-1. Example: UniProtKB:P22557-1, 50-587, Lys-391, MOD:00128." [PRO:DNx, Reactome:R-HSA-1022083]
|
|
|
|
|
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|
| | | | | | | | |
| | |
organism-gene
|
|
PR:Q54UX3 |
5-aminolevulinate synthase (Dictyostelium discoideum)
|
Dicty-ALAS2
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that is encoded in the genome of Dictyostelium discoideum." [PANTHER:PTHR13693:SF7, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-gene
|
|
PR:Q63147 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial (rat)
|
rALAS2
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that is encoded in the genome of rat." [OMA:Q63147, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:Q63147-1 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (rat)
|
rALAS2/iso:1
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 that is encoded in the genome of rat." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-gene
|
|
PR:Q9YHT4 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial (zebrafish)
|
z-ALAS2
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that is encoded in the genome of zebrafish." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
sequence
|
|
PR:000039074 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1
|
ALAS2/iso:1
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22557-1 or a 1:1 ortholog thereof." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:P08680-1 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (mouse)
|
mALAS2/iso:1
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:P22557-1 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (human)
|
hALAS2/iso:1
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 that is encoded in the genome of human." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:Q63147-1 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (rat)
|
rALAS2/iso:1
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 that is encoded in the genome of rat." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000018947 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial, transit peptide removed form
|
ALAS2/TransPep-
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial that has had the transit peptide removed." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000046306 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine-containing form (human)
|
hALAS2/TransPep-/PyrdoxLys+
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human) that has had the transit peptide removed and that includes at least one pyridoxal phosphate lysine. UniProtKB:P22557, 50-587, MOD:00128." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000085991 |
5-aminolevulinate synthase, erythroid-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine-containing 1 (human)
|
hALAS2/TransPep-/Pyrdox:1
|
"A 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human) that has had the transit peptide removed and that has been pyridoxal phosphate modified on the residue at the position equivalent to Lys-391 of the amino acid sequence represented by UniProtKB:P22557-1. Example: UniProtKB:P22557-1, 50-587, Lys-391, MOD:00128." [PRO:DNx, Reactome:R-HSA-1022083]
|
|
|
|
|
|
|
| | | | |
| | | | | | |
family
|
|
PR:000026126 |
eukaryotic serine palmitoyltransferase
|
fam:euk-SPT
|
"A PLP-dependent alpha-oxoamine synthase that is involved in sphingolipid biosynthesis in Eukaryota, particularly in the condensation of L-serine and palmitoyl-CoA." [PMID:12782147, PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
gene
|
|
PR:000015596 |
serine palmitoyltransferase 1
|
SPTLC1
|
"A eukaryotic serine palmitoyltransferase that is a translation product of the human SPTLC1 gene or a 1:1 ortholog thereof." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-gene
|
|
PR:D4A2H2 |
serine palmitoyltransferase 1 (rat)
|
rSPTLC1
|
"A serine palmitoyltransferase 1 that is encoded in the genome of rat." [OMA:D4A2H2, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-gene
|
|
PR:O15269 |
serine palmitoyltransferase 1 (human)
|
hSPTLC1
|
