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family
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PR:000025824 |
Axin
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fam:axin
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"A protein that contains a copy of the Regulator of G protein signaling domain (Pfam:PF00615), followed by a copy of the Axin beta-catenin binding domain (Pfam:PF08833) and a C-terminal copy of the DIX domain (Pfam:PF00778). Axins play key roles in WNT signalling." [PMID:15067197, PMID:17404597, PMID:19909509, PRO:CNA]
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gene
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PR:000004526 |
Axin-1
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AXIN1
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"An Axin that is a translation product of the human AXIN1 gene or a 1:1 ortholog thereof." [PRO:DNx]
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organism-gene
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PR:O15169 |
Axin-1 (human)
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hAXIN1
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"An Axin-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O15169]
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organism-sequence
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PR:000060464 |
Axin-1 sequence variant W247* (human)
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hAXIN1/var:W247*
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"An Axin-1 (human) that has has been truncated after the position equivalent to Glu-246 of the amino acid sequence represented by UniProtKB:O15169-1. Example: UniProtKB:O15169-1, 1-246." [PRO:DNx, Reactome:R-HSA-5251512]
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organism-sequence
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PR:000061379 |
Axin-1 sequence variant Y346* (human)
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hAXIN1/var:Y346*
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"An Axin-1 (human) that has has been truncated after the position equivalent to Pro-345 of the amino acid sequence represented by UniProtKB:O15169-1. Example: UniProtKB:O15169-1, 1-345." [PRO:DNx, Reactome:R-HSA-4839753]
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organism-sequence
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PR:000062109 |
Axin-1 sequence variant E406* (human)
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hAXIN1/var:E406*
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"An Axin-1 (human) that has has been truncated after the position equivalent to Ala-405 of the amino acid sequence represented by UniProtKB:O15169-1. Example: UniProtKB:O15169-1, 1-405." [PRO:DNx, Reactome:R-HSA-5251500]
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organism-sequence
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PR:000063020 |
Axin-1 sequence variant L396M (human)
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hAXIN1/var:L396M
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"An Axin-1 (human) that has a Met residue at the position equivalent to Leu-396 of the amino acid sequence represented by UniProtKB:O15169-1. Example: UniProtKB:O15169-1, Leu-396, CHEBI:16044." [PRO:DNx, Reactome:R-HSA-5251503]
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organism-sequence
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PR:000063515 |
Axin-1 sequence variant E255S (human)
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hAXIN1/var:E255S
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"An Axin-1 (human) that has a Ser residue at the position equivalent to Glu-255 of the amino acid sequence represented by UniProtKB:O15169-1. Example: UniProtKB:O15169-1, Glu-255, CHEBI:29999." [PRO:DNx, Reactome:R-HSA-5251505]
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organism-sequence
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PR:000063568 |
Axin-1 sequence variant R354L (human)
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hAXIN1/var:R354L
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"An Axin-1 (human) that has a Leu residue at the position equivalent to Arg-354 of the amino acid sequence represented by UniProtKB:O15169-1. Example: UniProtKB:O15169-1, Arg-354, CHEBI:30006." [PRO:DNx, Reactome:R-HSA-5251511]
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organism-sequence
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PR:O15169-1 |
Axin-1 isoform 1 (human)
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hAXIN1/iso:1
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"An Axin-1 isoform 1 that is encoded in the genome of human." [PMID:9230313, PRO:CNA]
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Yes |
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organism-sequence
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PR:O15169-2 |
Axin-1 isoform 2 (human)
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hAXIN1/iso:2
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"An Axin-1 isoform 2 that is encoded in the genome of human." [PRO:CNA]
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organism-modification
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PR:000046442 |
Axin-1 ADP-ribosylated form (human)
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hAXIN1/ADPribRes+
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"An Axin-1 (human) that includes at least one ADP-ribosylated residue. UniProtKB:O15169, MOD:00752." [PRO:DNx, Reactome:R-HSA-3640841]
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organism-modification
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PR:000046443 |
Axin-1 ADP-ribosylated and ubiquitinated form (human)
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hAXIN1/ADPribUbiq+
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"An Axin-1 (human) that includes at least one ADP-ribosylated residue and at least one ubiquitinated lysine. UniProtKB:O15169, MOD:00752|MOD:01148." [PRO:DNx, Reactome:R-HSA-3640864]
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organism-modification
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PR:000046443 |
Axin-1 ADP-ribosylated and ubiquitinated form (human)
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hAXIN1/ADPribUbiq+
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"An Axin-1 (human) that includes at least one ADP-ribosylated residue and at least one ubiquitinated lysine. UniProtKB:O15169, MOD:00752|MOD:01148." [PRO:DNx, Reactome:R-HSA-3640864]
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organism-modification
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PR:000046444 |
Axin-1 phosphorylated 1 (human)
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hAXIN1/Phos:1
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"An Axin-1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-481, and phosphoserine at positions 486 and 493 of the amino acid sequence represented by UniProtKB:O15169. UniProtKB:O15169, Thr-481, MOD:00047|Ser-486/Ser-493, MOD:00046." [PRO:DAN, Reactome:R-HSA-206040]
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organism-modification
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PR:000046445 |
Axin-1 ubiquitinated 1 (human)
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hAXIN1/Ubiq:1
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"An Axin-1 (human) that has been ubiquitinated on the residue at the position equivalent to Lys-501 of the amino acid sequence represented by UniProtKB:O15169. UniProtKB:O15169, Lys-501, MOD:01148." [PRO:DAN, Reactome:R-HSA-4641133]
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organism-gene
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PR:O35625 |
Axin-1 (mouse)
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mAXIN1
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"An Axin-1 that is encoded in the genome of mouse." [OMA:O35625, PRO:DNx]
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organism-sequence
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PR:O35625-1 |
Axin-1 isoform 1 (mouse)
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mAXIN1/iso:1
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"An Axin-1 isoform 1 that is encoded in the genome of mouse." [PMID:9230313, PRO:HJD]
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Yes |
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organism-sequence
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PR:O35625-2 |
Axin-1 isoform 2 (mouse)
