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Protein Ontology report - interferon regulatory factor
PR:000025304 - http://purl.obolibrary.org/obo/PR_000025304
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000025304   
  PRO nameinterferon regulatory factor 
  Definition"A protein with core architecture containing a single Interferon regulatory factor transcription factor domain (Pfam:PF00605) in the amino-terminal region." [PRO:DAN] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family3                                                  Organism-Family 0                                        
         Gene9                                                  Organism-Gene 23                                        
         Sequence8                                                  Organism-Sequence 30                                        
         Modification14                                                  Organism-Modification 44                                        
  Term Hierarchy
  Visualization
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000025304

interferon regulatory factor

cheY/iso:1/InitMet-


"A protein with core architecture containing a single Interferon regulatory factor transcription factor domain (Pfam:PF00605) in the amino-terminal region." [PRO:DAN]


family



PR:000001862

interferon regulatory factor 1/2

ICOS


"An interferon regulatory factor with core architecture consisting of a single Interferon regulatory factor transcription factor domain (Pfam:PF00605) in the amino-terminal region, and lacking an Interferon-regulatory factor 3 (Pfam:PF10401) domain." [PRO:WCB]


gene



PR:000002043

interferon regulatory factor 1

IRF1


"An interferon regulatory factor 1/2 that is a translation product of the human IRF1 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:P10914

interferon regulatory factor 1 (human)

hIRF1


"An interferon regulatory factor 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P10914]


organism-modification



PR:000071170

interferon regulatory factor 1 methylated 1 (human)

hIRF1/Me:1


"An interferon regulatory factor 1 (human) that has been methylated on the residue at the position equivalent to Cys-274 of the amino acid sequence represented by UniProtKB:P10914. UniProtKB:P10914, Cys-274, MOD:00660." [IEDB_epitope:1052840, PRO:DNx]


organism-gene



PR:P15314

interferon regulatory factor 1 (mouse)

mIRF1


"An interferon regulatory factor 1 that is encoded in the genome of mouse." [OMA:P15314, PRO:DNx]


organism-gene



PR:P23570

interferon regulatory factor 1 (rat)

rIRF1


"An interferon regulatory factor 1 that is encoded in the genome of rat." [OMA:P23570, PRO:DNx]


organism-gene



PR:Q90876

interferon regulatory factor 1 (chicken)

chick-IRF1


"An interferon regulatory factor 1 that is encoded in the genome of chicken." [OMA:Q90876, PRO:DNx]


gene



PR:000002044

interferon regulatory factor 2

IRF2


"An interferon regulatory factor 1/2 that is a translation product of the human IRF2 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:P14316

interferon regulatory factor 2 (human)

hIRF2


"An interferon regulatory factor 2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P14316]


organism-sequence



PR:P14316-1

interferon regulatory factor 2 isoform 1 (human)

hIRF2/iso:1


"An interferon regulatory factor 2 isoform 1 that is encoded in the genome of human." [PRO:PD]


organism-modification



PR:000028813

interferon regulatory factor 2 isoform 1 acetylated 1 (human)

hIRF2/iso:1/Ac:1


"An interferon regulatory factor 2 isoform 1 acetylated 1 in human. UniProtKB:P14316-1, Lys-75/Lys-78, MOD:00064." [PMID:12738767, PRO:PD]


organism-sequence



PR:P14316-2

interferon regulatory factor 2 isoform h2 (human)

hIRF2/iso:h2


"An interferon regulatory factor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14316-2." [PRO:DNx, UniProtKB:P14316]


organism-modification



PR:000077219

interferon regulatory factor 2 methylated 1 (human)

hIRF2/Me:1


"An interferon regulatory factor 2 (human) that has been methylated on the residue at the position equivalent to Cys-200 of the amino acid sequence represented by UniProtKB:P14316-1. Example: UniProtKB:P14316-1, Cys-200, MOD:00660." [IEDB_epitope:1035928, PRO:DNx]


organism-modification



PR:000081273

interferon regulatory factor 2 deaminated 1 (human)

hIRF2/Deam:1


"An interferon regulatory factor 2 (human) that has been deaminated on the residue at the position equivalent to Asn-80 of the amino acid sequence represented by UniProtKB:P14316-1. Example: UniProtKB:P14316-1, Asn-80, MOD:00684." [IEDB_epitope:1990060, PRO:DNx]


organism-gene



PR:P23906

interferon regulatory factor 2 (mouse)

mIRF2


"An interferon regulatory factor 2 that is encoded in the genome of mouse." [OMA:P23906, PRO:DNx]


organism-gene



PR:Q98925

interferon regulatory factor 2 (chicken)

chick-IRF2


"An interferon regulatory factor 2 that is encoded in the genome of chicken." [OMA:Q98925, PRO:DNx]


sequence



PR:000028810

interferon regulatory factor 2 isoform 1

IRF2/iso:1


"An interferon regulatory factor 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14316-1 or a 1:1 ortholog thereof." [PMID:12738767, PRO:PD]


organism-sequence



PR:P14316-1

interferon regulatory factor 2 isoform 1 (human)

hIRF2/iso:1


"An interferon regulatory factor 2 isoform 1 that is encoded in the genome of human." [PRO:PD]


organism-modification



PR:000028813

interferon regulatory factor 2 isoform 1 acetylated 1 (human)

hIRF2/iso:1/Ac:1


"An interferon regulatory factor 2 isoform 1 acetylated 1 in human. UniProtKB:P14316-1, Lys-75/Lys-78, MOD:00064." [PMID:12738767, PRO:PD]


modification



PR:000028812

interferon regulatory factor 2 isoform 1 acetylated 1

IRF2/iso:1/Ac:1


"An interferon regulatory factor 2 isoform 1 that has been acetylated at the two Lys residues in the motif PKTWKA located in IRF (Pfam:PF00605) domain. Example: UniProtKB:P14316-1, Lys-75/Lys-78, MOD:00064." [PMID:12738767, PRO:PD]


organism-modification



PR:000028813

interferon regulatory factor 2 isoform 1 acetylated 1 (human)

hIRF2/iso:1/Ac:1


"An interferon regulatory factor 2 isoform 1 acetylated 1 in human. UniProtKB:P14316-1, Lys-75/Lys-78, MOD:00064." [PMID:12738767, PRO:PD]


family



PR:000001863

interferon regulatory factor 3-9

ICOS


"An interferon regulatory factor with core architecture consisting of a single Interferon regulatory factor transcription factor domain (Pfam:PF00605) in the amino-terminal region, followed by an Interferon-regulatory factor 3 (Pfam:PF10401) domain." [PRO:WCB]


gene



PR:000002045

interferon regulatory factor 3

IRF3


"An interferon regulatory factor 3-9 that is a translation product of the human IRF3 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:P70671

interferon regulatory factor 3 (mouse)

mIRF3


"An interferon regulatory factor 3 that is encoded in the genome of mouse." [OMA:P70671, PRO:CNA]


organism-sequence



PR:C0IXK2

interferon regulatory factor 3 isoform 2 (mouse)

mIRF3/iso:2


"An interferon regulatory factor 3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:C0IXK2." [PMID:18851954, PRO:HJD]


organism-sequence



PR:P70671-1

interferon regulatory factor 3 isoform 1 (mouse)

mIRF3/iso:1


"An interferon regulatory factor 3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-modification