"A serine palmitoyltransferase 1 that is encoded in the genome of human." [PRO:CNA]
|
|
Yes |
|
|
|
|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:O15269-1 |
serine palmitoyltransferase 1 isoform 1 (human)
|
hSPTLC1/iso:1
|
"A serine palmitoyltransferase 1 isoform 1 that is encoded in the genome of human." [PRO:HJD]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:O15269-2 |
serine palmitoyltransferase 1 isoform h2 (human)
|
hSPTLC1/iso:h2
|
"A serine palmitoyltransferase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15269-2." [PRO:DNx, UniProtKB:O15269]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000045580 |
serine palmitoyltransferase 1 phosphorylated 1 (human)
|
hSPTLC1/Phos:1
|
"A serine palmitoyltransferase 1 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-164 of the amino acid sequence represented by UniProtKB:O15269-1. Example: UniProtKB:O15269-1, Tyr-164, MOD:00048." [iPTMnet:O15269, PMID:23629659]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000061744 |
serine palmitoyltransferase 1 pyridoxal phosphate lysine-containing form (human)
|
hSPTLC1/PyrdoxLys+
|
"A serine palmitoyltransferase 1 (human) that includes at least one pyridoxal phosphate lysine. UniProtKB:O15269, MOD:00128." [PRO:DNx, Reactome:R-HSA-428155]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000075626 |
serine palmitoyltransferase 1 cysteinylated 1 (human)
|
hSPTLC1/Cyst:1
|
"A serine palmitoyltransferase 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-192 of the amino acid sequence represented by UniProtKB:O15269-1. Example: UniProtKB:O15269-1, Cys-192, MOD:00765." [IEDB_epitope:1057443, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000078051 |
serine palmitoyltransferase 1 methylated 1 (human)
|
hSPTLC1/Me:1
|
"A serine palmitoyltransferase 1 (human) that has been methylated on the residue at the position equivalent to Cys-192 of the amino acid sequence represented by UniProtKB:O15269-1. Example: UniProtKB:O15269-1, Cys-192, MOD:00660." [IEDB_epitope:1057444, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-gene
|
|
PR:O35704 |
serine palmitoyltransferase 1 (mouse)
|
mSPTLC1
|
"A serine palmitoyltransferase 1 that is encoded in the genome of mouse." [OMA:O35704, PRO:HJD]
|
Yes |
Yes |
|
|
|
|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:O35704-1 |
serine palmitoyltransferase 1 isoform 1 (mouse)
|
mSPTLC1/iso:1
|
"A serine palmitoyltransferase 1 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-gene
|
|
PR:O59682 |
serine palmitoyltransferase 1 (Schizosaccharomyces pombe 972h-)
|
Spom972h-SPTLC1
|
"A serine palmitoyltransferase 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O59682, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-gene
|
|
PR:P25045 |
serine palmitoyltransferase 1 (yeast)
|
ySPTLC1
|
"A serine palmitoyltransferase 1 that is encoded in the genome of yeast." [OMA:P25045, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-gene
|
|
PR:P91079 |
serine palmitoyltransferase 1 (worm)
|
SPTLC1 (worm)
|
"A serine palmitoyltransferase 1 that is encoded in the genome of worm." [OMA:P91079, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-gene
|
|
PR:Q55FL5 |
serine palmitoyltransferase 1 (Dictyostelium discoideum)
|
Dicty-SPTLC1
|
"A serine palmitoyltransferase 1 that is encoded in the genome of Dictyostelium discoideum." [OMA:Q55FL5, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-gene
|
|
PR:Q94IB8 |
long chain base biosynthesis protein 1 (Arabidopsis thaliana)
|
At-SPTLC1
|
"A serine palmitoyltransferase 1 that is encoded in the genome of Arabidopsis thaliana." [OMA:Q94IB8, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
sequence
|
|
PR:000022019 |
serine palmitoyltransferase 1 isoform 1
|
SPTLC1/iso:1
|
"A serine palmitoyltransferase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35704-1 or a 1:1 ortholog thereof." [PMID:9363775, PRO:HJD]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:O15269-1 |
serine palmitoyltransferase 1 isoform 1 (human)
|
hSPTLC1/iso:1
|
"A serine palmitoyltransferase 1 isoform 1 that is encoded in the genome of human." [PRO:HJD]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:O35704-1 |
