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Protein Ontology report - MYD88:TIRAP:activated TLR4 receptor
PR:000025784 - http://purl.obolibrary.org/obo/PR_000025784
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000025784   
  PRO nameMYD88:TIRAP:activated TLR4 receptor 
  Synonyms
Other: EXACT:MyD88:Mal complexed with the activated TLR4 receptor | MYD88:Mal:activated TLR4 receptor
  Definition"A MYD88:TIRAP:activated TLR complex whose activated TLR component is TLR4 receptor." [PMID:16751103, PRO:CNA, PRO:DAN, TLR:AMM] 
  CommentRequested by=TLR. 
  PRO Categorycomplex 
  ParentPR:000025774 MYD88:TIRAP:activated TLR complex
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Complex1                                                  Organism-Complex 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
complex


PR:000025784 MYD88:TIRAP:activated TLR4 receptor
h(CD3E:CD3G)

organism-complex


PR:000027174 MYD88s:TIRAP:activated TLR4 receptor (mouse)
mTLR4/iso:1/SigPep-/NGlyco:1
Yes
organism-complex


PR:000027175 MYD88l:TIRAP:activated TLR4 receptor (mouse)
mTLR4/iso:1/SigPep-/NGlyco:1

organism-complex


PR:000037475 MYD88:TIRAP:activated TLR4 receptor (chicken)
chick-(MYD88:TIRAP:TLR4actv)
Yes
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0002755 MyD88-dependent toll-like receptor signaling pathwayPR:000037475 chick-(MYD88:TIRAP:TLR4actv) Reactome:REACT_25089
GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathwayPR:000027174 mTLR4/iso:1/SigPep-/NGlyco:1 PMID:12538665
GO:0034142 toll-like receptor 4 signaling pathwayPR:000037475 chick-(MYD88:TIRAP:TLR4actv) Reactome:REACT_25089

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005886 plasma membranePR:000037475 chick-(MYD88:TIRAP:TLR4actv) Reactome:REACT_26615