PR:000027097

interferon regulatory factor 3 isoform 1 phosphorylated 1 (mouse)

mIRF3/iso:1/Phos:1


"An interferon regulatory factor 3 isoform 1 phosphorylated 1 in mouse. UniProtKB:P70671-1, Ser-378/Ser-379, MOD:00046." [PMID:12872135, PRO:CNA]


Yes
organism-gene



PR:Q14653

interferon regulatory factor 3 (human)

hIRF3


"An interferon regulatory factor 3 that is encoded in the genome of human." [PRO:CNA]


Yes
organism-sequence



PR:Q14653-1

interferon regulatory factor 3 isoform 1 (human)

hIRF3/iso:1


"An interferon regulatory factor 3 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000025763

interferon regulatory factor 3 isoform 1 phosphorylated 1 (human)

hIRF3/iso:1/Phos:1


"An interferon regulatory factor 3 isoform 1 phosphorylated 1 in human. UniProtKB:Q14653-1, Ser-385/Ser-386, MOD:00046." [PMID:10805757, PRO:CNA]

Yes

Yes
organism-modification



PR:000045489

interferon regulatory factor 3 isoform 1 phosphorylated 2 (human)

hIRF3/iso:1/Phos:2


"An interferon regulatory factor 3 isoform 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-339 and on Ser and Thr residues within the 5ST site (Ser-396, Ser-398, Ser-402, Thr-404, and Ser-405). UniProtKB:Q14653-1, Ser-339/Ser-396/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047." [PRO:CNA, Reactome:R-HSA-936418]


Yes
organism-sequence



PR:Q14653-2

interferon regulatory factor 3 isoform h2 (human)

hIRF3/iso:h2


"An interferon regulatory factor 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14653-2." [PRO:DNx, UniProtKB:Q14653]


organism-sequence



PR:Q14653-3

interferon regulatory factor 3 isoform h3 (human)

hIRF3/iso:h3


"An interferon regulatory factor 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14653-3." [PRO:DNx, UniProtKB:Q14653]


organism-sequence



PR:Q14653-4

interferon regulatory factor 3 isoform h4 (human)

hIRF3/iso:h4


"An interferon regulatory factor 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14653-4." [PRO:DNx, UniProtKB:Q14653]


organism-sequence



PR:Q14653-5

interferon regulatory factor 3 isoform h5 (human)

hIRF3/iso:h5


"An interferon regulatory factor 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14653-5." [PRO:DNx, UniProtKB:Q14653]


organism-modification



PR:000028702

interferon regulatory factor 3 unmodified form (human)

hIRF3/UnMod


"An interferon regulatory factor 3 unmodified form in human." [PRO:CNA]


Yes
organism-modification



PR:000045488

interferon regulatory factor 3 phosphorylated 1 (human)

hIRF3/Phos:1


"An interferon regulatory factor 3 (human) that has been phosphorylated on residues at positions equivalent to Ser-396, Ser-398, Ser-402, Thr-404, and Ser-405 of the amino acid sequence represented by UniProtKB:Q14653-1. Example: UniProtKB:Q14653-1, Ser-386/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047." [PRO:CNA, PRO:DAN, Reactome:R-HSA-166258, Reactome:R-HSA-177654]


Yes
organism-modification



PR:000065516

interferon regulatory factor 3 methylated 1 (human)

hIRF3/Me:1


"An interferon regulatory factor 3 (human) that has been methylated on the residue at the position equivalent to Met-258 of the amino acid sequence represented by UniProtKB:Q14653-1. Example: UniProtKB:Q14653-1, Met-258, MOD:00716." [IEDB_epitope:431178, PRO:DNx]


organism-modification



PR:000075605

interferon regulatory factor 3 cysteinylated 1 (human)

hIRF3/Cyst:1


"An interferon regulatory factor 3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-167 of the amino acid sequence represented by UniProtKB:Q14653-1. Example: UniProtKB:Q14653-1, Cys-167, MOD:00765." [IEDB_epitope:1562127, PRO:DNx]


sequence



PR:000003257

interferon regulatory factor 3 isoform 1

IRF3/iso:1


"An interferon regulatory factor 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14653-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:P70671-1

interferon regulatory factor 3 isoform 1 (mouse)

mIRF3/iso:1


"An interferon regulatory factor 3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-modification



PR:000027097

interferon regulatory factor 3 isoform 1 phosphorylated 1 (mouse)

mIRF3/iso:1/Phos:1


"An interferon regulatory factor 3 isoform 1 phosphorylated 1 in mouse. UniProtKB:P70671-1, Ser-378/Ser-379, MOD:00046." [PMID:12872135, PRO:CNA]


Yes
organism-sequence



PR:Q14653-1

interferon regulatory factor 3 isoform 1 (human)

hIRF3/iso:1


"An interferon regulatory factor 3 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000025763

interferon regulatory factor 3 isoform 1 phosphorylated 1 (human)

hIRF3/iso:1/Phos:1


"An interferon regulatory factor 3 isoform 1 phosphorylated 1 in human. UniProtKB:Q14653-1, Ser-385/Ser-386, MOD:00046." [PMID:10805757, PRO:CNA]

Yes

Yes
organism-modification



PR:000045489

interferon regulatory factor 3 isoform 1 phosphorylated 2 (human)

hIRF3/iso:1/Phos:2


"An interferon regulatory factor 3 isoform 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-339 and on Ser and Thr residues within the 5ST site (Ser-396, Ser-398, Ser-402, Thr-404, and Ser-405). UniProtKB:Q14653-1, Ser-339/Ser-396/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047." [PRO:CNA, Reactome:R-HSA-936418]