serine palmitoyltransferase 1 isoform 1 (mouse)
|
mSPTLC1/iso:1
|
"A serine palmitoyltransferase 1 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
gene
|
|
PR:000015597 |
serine palmitoyltransferase 2
|
SPTLC2
|
"A eukaryotic serine palmitoyltransferase that is a translation product of the human SPTLC2 gene or a 1:1 ortholog thereof." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-gene
|
|
PR:O15270 |
serine palmitoyltransferase 2 (human)
|
hSPTLC2
|
"A serine palmitoyltransferase 2 that is encoded in the genome of human." [PRO:CNA]
|
|
Yes |
|
|
|
|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:O15270-1 |
serine palmitoyltransferase 2 isoform 1 (human)
|
hSPTLC2/iso:1
|
"A serine palmitoyltransferase 2 isoform 1 that is encoded in the genome of human." [PRO:HJD]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000049342 |
serine palmitoyltransferase 2 pyridoxal phosphate lysine-containing 1 (human)
|
hSPTLC2/Pyrdox:1
|
"A serine palmitoyltransferase 2 (human) that has been post-translationally modified to include pyridoxal phosphate lysine at position 379 of the amino acid sequence represented by UniProtKB:O15270. UniProtKB:O15270, Lys-379, MOD:00128." [PRO:DNx, Reactome:R-HSA-428146]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000073274 |
serine palmitoyltransferase 2 methylated 1 (human)
|
hSPTLC2/Me:1
|
"A serine palmitoyltransferase 2 (human) that has been methylated on the residue at the position equivalent to Cys-139 of the amino acid sequence represented by UniProtKB:O15270. UniProtKB:O15270, Cys-139, MOD:00660." [IEDB_epitope:1044187, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000083083 |
serine palmitoyltransferase 2 methylated 2 (human)
|
hSPTLC2/Me:2
|
"A serine palmitoyltransferase 2 (human) that has been methylated on the residue at the position equivalent to Cys-204 of the amino acid sequence represented by UniProtKB:O15270. UniProtKB:O15270, Cys-204, MOD:00660." [IEDB_epitope:1016968, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-gene
|
|
PR:P97363 |
serine palmitoyltransferase 2 (mouse)
|
mSPTLC2
|
"A serine palmitoyltransferase 2 that is encoded in the genome of mouse." [OMA:P97363, PRO:HJD]
|
Yes |
Yes |
|
|
|
|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:P97363-1 |
serine palmitoyltransferase 2 isoform 1 (mouse)
|
mSPTLC2/iso:1
|
"A serine palmitoyltransferase 2 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-gene
|
|
PR:Q3B7D2 |
serine palmitoyltransferase 2 (rat)
|
rSPTLC2
|
"A serine palmitoyltransferase 2 that is encoded in the genome of rat." [OMA:Q3B7D2, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
sequence
|
|
PR:000022020 |
serine palmitoyltransferase 2 isoform 1
|
SPTLC2/iso:1
|
"A serine palmitoyltransferase 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97363-1 or a 1:1 ortholog thereof." [PMID:8921873, PRO:HJD]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:O15270-1 |
serine palmitoyltransferase 2 isoform 1 (human)
|
hSPTLC2/iso:1
|
"A serine palmitoyltransferase 2 isoform 1 that is encoded in the genome of human." [PRO:HJD]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:P97363-1 |
serine palmitoyltransferase 2 isoform 1 (mouse)
|
mSPTLC2/iso:1
|
"A serine palmitoyltransferase 2 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
gene
|
|
PR:000015598 |
serine palmitoyltransferase 3
|
SPTLC3
|
"A eukaryotic serine palmitoyltransferase that is a translation product of the human SPTLC3 gene or a 1:1 ortholog thereof." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-gene
|
|
PR:Q8BG54 |
serine palmitoyltransferase 3 (mouse)
|
mSPTLC3
|
"A serine palmitoyltransferase 3 that is encoded in the genome of mouse." [OMA:Q8BG54, PRO:HJD]
|
|
Yes |
|
|
|
|
| | | | | | | | |
| | |
organism-gene
|
|
PR:Q9NUV7 |
serine palmitoyltransferase 3 (human)
|
hSPTLC3
|
"A serine palmitoyltransferase 3 that is encoded in the genome of human." [PRO:CNA]
|
|
Yes |
|
|
|
|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:Q9NUV7-1 |
