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family
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 PR:000022007 |
   vertebrate-like neuraminidase
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   PRG2/iso:1/EMBP
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  "A protein that is a glycohydrolytic enzyme, which removes sialic acid residues from a variety of sialoglycoconjugates. Sialidases have highly conserved active site residues, the F/YRIV/P motif in the N-terminal part and the Asp boxes (consensus S/TXD(x)GxTW/F present as three to five repeat in the protein) similar to their viral and bacterial counter parts." [PMID:12374200]
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gene
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 PR:000011145 |
   sialidase-1
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   NEU1
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  "A vertebrate-like neuraminidase that is a translation product of the human NEU1 gene or a 1:1 ortholog thereof." [PRO:DNx]
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organism-gene
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 PR:O35657 |
   sialidase-1 (mouse)
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   mNEU1
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  "A sialidase-1 that is encoded in the genome of mouse." [OMA:O35657, PRO:DNx]
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organism-gene
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 PR:Q99519 |
   sialidase-1 (human)
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   hNEU1
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  "A sialidase-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99519]
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organism-modification
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 PR:000048582 |
   sialidase-1, signal peptide removed form (human)
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   hNEU1/SigPep-
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  "A sialidase-1 (human) that has had the signal peptide removed. UniProtKB:Q99519, 48-415." [PRO:DNx, Reactome:R-HSA-1605788]
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organism-modification
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 PR:000064272 |
   sialidase-1 sequence variant R303P, signal peptide removed form (human)
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   hNEU1/var:R303P/SigPep-
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  "A sialidase-1 (human) that has a Pro residue at the position equivalent to Arg-303 of the amino acid sequence represented by UniProtKB:Q99519 and that has had the signal peptide removed. UniProtKB:Q99519, 48-415, Arg-303, CHEBI:50342." [PRO:DNx, Reactome:R-HSA-5674182]
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organism-modification
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 PR:000064587 |
   sialidase-1 sequence variant R225P, signal peptide removed form (human)
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   hNEU1/var:R225P/SigPep-
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  "A sialidase-1 (human) that has a Pro residue at the position equivalent to Arg-225 of the amino acid sequence represented by UniProtKB:Q99519 and that has had the signal peptide removed. UniProtKB:Q99519, 48-415, Arg-225, CHEBI:50342." [PRO:DNx, Reactome:R-HSA-5674167]
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organism-modification
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 PR:000072682 |
   sialidase-1 hydroxylated 1 (human)
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   hNEU1/Hy:1
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  "A sialidase-1 (human) that has been hydroxylated on the residue at the position equivalent to Trp-240 of the amino acid sequence represented by UniProtKB:Q99519. UniProtKB:Q99519, Trp-240, MOD:01622." [IEDB_epitope:1321159, PRO:DNx]
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organism-gene
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 PR:Q99PW3 |
   sialidase-1 (rat)
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   rNEU1
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  "A sialidase-1 that is encoded in the genome of rat." [OMA:Q99PW3, PRO:DNx]
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modification
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 PR:000020732 |
   sialidase-1, signal peptide removed form
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   NEU1/SigPep-
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  "A sialidase-1 that has had the signal peptide removed." [PRO:DNx]
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organism-modification
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 PR:000048582 |
   sialidase-1, signal peptide removed form (human)
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   hNEU1/SigPep-
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  "A sialidase-1 (human) that has had the signal peptide removed. UniProtKB:Q99519, 48-415." [PRO:DNx, Reactome:R-HSA-1605788]
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organism-modification
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 PR:000064272 |
   sialidase-1 sequence variant R303P, signal peptide removed form (human)
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   hNEU1/var:R303P/SigPep-
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  "A sialidase-1 (human) that has a Pro residue at the position equivalent to Arg-303 of the amino acid sequence represented by UniProtKB:Q99519 and that has had the signal peptide removed. UniProtKB:Q99519, 48-415, Arg-303, CHEBI:50342." [PRO:DNx, Reactome:R-HSA-5674182]
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organism-modification
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|
 PR:000064587 |
   sialidase-1 sequence variant R225P, signal peptide removed form (human)
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   hNEU1/var:R225P/SigPep-
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  "A sialidase-1 (human) that has a Pro residue at the position equivalent to Arg-225 of the amino acid sequence represented by UniProtKB:Q99519 and that has had the signal peptide removed. UniProtKB:Q99519, 48-415, Arg-225, CHEBI:50342." [PRO:DNx, Reactome:R-HSA-5674167]
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gene
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 PR:000011146 |
   sialidase-2
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   NEU2
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  "A vertebrate-like neuraminidase that is a translation product of the human NEU2 gene or a 1:1 ortholog thereof." [PRO:DNx]
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organism-gene
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 PR:Q64627 |
   sialidase-2 (rat)
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   rNEU2
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  "A sialidase-2 that is encoded in the genome of rat." [OMA:Q64627, PRO:DNx]
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organism-gene
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 PR:Q9JMH3 |
   sialidase-2 (mouse)
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   mNEU2
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  "A sialidase-2 that is encoded in the genome of mouse." [OMA:Q9JMH3, PRO:DNx]
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organism-gene
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 PR:Q9Y3R4 |
   sialidase-2 (human)
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   hNEU2
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  "A sialidase-2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9Y3R4]
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gene
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 PR:000011147 |
   sialidase-3
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   NEU3
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  "A vertebrate-like neuraminidase that is a translation product of the human NEU3 gene or a 1:1 ortholog thereof." [PRO:DNx]
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organism-gene
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 PR:Q99PW5 |
   sialidase-3 (rat)
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   rNEU3
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  "A sialidase-3 that is encoded in the genome of rat." [OMA:Q99PW5, PRO:DNx]
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organism-sequence
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 PR:Q99PW5-1 |
   sialidase-3 isoform 1 (rat)
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   rNEU3/iso:1
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  "A sialidase-3 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
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organism-gene
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 PR:Q9JMH7 |
   sialidase-3 (mouse)
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   mNEU3
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  "A sialidase-3 that is encoded in the genome of mouse." [OMA:Q9JMH7, PRO:DNx]
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organism-sequence
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 PR:Q9JMH7-1 |
   sialidase-3 isoform 1 (mouse)
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   mNEU3/iso:1
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  "A sialidase-3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
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organism-gene
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 PR:Q9UQ49 |
   sialidase-3 (human)
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   hNEU3
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  "A sialidase-3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UQ49]
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organism-sequence
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 PR:Q9UQ49-1 |
   sialidase-3 isoform h1 (human)
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   hNEU3/iso:h1
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  "A sialidase-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UQ49-1." [PRO:DNx, UniProtKB:Q9UQ49]
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organism-sequence
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 PR:Q9UQ49-2 |
   sialidase-3 isoform h2 (human)
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   hNEU3/iso:h2
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  "A sialidase-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UQ49-2." [PRO:DNx, UniProtKB:Q9UQ49]
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organism-modification
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 PR:000071989 |
   sialidase-3 phosphorylated 1 (human)
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   hNEU3/Phos:1
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  "A sialidase-3 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-346 of the amino acid sequence represented by UniProtKB:Q9UQ49-1. Example: UniProtKB:Q9UQ49-1, Tyr-346, MOD:00048." [IEDB_epitope:2149157, PRO:DNx]
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organism-modification
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 PR:000078640 |
   sialidase-3 cysteinylated 1 (human)
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   hNEU3/Cyst:1
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  "A sialidase-3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-356 of the amino acid sequence represented by UniProtKB:Q9UQ49-1. Example: UniProtKB:Q9UQ49-1, Cys-356, MOD:00765." [IEDB_epitope:1055023, PRO:DNx]
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organism-modification
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 PR:000083851 |
   sialidase-3 cysteinylated 2 (human)
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   hNEU3/Cyst:2
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  "A sialidase-3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-250 of the amino acid sequence represented by UniProtKB:Q9UQ49-1. Example: UniProtKB:Q9UQ49-1, Cys-250, MOD:00765." [IEDB_epitope:1337994, PRO:DNx]
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sequence
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 PR:000043450 |
   sialidase-3 isoform 1
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   NEU3/iso:1
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  "A sialidase-3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JMH7-1 or a 1:1 ortholog thereof." [PRO:DNx]
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organism-sequence
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 PR:Q99PW5-1 |
   sialidase-3 isoform 1 (rat)
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   rNEU3/iso:1
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  "A sialidase-3 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
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organism-sequence
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 PR:Q9JMH7-1 |
   sialidase-3 isoform 1 (mouse)
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   mNEU3/iso:1
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  "A sialidase-3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
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gene
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|
 PR:000011148 |
   sialidase-4
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   NEU4
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  "A vertebrate-like neuraminidase that is a translation product of the human NEU4 gene or a 1:1 ortholog thereof." [PRO:DNx]
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organism-gene
 |