Yes
modification



PR:000003259

interferon regulatory factor 3 isoform 1 phosphorylated form

IRF3/iso:1/PhosRes+


"An interferon regulatory factor 3 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000003260

interferon regulatory factor 3 isoform 1 phosphorylated 1

IRF3/iso:1/Phos:1


"An interferon regulatory factor 3 isoform 1 phosphorylated form in which the phosphorylation occurs upon stimulation by virus infection or treatment with double-stranded RNA or LPS. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit. Example: UniProtKB:Q14653-1, Ser-385/Ser-386, MOD:00046." [PMID:14703513, PMID:20043992, TLR:AMM]


organism-modification



PR:000025763

interferon regulatory factor 3 isoform 1 phosphorylated 1 (human)

hIRF3/iso:1/Phos:1


"An interferon regulatory factor 3 isoform 1 phosphorylated 1 in human. UniProtKB:Q14653-1, Ser-385/Ser-386, MOD:00046." [PMID:10805757, PRO:CNA]

Yes

Yes
organism-modification



PR:000027097

interferon regulatory factor 3 isoform 1 phosphorylated 1 (mouse)

mIRF3/iso:1/Phos:1


"An interferon regulatory factor 3 isoform 1 phosphorylated 1 in mouse. UniProtKB:P70671-1, Ser-378/Ser-379, MOD:00046." [PMID:12872135, PRO:CNA]


Yes
organism-modification



PR:000045489

interferon regulatory factor 3 isoform 1 phosphorylated 2 (human)

hIRF3/iso:1/Phos:2


"An interferon regulatory factor 3 isoform 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-339 and on Ser and Thr residues within the 5ST site (Ser-396, Ser-398, Ser-402, Thr-404, and Ser-405). UniProtKB:Q14653-1, Ser-339/Ser-396/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047." [PRO:CNA, Reactome:R-HSA-936418]


Yes
modification



PR:000028701

interferon regulatory factor 3 unmodified form

IRF3/UnMod


"An interferon regulatory factor 3 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]


organism-modification



PR:000028702

interferon regulatory factor 3 unmodified form (human)

hIRF3/UnMod


"An interferon regulatory factor 3 unmodified form in human." [PRO:CNA]


Yes
gene



PR:000002046

interferon regulatory factor 4

IRF4


"An interferon regulatory factor 3-9 that is a translation product of the human IRF4 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:Q15306

interferon regulatory factor 4 (human)

hIRF4


"An interferon regulatory factor 4 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q15306]


organism-sequence



PR:Q15306-1

interferon regulatory factor 4 isoform h1 (human)

hIRF4/iso:h1


"An interferon regulatory factor 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15306-1." [PRO:DNx, UniProtKB:Q15306]


organism-sequence



PR:Q15306-2

interferon regulatory factor 4 isoform h2 (human)

hIRF4/iso:h2


"An interferon regulatory factor 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15306-2." [PRO:DNx, UniProtKB:Q15306]


organism-modification



PR:000065544

interferon regulatory factor 4 methylated 1 (human)

hIRF4/Me:1


"An interferon regulatory factor 4 (human) that has been methylated on the residue at the position equivalent to Cys-356 of the amino acid sequence represented by UniProtKB:Q15306-1. Example: UniProtKB:Q15306-1, Cys-356, MOD:00660." [IEDB_epitope:1028955, IEDB_epitope:1039497, PRO:DNx]


organism-modification



PR:000070171

interferon regulatory factor 4 deaminated 1 (human)

hIRF4/Deam:1


"An interferon regulatory factor 4 (human) that has been deaminated on the residue at the position equivalent to Gln-26 of the amino acid sequence represented by UniProtKB:Q15306-1. Example: UniProtKB:Q15306-1, Gln-26, MOD:00685." [IEDB_epitope:764623, PRO:DNx]


organism-modification



PR:000073206

interferon regulatory factor 4 methylated 2 (human)

hIRF4/Me:2


"An interferon regulatory factor 4 (human) that has been methylated on the residue at the position equivalent to Cys-250 of the amino acid sequence represented by UniProtKB:Q15306-1. Example: UniProtKB:Q15306-1, Cys-250, MOD:00660." [IEDB_epitope:1000125, PRO:DNx]


organism-modification



PR:000075306

interferon regulatory factor 4 methylated 3 (human)

hIRF4/Me:3


"An interferon regulatory factor 4 (human) that has been methylated on the residue at the position equivalent to Cys-19 of the amino acid sequence represented by UniProtKB:Q15306-1. Example: UniProtKB:Q15306-1, Cys-19, MOD:00660." [IEDB_epitope:1059226, PRO:DNx]


organism-modification



PR:000075783

interferon regulatory factor 4 cysteinylated 1 (human)

hIRF4/Cyst:1


"An interferon regulatory factor 4 (human) that has been cysteinylated on the residue at the position equivalent to Cys-19 of the amino acid sequence represented by UniProtKB:Q15306-1. Example: UniProtKB:Q15306-1, Cys-19, MOD:00765." [IEDB_epitope:932525, PRO:DNx]


organism-modification



PR:000078479

interferon regulatory factor 4 cysteinylated 2 (human)

hIRF4/Cyst:2


"An interferon regulatory factor 4 (human) that has been cysteinylated on the residue at the position equivalent to Cys-356 of the amino acid sequence represented by UniProtKB:Q15306-1. Example: UniProtKB:Q15306-1, Cys-356, MOD:00765." [IEDB_epitope:1028954, PRO:DNx]


organism-modification



PR:000083983

interferon regulatory factor 4 cysteinylated 3 (human)

hIRF4/Cyst:3


"An interferon regulatory factor 4 (human) that has been cysteinylated on the residue at the position equivalent to Cys-250 of the amino acid sequence represented by UniProtKB:Q15306-1. Example: UniProtKB:Q15306-1, Cys-250, MOD:00765." [IEDB_epitope:1561478, PRO:DNx]


organism-modification



PR:000084232

interferon regulatory factor 4 deaminated 2 (human)

hIRF4/Deam:2


"An interferon regulatory factor 4 (human) that has been deaminated on the residue at the position equivalent to Asn-21 of the amino acid sequence represented by UniProtKB:Q15306-1. Example: UniProtKB:Q15306-1, Asn-21, MOD:00684." [IEDB_epitope:764622, PRO:DNx]