serine palmitoyltransferase 3 isoform h1 (human)
|
hSPTLC3/iso:h1
|
"A serine palmitoyltransferase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NUV7-1." [PRO:DNx, UniProtKB:Q9NUV7]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-sequence
|
|
PR:Q9NUV7-2 |
serine palmitoyltransferase 3 isoform h2 (human)
|
hSPTLC3/iso:h2
|
"A serine palmitoyltransferase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NUV7-2." [PRO:DNx, UniProtKB:Q9NUV7]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000049343 |
serine palmitoyltransferase 3 pyridoxal phosphate lysine-containing 1 (human)
|
hSPTLC3/Pyrdox:1
|
"A serine palmitoyltransferase 3 (human) that has been post-translationally modified to include pyridoxal phosphate lysine at position 371 of the amino acid sequence represented by UniProtKB:Q9NUV7. UniProtKB:Q9NUV7, Lys-371, MOD:00128." [PRO:DNx, Reactome:R-HSA-428162]
|
|
|
|
|
|
|
| | | | |
| | | | | | |
gene
|
|
PR:000026127 |
bacterial-type serine palmitoyltransferase
|
spt1
|
"A PLP-dependent alpha-oxoamine synthase that is a translation product of the Sphingomonas paucimobilis spt1 gene or a 1:1 ortholog thereof." [PMID:17559874, PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:A5VD79 |
serine palmitoyltransferase (Rhizorhabdus wittichii RW1)
|
spt1 (RHIWR)
|
"A bacterial-type serine palmitoyltransferase that is encoded in the genome of Rhizorhabdus wittichii RW1." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:A5VD79-1 |
bacterial-type serine palmitoyltransferase isoform 1 (Rhizorhabdus wittichii RW1)
|
spt1/iso:1 (RHIWR)
|
"A bacterial-type serine palmitoyltransferase isoform 1 that is encoded in the genome of Rhizorhabdus wittichii RW1." [PMID:20578000, PRO:CNA]
|
|
Yes |
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:A7BFV6 |
serine palmitoyltransferase (Sphingobacterium multivorum)
|
spt1 (SPHMU)
|
"A bacterial-type serine palmitoyltransferase that is encoded in the genome of Sphingobacterium multivorum." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:A7BFV6-1 |
serine palmitoyltransferase isoform 1 (Sphingobacterium multivorum)
|
spt1/iso:1 (SPHMU)
|
"A bacterial-type serine palmitoyltransferase isoform 1 that is encoded in the genome of Sphingobacterium multivorum." [PMID:17557831, PRO:CNA]
|
|
Yes |
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:Q93UV0 |
serine palmitoyltransferase (Sphingomonas paucimobilis)
|
spt1 (SPHPI)
|
"A bacterial-type serine palmitoyltransferase that is encoded in the genome of Sphingomonas paucimobilis." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:Q93UV0-1 |
bacterial-type serine palmitoyltransferase isoform 1 (Sphingomonas paucimobilis)
|
spt1/iso:1 (SPHPI)
|
"A bacterial-type serine palmitoyltransferase isoform 1 that is encoded in the genome of Sphingomonas paucimobilis." [PMID:17559874, PRO:CNA]
|
|
Yes |
|
|
|
|
| | | | | | |
| | | | |
sequence
|
|
PR:000026128 |
bacterial-type serine palmitoyltransferase isoform 1
|
spt1/iso:1
|
"A bacterial-type serine palmitoyltransferase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q93UV0-1 or a 1:1 ortholog thereof." [PMID:17559874, PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:A5VD79-1 |
bacterial-type serine palmitoyltransferase isoform 1 (Rhizorhabdus wittichii RW1)
|
spt1/iso:1 (RHIWR)
|
"A bacterial-type serine palmitoyltransferase isoform 1 that is encoded in the genome of Rhizorhabdus wittichii RW1." [PMID:20578000, PRO:CNA]
|
|
Yes |
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:A7BFV6-1 |
serine palmitoyltransferase isoform 1 (Sphingobacterium multivorum)
|
spt1/iso:1 (SPHMU)
|
"A bacterial-type serine palmitoyltransferase isoform 1 that is encoded in the genome of Sphingobacterium multivorum." [PMID:17557831, PRO:CNA]
|
|
Yes |
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:Q93UV0-1 |
bacterial-type serine palmitoyltransferase isoform 1 (Sphingomonas paucimobilis)
|
spt1/iso:1 (SPHPI)
|
"A bacterial-type serine palmitoyltransferase isoform 1 that is encoded in the genome of Sphingomonas paucimobilis." [PMID:17559874, PRO:CNA]
|
|
Yes |
|
|