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mAXIN1/iso:2
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"An Axin-1 isoform 2 that is encoded in the genome of mouse." [PMID:9230313, PRO:HJD]
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organism-gene
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PR:O42400 |
Axin-1 (chicken)
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chick-AXIN1
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"An Axin-1 that is encoded in the genome of chicken." [OMA:O42400, PRO:DNx]
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organism-gene
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PR:O70239 |
Axin-1 (rat)
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rAXIN1
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"An Axin-1 that is encoded in the genome of rat." [PRO:DNx]
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organism-sequence
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PR:O70239-1 |
Axin-1 isoform 2 (rat)
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rAXIN1/iso:2
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"An Axin-1 isoform 2 that is encoded in the genome of rat." [PMID:9482734, PRO:CNA]
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organism-gene
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PR:P57094 |
Axin-1 (zebrafish)
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z-AXIN1
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"An Axin-1 that is encoded in the genome of zebrafish." [PRO:DNx]
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organism-gene
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PR:Q9V407 |
Axin (fruit fly)
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fly-AXIN1
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"An Axin-1 that is encoded in the genome of fruit fly." [OMA:Q9V407, PRO:DNx]
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sequence
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PR:000025825 |
Axin-1 isoform 1
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AXIN1/iso:1
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"An Axin-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35625-1 or a 1:1 ortholog thereof." [PRO:CNA]
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organism-sequence
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PR:O15169-1 |
Axin-1 isoform 1 (human)
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hAXIN1/iso:1
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"An Axin-1 isoform 1 that is encoded in the genome of human." [PMID:9230313, PRO:CNA]
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Yes |
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organism-sequence
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PR:O35625-1 |
Axin-1 isoform 1 (mouse)
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mAXIN1/iso:1
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"An Axin-1 isoform 1 that is encoded in the genome of mouse." [PMID:9230313, PRO:HJD]
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Yes |
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sequence
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PR:000025826 |
Axin-1 isoform 2
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AXIN1/iso:2
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"An Axin-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35625-2 or a 1:1 ortholog thereof." [PRO:CNA]
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organism-sequence
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PR:O15169-2 |
Axin-1 isoform 2 (human)
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hAXIN1/iso:2
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"An Axin-1 isoform 2 that is encoded in the genome of human." [PRO:CNA]
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organism-sequence
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PR:O35625-2 |
Axin-1 isoform 2 (mouse)
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mAXIN1/iso:2
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"An Axin-1 isoform 2 that is encoded in the genome of mouse." [PMID:9230313, PRO:HJD]
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organism-sequence
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PR:O70239-1 |
Axin-1 isoform 2 (rat)
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rAXIN1/iso:2
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"An Axin-1 isoform 2 that is encoded in the genome of rat." [PMID:9482734, PRO:CNA]
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gene
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PR:000004527 |
Axin-2
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AXIN2
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"An Axin that is a translation product of the human AXIN2 gene or a 1:1 ortholog thereof." [PRO:DNx]
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organism-gene
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PR:O70240 |
Axin-2 (rat)
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rAXIN2
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"An Axin-2 that is encoded in the genome of rat." [OMA:O70240, PRO:DNx]
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organism-gene
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PR:O88566 |
Axin-2 (mouse)
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mAXIN2
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"An Axin-2 that is encoded in the genome of mouse." [OMA:O88566, PRO:DNx]
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organism-gene
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PR:P57095 |
Axin-2 (zebrafish)
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z-AXIN2
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"An Axin-2 that is encoded in the genome of zebrafish." [OMA:P57095, PRO:DNx]
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organism-gene
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PR:Q9Y2T1 |
Axin-2 (human)
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hAXIN2
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"An Axin-2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9Y2T1]
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organism-modification
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PR:000046446 |
Axin-2 ADP-ribosylated form (human)
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hAXIN2/ADPribRes+
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"An Axin-2 (human) that includes at least one ADP-ribosylated residue. UniProtKB:Q9Y2T1, MOD:00752." [PRO:DNx, Reactome:R-HSA-3640842]
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organism-modification
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PR:000046447 |
Axin-2 ADP-ribosylated and ubiquitinated form (human)
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hAXIN2/ADPribUbiq+
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"An Axin-2 (human) that includes at least one ADP-ribosylated residue and at least one ubiquitinated lysine. UniProtKB:Q9Y2T1, MOD:00752|MOD:01148." [PRO:DNx, Reactome:R-HSA-3640859]
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organism-modification
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PR:000046447 |
Axin-2 ADP-ribosylated and ubiquitinated form (human)
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hAXIN2/ADPribUbiq+
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"An Axin-2 (human) that includes at least one ADP-ribosylated residue and at least one ubiquitinated lysine. UniProtKB:Q9Y2T1, MOD:00752|MOD:01148." [PRO:DNx, Reactome:R-HSA-3640859]
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organism-modification
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PR:000066095 |
Axin-2 phosphorylated 1 (human)
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hAXIN2/Phos:1
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"An Axin-2 (human) that has been phosphorylated on the residue at the position equivalent to Thr-826 of the amino acid sequence represented by UniProtKB:Q9Y2T1. UniProtKB:Q9Y2T1, Thr-826, MOD:00047." [IEDB_epitope:2149697, PRO:DNx]
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organism-gene
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PR:Q9YGY0 |
Axin-1 (frog)
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frog-axin
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"An Axin that is a translation product of the axin1 gene in frog." [PRO:DAN]
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