organism-gene



PR:Q64287

interferon regulatory factor 4 (mouse)

mIRF4


"An interferon regulatory factor 4 that is encoded in the genome of mouse." [OMA:Q64287, PRO:DNx]


organism-sequence



PR:Q64287-1

interferon regulatory factor 4 isoform m1 (mouse)

mIRF4/iso:m1


"An interferon regulatory factor 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q64287-1." [PRO:DNx, UniProtKB:Q64287]


organism-sequence



PR:Q64287-2

interferon regulatory factor 4 isoform m2 (mouse)

mIRF4/iso:m2


"An interferon regulatory factor 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q64287-2." [PRO:DNx, UniProtKB:Q64287]


gene



PR:000002047

interferon regulatory factor 5

IRF5


"An interferon regulatory factor 3-9 that is a translation product of the human IRF5 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:P56477

interferon regulatory factor 5 (mouse)

mIRF5


"An interferon regulatory factor 5 that is encoded in the genome of mouse." [OMA:P56477, PRO:DNx]


organism-sequence



PR:B2CC69

interferon regulatory factor 5 isoform 2 (mouse)

mIRF5/iso:2


"An interferon regulatory factor 5 isoform 2 that is encoded in the genome of mouse. This isoform contains contains an internal deletion of most of exons 4 to 6 in comparison to isoform 1." [PMID:18332133, PRO:CNA]


organism-modification



PR:000027096

interferon regulatory factor 5 isoform 2 phosphorylated 1 (mouse)

mIRF5/iso:2/Phos:1


"An interferon regulatory factor 5 isoform 2 phosphorylated 1 in mouse." [PMID:18332133, PRO:CNA]


Yes
organism-sequence



PR:P56477-1

interferon regulatory factor 5 isoform 1 (mouse)

mIRF5/iso:1


"An interferon regulatory factor 5 isoform 1 that is encoded in the genome of mouse." [PMID:18332133, PRO:CNA]


organism-modification



PR:000027094

interferon regulatory factor 5 isoform 1 phosphorylated 1 (mouse)

mIRF5/iso:1/Phos:1


"An interferon regulatory factor 5 isoform 1 phosphorylated 1 in mouse." [PMID:18332133, PRO:CNA]


Yes
organism-modification



PR:000027535

interferon regulatory factor 5 isoform 1 K63-polyubiquitinated 1 (mouse)

mIRF5/iso:1/K63polyUbiq:1


"An interferon regulatory factor 5 isoform 1 K63-polyubiquitinated 1 in mouse. UniProtKB:P56477-1, Lys-410/Lys-411, PR:000044772." [PMID:18824541, PRO:CNA, TLR:AMM]


organism-gene



PR:Q13568

interferon regulatory factor 5 (human)

hIRF5


"An interferon regulatory factor 5 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q13568]


organism-sequence



PR:Q13568-1

interferon regulatory factor 5 isoform 1 (human)

hIRF5/iso:1


"An interferon regulatory factor 5 isoform 1 that is encoded in the genome of human." [PMID:15805103, PRO:CNA]


organism-sequence



PR:Q13568-2

interferon regulatory factor 5 isoform h2 (human)

hIRF5/iso:h2


"An interferon regulatory factor 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13568-2." [PRO:DNx, UniProtKB:Q13568]


organism-sequence



PR:Q13568-3

interferon regulatory factor 5 isoform h3 (human)

hIRF5/iso:h3


"An interferon regulatory factor 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13568-3." [PRO:DNx, UniProtKB:Q13568]


organism-sequence



PR:Q13568-4

interferon regulatory factor 5 isoform h4 (human)

hIRF5/iso:h4


"An interferon regulatory factor 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13568-4." [PRO:DNx, UniProtKB:Q13568]


organism-sequence



PR:Q13568-5

interferon regulatory factor 5 isoform h5 (human)

hIRF5/iso:h5


"An interferon regulatory factor 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13568-5." [PRO:DNx, UniProtKB:Q13568]


organism-sequence



PR:Q13568-6

interferon regulatory factor 5 isoform h6 (human)

hIRF5/iso:h6


"An interferon regulatory factor 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13568-6." [PRO:DNx, UniProtKB:Q13568]


organism-modification



PR:000065832

interferon regulatory factor 5 methylated 1 (human)

hIRF5/Me:1


"An interferon regulatory factor 5 (human) that has been methylated on the residue at the position equivalent to Cys-44 of the amino acid sequence represented by UniProtKB:Q13568-1. Example: UniProtKB:Q13568-1, Cys-44, MOD:00660." [IEDB_epitope:1014736, PRO:DNx]


organism-modification



PR:000065856

interferon regulatory factor 5 cysteinylated 1 (human)

hIRF5/Cyst:1


"An interferon regulatory factor 5 (human) that has been cysteinylated on the residue at the position equivalent to Cys-28 of the amino acid sequence represented by UniProtKB:Q13568-1. Example: UniProtKB:Q13568-1, Cys-28, MOD:00765." [IEDB_epitope:1004203, PRO:DNx]


organism-modification



PR:000071639

interferon regulatory factor 5 methylated 2 (human)

hIRF5/Me:2


"An interferon regulatory factor 5 (human) that has been methylated on the residue at the position equivalent to Cys-357 of the amino acid sequence represented by UniProtKB:Q13568-1. Example: UniProtKB:Q13568-1, Cys-357, MOD:00660." [IEDB_epitope:1006130, PRO:DNx]


organism-modification



PR:000075034

interferon regulatory factor 5 methylated 3 (human)

hIRF5/Me:3


"An interferon regulatory factor 5 (human) that has been methylated on the residue at the position equivalent to Cys-272 of the amino acid sequence represented by UniProtKB:Q13568-1. Example: UniProtKB:Q13568-1, Cys-272, MOD:00660." [IEDB_epitope:1022240, IEDB_epitope:1022241, IEDB_epitope:1050429, PRO:DNx]


organism-modification



PR:000079300

interferon regulatory factor 5 citrullinated 1 (human)

hIRF5/Cit:1


"An interferon regulatory factor 5 (human) that has been citrullinated on the residue at the position equivalent to Arg-424 of the amino acid sequence represented by UniProtKB:Q13568-1. Example: UniProtKB:Q13568-1, Arg-424, MOD:00219." [IEDB_epitope:1309057, PRO:DNx]