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 PR:Q8BZL1 |
   sialidase-4 (mouse)
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   mNEU4
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  "A sialidase-4 that is encoded in the genome of mouse." [OMA:Q8BZL1, PRO:DNx]
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organism-sequence
 |


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 PR:Q8BZL1-1 |
   sialidase-4 isoform m2 (mouse)
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   mNEU4/iso:m2
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  "A sialidase-4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BZL1-1." [PRO:DNx, UniProtKB:Q8BZL1]
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organism-sequence
 |


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 PR:Q8BZL1-2 |
   sialidase-4 isoform m1 (mouse)
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   mNEU4/iso:m1
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  "A sialidase-4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BZL1-2." [PRO:DNx, UniProtKB:Q8BZL1]
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organism-gene
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 PR:Q8WWR8 |
   sialidase-4 (human)
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   hNEU4
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  "A sialidase-4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8WWR8]
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organism-sequence
 |


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 PR:Q8WWR8-1 |
   sialidase-4 isoform h1 (human)
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   hNEU4/iso:h1
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  "A sialidase-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WWR8-1." [PRO:DNx, UniProtKB:Q8WWR8]
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organism-sequence
 |


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 PR:Q8WWR8-2 |
   sialidase-4 isoform h2 (human)
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   hNEU4/iso:h2
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  "A sialidase-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WWR8-2." [PRO:DNx, UniProtKB:Q8WWR8]
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organism-sequence
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 PR:Q8WWR8-3 |
   sialidase-4 isoform h3 (human)
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   hNEU4/iso:h3
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  "A sialidase-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WWR8-3." [PRO:DNx, UniProtKB:Q8WWR8]
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