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Protein Ontology report - eukaryotic translation initiation factor 3 subunit F isoform 1
PR:000025798 - http://purl.obolibrary.org/obo/PR_000025798
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000025798   
  PRO nameeukaryotic translation initiation factor 3 subunit F isoform 1 
  Synonyms
PRO-Short-label: EXACT:EIF3F/iso:1
  Definition"A eukaryotic translation initiation factor 3 subunit F that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00303-1 or a 1:1 ortholog thereof." [PMID:16141072, PMID:9341143] 
  PRO Categorysequence 
  ParentPR:000006978 eukaryotic translation initiation factor 3 subunit F
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000025798 eukaryotic translation initiation factor 3 subunit F isoform 1
EIF3F/iso:1

organism-sequence


PR:O00303-1 eukaryotic translation initiation factor 3 subunit F isoform 1 (human)
hEIF3F/iso:1

organism-modification


PR:000025800 eukaryotic translation initiation factor 3 subunit F isoform 1 CDK11-phosphorylated 1 (human)
hEIF3F/iso:1/Phos:1
Yes
organism-modification


PR:000025839 eukaryotic translation initiation factor 3 subunit F isoform 1 unmodified form (human)
hEIF3F/iso:1/UnMod

organism-sequence


PR:Q9DCH4-1 eukaryotic translation initiation factor 3 subunit F isoform 1 (mouse)
mEIF3F/iso:1

modification


PR:000025799 eukaryotic translation initiation factor 3 subunit F isoform 1 CDK11-phosphorylated form
EIF3F/iso:1/Phos:1

organism-modification


PR:000025800 eukaryotic translation initiation factor 3 subunit F isoform 1 CDK11-phosphorylated 1 (human)
hEIF3F/iso:1/Phos:1
Yes
modification


PR:000025838 eukaryotic translation initiation factor 3 subunit F isoform 1 unmodified form
EIF3F/iso:1/UnMod

organism-modification


PR:000025839 eukaryotic translation initiation factor 3 subunit F isoform 1 unmodified form (human)
hEIF3F/iso:1/UnMod

modification


PR:000026572 eukaryotic translation initiation factor 3 subunit F isoform 1, initiator methionine removed form
EIF3F/iso:1/InitMet-

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000025800 hEIF3F/iso:1/Phos:1
UniProtKB:O00303-1, Ser-46, MOD:00046|Thr-119, MOD:00047		 acts_upstream_of_or_withinGO:0017148 negative regulation of translation PMID:19245811
GO:0043065 positive regulation of apoptotic process PMID:19245811
enablesincreased GO:0031369 translation initiation factor binding with PR:P55884 eIF-3-eta (human) PMID:19245811
located_inGO:0005852 eukaryotic translation initiation factor 3 complex PMID:19245811