organism-modification



PR:000081350

interferon regulatory factor 5 cysteinylated 2 (human)

hIRF5/Cyst:2


"An interferon regulatory factor 5 (human) that has been cysteinylated on the residue at the position equivalent to Cys-272 of the amino acid sequence represented by UniProtKB:Q13568-1. Example: UniProtKB:Q13568-1, Cys-272, MOD:00765." [IEDB_epitope:1022239, PRO:DNx]


organism-modification



PR:000085949

interferon regulatory factor 5 phosphorylated 1 (human)

hIRF5/Phos:1


"An interferon regulatory factor 5 (human) that has been phosphorylated on the residue at the position equivalent to Ser-446 of the amino acid sequence represented by UniProtKB:Q13568-1. Example: UniProtKB:Q13568-1, Ser-446, MOD:00046." [PRO:DNx, Reactome:R-HSA-9860271, Reactome:R-HSA-9860304]


organism-gene



PR:Q5ZJM5

uncharacterized protein, RCJMB04_17b14 translation product (chicken)

chick-IRF5


"An interferon regulatory factor 5 that is encoded in the genome of chicken." [PRO:DAN]


sequence



PR:000027087

interferon regulatory factor 5 isoform 1

IRF5/iso:1


"An interferon regulatory factor 5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56477-1 or a 1:1 ortholog thereof." [PMID:18332133, PRO:CNA]


organism-sequence



PR:P56477-1

interferon regulatory factor 5 isoform 1 (mouse)

mIRF5/iso:1


"An interferon regulatory factor 5 isoform 1 that is encoded in the genome of mouse." [PMID:18332133, PRO:CNA]


organism-modification



PR:000027094

interferon regulatory factor 5 isoform 1 phosphorylated 1 (mouse)

mIRF5/iso:1/Phos:1


"An interferon regulatory factor 5 isoform 1 phosphorylated 1 in mouse." [PMID:18332133, PRO:CNA]


Yes
organism-modification



PR:000027535

interferon regulatory factor 5 isoform 1 K63-polyubiquitinated 1 (mouse)

mIRF5/iso:1/K63polyUbiq:1


"An interferon regulatory factor 5 isoform 1 K63-polyubiquitinated 1 in mouse. UniProtKB:P56477-1, Lys-410/Lys-411, PR:000044772." [PMID:18824541, PRO:CNA, TLR:AMM]


organism-sequence



PR:Q13568-1

interferon regulatory factor 5 isoform 1 (human)

hIRF5/iso:1


"An interferon regulatory factor 5 isoform 1 that is encoded in the genome of human." [PMID:15805103, PRO:CNA]


modification



PR:000027093

interferon regulatory factor 5 isoform 1 phosphorylated 1

IRF5/iso:1/Phos:1


"An interferon regulatory factor 5 isoform 1 that has been phosphorylated on Ser residues within the C-terminal region, leading to a conformational change and promoting dimerization." [PMID:18332133, PRO:CNA]


organism-modification



PR:000027094

interferon regulatory factor 5 isoform 1 phosphorylated 1 (mouse)

mIRF5/iso:1/Phos:1


"An interferon regulatory factor 5 isoform 1 phosphorylated 1 in mouse." [PMID:18332133, PRO:CNA]


Yes
modification



PR:000027534

interferon regulatory factor 5 isoform 1 K63-polyubiquitinated 1

IRF5/iso:1/Ubiq:1


"An interferon regulatory factor 5 isoform 1 that has been K63-linked polyubiquitinated in response to TLR/MyD88-dependent signaling. Ubiquitinated by TRAF6. Example: UniProtKB:P56477-1, Lys-410/Lys-411, PR:000044772." [PMID:18824541, PRO:CNA]


organism-modification



PR:000027535

interferon regulatory factor 5 isoform 1 K63-polyubiquitinated 1 (mouse)

mIRF5/iso:1/K63polyUbiq:1


"An interferon regulatory factor 5 isoform 1 K63-polyubiquitinated 1 in mouse. UniProtKB:P56477-1, Lys-410/Lys-411, PR:000044772." [PMID:18824541, PRO:CNA, TLR:AMM]


sequence



PR:000027090

interferon regulatory factor 5 isoform 2

IRF5/iso:2


"An interferon regulatory factor 5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:B2CC69 or a 1:1 ortholog thereof." [PMID:18332133, PRO:CNA]


organism-sequence



PR:B2CC69

interferon regulatory factor 5 isoform 2 (mouse)

mIRF5/iso:2


"An interferon regulatory factor 5 isoform 2 that is encoded in the genome of mouse. This isoform contains contains an internal deletion of most of exons 4 to 6 in comparison to isoform 1." [PMID:18332133, PRO:CNA]


organism-modification



PR:000027096

interferon regulatory factor 5 isoform 2 phosphorylated 1 (mouse)

mIRF5/iso:2/Phos:1


"An interferon regulatory factor 5 isoform 2 phosphorylated 1 in mouse." [PMID:18332133, PRO:CNA]


Yes
modification



PR:000027095

interferon regulatory factor 5 isoform 2 phosphorylated 1

IRF5/iso:2/Phos:1


"An interferon regulatory factor 5 isoform 2 that has been phosphorylated on Ser residues within the C-terminal region, leading to a conformational change and promoting dimerization." [PMID:18332133, PRO:CNA]


organism-modification



PR:000027096

interferon regulatory factor 5 isoform 2 phosphorylated 1 (mouse)

mIRF5/iso:2/Phos:1


"An interferon regulatory factor 5 isoform 2 phosphorylated 1 in mouse." [PMID:18332133, PRO:CNA]


Yes
gene



PR:000002048

interferon regulatory factor 6

IRF6


"An interferon regulatory factor 3-9 that is a translation product of the human IRF6 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:O14896

interferon regulatory factor 6 (human)

hIRF6


"An interferon regulatory factor 6 that is encoded in the genome of human." [PRO:WCB, UniProtKB:O14896]


organism-sequence



PR:O14896-1

interferon regulatory factor 6 isoform 1 (human)

hIRF6/iso:1


"An interferon regulatory factor 6 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:O14896-2

interferon regulatory factor 6 isoform h2 (human)

hIRF6/iso:h2


"An interferon regulatory factor 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14896-2." [PRO:DNx, UniProtKB:O14896]


organism-gene



PR:P97431

interferon regulatory factor 6 (mouse)

mIRF6


"An interferon regulatory factor 6 that is encoded in the genome of mouse." [OMA:P97431, PRO:DNx]


organism-sequence



PR:P97431-1

interferon regulatory factor 6 isoform 1 (mouse)

mIRF6/iso:1


"An interferon regulatory factor 6 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000038013

interferon regulatory factor 6 isoform 1

IRF6/iso:1


"An interferon regulatory factor 6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14896-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:O14896-1

interferon regulatory factor 6 isoform 1 (human)

hIRF6/iso:1


"An interferon regulatory factor 6 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P97431-1

interferon regulatory factor 6 isoform 1 (mouse)

mIRF6/iso:1


"An interferon regulatory factor 6 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


gene



PR:000002049

interferon regulatory factor 7

IRF7


"An interferon regulatory factor 3-9 that is a translation product of the human IRF7 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:P70434

interferon regulatory factor 7 (mouse)

mIRF7


"An interferon regulatory factor 7 that is encoded in the genome of mouse." [OMA:P70434, PRO:CNA]


organism-gene



PR:Q92985

interferon regulatory factor 7 (human)

hIRF7


"An interferon regulatory factor 7 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q92985]


organism-sequence



PR:Q92985-1

interferon regulatory factor 7 isoform A (human)

hIRF7/iso:A


"An interferon regulatory factor 7 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000027082

interferon regulatory factor 7 isoform 1 phosphorylated 1 (human)

hIRF7/iso:1/Phos:1


"An interferon regulatory factor 7 isoform 1 phosphorylated 1 in human. UniProtKB:Q92985-1, Ser-477/Ser-479, MOD:00046." [PMID:10893229, PMID:14517278, TLR:AMM]


Yes
organism-modification



PR:000037791

interferon regulatory factor 7 isoform 1 unphosphorylated 1 (human)

hIRF7/iso:1/UnPhos:1


"An interferon regulatory factor 7 isoform 1 unphosphorylated 1 in human. UniProtKB:Q92985-1, Ser-477/Ser-479, PR:000026291." [PMID:10893229, PMID:14517278, PRO:CNA]

Yes

organism-sequence



PR:Q92985-2

interferon regulatory factor 7 isoform B (human)

hIRF7/iso:B


"An interferon regulatory factor 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92985-2." [PRO:DNx, UniProtKB:Q92985]


organism-sequence



PR:Q92985-3

interferon regulatory factor 7 isoform C (human)

hIRF7/iso:C


"An interferon regulatory factor 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92985-3." [PRO:DNx, UniProtKB:Q92985]


organism-sequence



PR:Q92985-4

interferon regulatory factor 7 isoform D (human)

hIRF7/iso:D


"An interferon regulatory factor 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92985-4." [PRO:DNx, UniProtKB:Q92985]


organism-modification



PR:000028704

interferon regulatory factor 7 unmodified form (human)

hIRF7/UnMod


"An interferon regulatory factor 7 unmodified form in human." [PRO:CNA]


Yes
organism-modification



PR:000048049

interferon regulatory factor 7 phosphorylated 1 (human)

hIRF7/Phos:1


"An interferon regulatory factor 7 (human) that has been post-translationally modified to include phosphoserine at positions 477 and 479 of the amino acid sequence represented by UniProtKB:Q92985. UniProtKB:Q92985, Ser-477/Ser-479, MOD:00046." [PRO:DNx, Reactome:R-HSA-450270, Reactome:R-HSA-450318]


organism-modification



PR:000048050

interferon regulatory factor 7 ubiquitinated form (human)

hIRF7/UbiqLys+


"An interferon regulatory factor 7 (human) that includes at least one ubiquitinated lysine. UniProtKB:Q92985, MOD:01148." [PRO:DNx, Reactome:R-HSA-975154]


organism-modification



PR:000066902

interferon regulatory factor 7 cysteinylated 1 (human)

hIRF7/Cyst:1


"An interferon regulatory factor 7 (human) that has been cysteinylated on the residue at the position equivalent to Cys-191 of the amino acid sequence represented by UniProtKB:Q92985-1. Example: UniProtKB:Q92985-1, Cys-191, MOD:00765." [IEDB_epitope:1336456, PRO:DNx]


organism-modification



PR:000078397

interferon regulatory factor 7 methylated 1 (human)

hIRF7/Me:1


"An interferon regulatory factor 7 (human) that has been methylated on the residue at the position equivalent to Cys-97 of the amino acid sequence represented by UniProtKB:Q92985-1. Example: UniProtKB:Q92985-1, Cys-97, MOD:00660." [IEDB_epitope:1027266, PRO:DNx]


organism-modification



PR:000080104

interferon regulatory factor 7 cysteinylated 2 (human)

hIRF7/Cyst:2


"An interferon regulatory factor 7 (human) that has been cysteinylated on the residue at the position equivalent to Cys-39 of the amino acid sequence represented by UniProtKB:Q92985-1. Example: UniProtKB:Q92985-1, Cys-39, MOD:00765." [IEDB_epitope:1593091, PRO:DNx]


organism-modification



PR:000080211

interferon regulatory factor 7 methylated 2 (human)

hIRF7/Me:2


"An interferon regulatory factor 7 (human) that has been methylated on the residue at the position equivalent to Cys-191 of the amino acid sequence represented by UniProtKB:Q92985-1. Example: UniProtKB:Q92985-1, Cys-191, MOD:00660." [IEDB_epitope:1039161, PRO:DNx]


sequence



PR:000003261

interferon regulatory factor 7 isoform 1

IRF7/iso:1


"An interferon regulatory factor 7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92985-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:Q92985-1

interferon regulatory factor 7 isoform A (human)

hIRF7/iso:A


"An interferon regulatory factor 7 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000027082

interferon regulatory factor 7 isoform 1 phosphorylated 1 (human)

hIRF7/iso:1/Phos:1


"An interferon regulatory factor 7 isoform 1 phosphorylated 1 in human. UniProtKB:Q92985-1, Ser-477/Ser-479, MOD:00046." [PMID:10893229, PMID:14517278, TLR:AMM]


Yes
organism-modification



PR:000037791

interferon regulatory factor 7 isoform 1 unphosphorylated 1 (human)

hIRF7/iso:1/UnPhos:1


"An interferon regulatory factor 7 isoform 1 unphosphorylated 1 in human. UniProtKB:Q92985-1, Ser-477/Ser-479, PR:000026291." [PMID:10893229, PMID:14517278, PRO:CNA]

Yes

modification



PR:000003280

interferon regulatory factor 7 isoform 1 phosphorylated form

IRF7/iso:1/PhosRes+


"An interferon regulatory factor 7 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000003281

interferon regulatory factor 7 isoform 1 phosphorylated 1

IRF7/iso:1/Phos:1


"An interferon regulatory factor 7 isoform 1 phosphorylated form that has been activated by phosphorylation on the Ser residues located in the C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit. Example: UniProtKB:Q92985-1, Ser-477/Ser-479, MOD:00046." [PMID:10893229, PMID:14517278, PMID:20043992, TLR:AMM]


organism-modification



PR:000027082

interferon regulatory factor 7 isoform 1 phosphorylated 1 (human)

hIRF7/iso:1/Phos:1


"An interferon regulatory factor 7 isoform 1 phosphorylated 1 in human. UniProtKB:Q92985-1, Ser-477/Ser-479, MOD:00046." [PMID:10893229, PMID:14517278, TLR:AMM]


Yes
modification



PR:000037790

interferon regulatory factor 7 isoform 1 unphosphorylated 1

IRF7/iso:1/UnPhos:1


"An interferon regulatory factor 7 isoform 1 that lacks phosphorylation on the Ser residues located in the C-terminal region that actives dimerization. Example: UniProtKB:Q92985-1, Ser-477/Ser-479, PR:000026291." [PMID:10893229, PMID:14517278, PMID:20043992, PRO:CNA]


organism-modification



PR:000037791

interferon regulatory factor 7 isoform 1 unphosphorylated 1 (human)

hIRF7/iso:1/UnPhos:1


"An interferon regulatory factor 7 isoform 1 unphosphorylated 1 in human. UniProtKB:Q92985-1, Ser-477/Ser-479, PR:000026291." [PMID:10893229, PMID:14517278, PRO:CNA]

Yes

modification



PR:000028703

interferon regulatory factor 7 unmodified form

IRF7/UnMod


"An interferon regulatory factor 7 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]


organism-modification



PR:000028704

interferon regulatory factor 7 unmodified form (human)

hIRF7/UnMod


"An interferon regulatory factor 7 unmodified form in human." [PRO:CNA]


Yes
gene



PR:000002050

interferon regulatory factor 8

IRF8


"An interferon regulatory factor 3-9 that is a translation product of the human IRF8 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:P23611

interferon regulatory factor 8 (mouse)

mIRF8


"An interferon regulatory factor 8 that is encoded in the genome of mouse." [OMA:P23611, PRO:DNx]


organism-sequence



PR:P23611-1

interferon regulatory factor 8 isoform 1 (mouse)

mIRF8/iso:1


"An interferon regulatory factor 8 isoform 1 that is encoded in the genome of mouse." [PMID:2111015, PRO:HJD]


organism-modification



PR:000035707

interferon regulatory factor 8 isoform 1 sumoylated 1 (mouse)

mIRF8/iso:1/Sumo:1


"An interferon regulatory factor 8 isoform 1 sumoylated 1 in mouse. UniProtKB:P23611-1, Lys-310, MOD:01149." [PMID:22942423, PRO:HJD]

Yes

organism-modification



PR:000035709

interferon regulatory factor 8 isoform 1 unsumoylated form (mouse)

mIRF8/iso:1/SumoRes-


"An interferon regulatory factor 8 isoform 1 unsumoylated form in mouse." [PMID:22942423, PRO:HJD]

Yes

organism-gene



PR:Q02556

interferon regulatory factor 8 (human)

hIRF8


"An interferon regulatory factor 8 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q02556]


organism-modification



PR:000067923

interferon regulatory factor 8 methylated 1 (human)

hIRF8/Me:1


"An interferon regulatory factor 8 (human) that has been methylated on the residue at the position equivalent to Cys-410 of the amino acid sequence represented by UniProtKB:Q02556. UniProtKB:Q02556, Cys-410, MOD:00660." [IEDB_epitope:1033280, PRO:DNx]


organism-gene



PR:Q90871

interferon regulatory factor 8 (chicken)

chick-IRF8


"An interferon regulatory factor 8 that is encoded in the genome of chicken." [OMA:Q90871, PRO:DNx]


sequence



PR:000035704

interferon regulatory factor 8 isoform 1

IRF8/iso:1


"An interferon regulatory factor 8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23611-1 or a 1:1 ortholog thereof." [PMID:22942423, PRO:HJD]


organism-sequence



PR:P23611-1

interferon regulatory factor 8 isoform 1 (mouse)

mIRF8/iso:1


"An interferon regulatory factor 8 isoform 1 that is encoded in the genome of mouse." [PMID:2111015, PRO:HJD]


organism-modification



PR:000035707

interferon regulatory factor 8 isoform 1 sumoylated 1 (mouse)

mIRF8/iso:1/Sumo:1


"An interferon regulatory factor 8 isoform 1 sumoylated 1 in mouse. UniProtKB:P23611-1, Lys-310, MOD:01149." [PMID:22942423, PRO:HJD]

Yes

organism-modification



PR:000035709

interferon regulatory factor 8 isoform 1 unsumoylated form (mouse)

mIRF8/iso:1/SumoRes-


"An interferon regulatory factor 8 isoform 1 unsumoylated form in mouse." [PMID:22942423, PRO:HJD]

Yes

modification



PR:000035706

interferon regulatory factor 8 isoform 1 sumoylated 1

IRF8/iso:1/Sumo:1


"An interferon regulatory factor 8 isoform 1 that has been post-translationally modified to have a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) with SUMO3. Example: UniProtKB:P23611-1, Lys-310, MOD:01149." [PMID:22942423, PRO:HJD]


organism-modification



PR:000035707

interferon regulatory factor 8 isoform 1 sumoylated 1 (mouse)

mIRF8/iso:1/Sumo:1


"An interferon regulatory factor 8 isoform 1 sumoylated 1 in mouse. UniProtKB:P23611-1, Lys-310, MOD:01149." [PMID:22942423, PRO:HJD]

Yes

modification



PR:000035708

interferon regulatory factor 8 isoform 1 unsumoylated form

IRF8/iso:1/SumoRes-


"An interferon regulatory factor 8 isoform 1 that lacks sumoylated residues." [PMID:22942423, PRO:HJD]


organism-modification



PR:000035709

interferon regulatory factor 8 isoform 1 unsumoylated form (mouse)

mIRF8/iso:1/SumoRes-


"An interferon regulatory factor 8 isoform 1 unsumoylated form in mouse." [PMID:22942423, PRO:HJD]

Yes

gene



PR:000002051

interferon regulatory factor 9

IRF9


"An interferon regulatory factor 3-9 that is a translation product of the human IRF9 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:Q00978

interferon regulatory factor 9 (human)

hIRF9


"An interferon regulatory factor 9 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q00978]


organism-sequence



PR:Q00978-1

interferon regulatory factor 9 isoform 1 (human)

hIRF9/iso:1


"An interferon regulatory factor 9 isoform 1 that is encoded in the genome of human." [PRO:PD]


organism-modification



PR:000028650

interferon regulatory factor 9 isoform 1 acetylated 1 (human)

hIRF9/iso:1/Ac:1


"An interferon regulatory factor 9 isoform 1 acetylated 1 in human. UniProtKB:Q00978-1, Lys-81, MOD:00064." [PMID:17923090, PRO:PD]


organism-modification



PR:000070535

interferon regulatory factor 9 methylated 1 (human)

hIRF9/Me:1


"An interferon regulatory factor 9 (human) that has been methylated on the residue at the position equivalent to Cys-294 of the amino acid sequence represented by UniProtKB:Q00978. UniProtKB:Q00978, Cys-294, MOD:00660." [IEDB_epitope:1042554, PRO:DNx]


organism-modification



PR:000080766

interferon regulatory factor 9 phosphorylated 1 (human)

hIRF9/Phos:1


"An interferon regulatory factor 9 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-109 of the amino acid sequence represented by UniProtKB:Q00978. UniProtKB:Q00978, Tyr-109, MOD:00048." [IEDB_epitope:2148299, PRO:DNx]


organism-gene



PR:Q61179

interferon regulatory factor 9 (mouse)

mIRF9


"An interferon regulatory factor 9 that is encoded in the genome of mouse." [OMA:Q61179, PRO:DNx]


sequence



PR:000028647

interferon regulatory factor 9 isoform 1

IRF9/iso:1


"An interferon regulatory factor 9 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q00978-1 or a 1:1 ortholog thereof." [PMID:17923090, PRO:PD]


organism-sequence



PR:Q00978-1

interferon regulatory factor 9 isoform 1 (human)

hIRF9/iso:1


"An interferon regulatory factor 9 isoform 1 that is encoded in the genome of human." [PRO:PD]


organism-modification



PR:000028650

interferon regulatory factor 9 isoform 1 acetylated 1 (human)

hIRF9/iso:1/Ac:1


"An interferon regulatory factor 9 isoform 1 acetylated 1 in human. UniProtKB:Q00978-1, Lys-81, MOD:00064." [PMID:17923090, PRO:PD]


modification



PR:000028649

interferon regulatory factor 9 isoform 1 acetylated 1

IRF9/iso:1/Ac:1


"An interferon regulatory factor 9 isoform 1 that has been acetylated on the Lys residue located within the conserved sequence WKTRLRC within DNA binding domain. Example: UniProtKB:Q00978-1, Lys-81, MOD:00064." [PMID:17923090, PRO:PD]


organism-modification



PR:000028650

interferon regulatory factor 9 isoform 1 acetylated 1 (human)

hIRF9/iso:1/Ac:1


"An interferon regulatory factor 9 isoform 1 acetylated 1 in human. UniProtKB:Q00978-1, Lys-81, MOD:00064." [PMID:17923090, PRO:PD]


Back to top
cheY/iso:1/InitMet- forms found in complexes   

cheY/iso:1/InitMet- Component
Complexes
PR:000025763 hIRF3/iso:1/Phos:1 PR:000036002 IRF3-P:IRF3-P:KPNA4 complex (human)
PR:000027082 hIRF7/iso:1/Phos:1 PR:000027084 IRF3-P:IRF7-P complex (human)
PR:000027086 IRF7-P:IRF7-P complex (human)
PR:000027094 mIRF5/iso:1/Phos:1 PR:000027536 IRF5-P:IRF5-P (mouse)
PR:000027096 mIRF5/iso:2/Phos:1 PR:000027537 IRF5BMv-P:IRF5BMv-P (mouse)
PR:000027097 mIRF3/iso:1/Phos:1 PR:000027098 IRF3-P:IRF3-P complex (mouse)
PR:000036043 IRF3-P:p65 complex (mouse)
PR:000036047 IRF3-P:p65:ISRE complex (mouse)
PR:000028702 hIRF3/UnMod PR:000036030 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036036 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000037354 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037358 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000028704 hIRF7/UnMod PR:000036034 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036038 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000037356 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000037360 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)
PR:000045488 hIRF3/Phos:1 PR:000025765 IRF3-P:IRF3-P complex (human)
PR:000045489 hIRF3/iso:1/Phos:2 PR:000027084 IRF3-P:IRF7-P complex (human)
PR:Q14653 hIRF3 PR:000036045 IRF3:XPO1 complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000025763 hIRF3/iso:1/Phos:1
UniProtKB:Q14653-1, Ser-385/Ser-386, MOD:00046
enablesGO:0005515 protein binding with PR:O14980 chromosome region maintenance 1 protein homolog (human) PMID:10805757
located_inGO:0005829 cytosol Reactome:REACT_7149
PR:000035707 mIRF8/iso:1/Sumo:1
UniProtKB:P23611-1, Lys-310, MOD:01149
acts_upstream_of_or_withinNOT GO:0060261 positive regulation of transcription initiation by RNA polymerase II MGI_ref:5448615; PMID:22942423
located_inGO:0005634 nucleus MGI_ref:5448615; PMID:22942423
PR:000035709 mIRF8/iso:1/SumoRes- acts_upstream_of_or_withinGO:0060261 positive regulation of transcription initiation by RNA polymerase II MGI_ref:5448615; PMID:22942423
located_inGO:0005634 nucleus MGI_ref:5448615; PMID:22942423
PR:000037791 hIRF7/iso:1/UnPhos:1
UniProtKB:Q92985-1, Ser-477/Ser-479, PR:000026291
located_inGO:0005737 cytoplasm Reactome:REACT_21735
PR:P70671-1 mIRF3/iso:1 located_inGO:0005737 cytoplasm MGI_ref:3828224; PMID:18851954