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PRO ID
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| PRO name | interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 |
| Synonyms | | PRO-Short-label: | EXACT: | IRAK1/iso:1/Phos:3 | | Other: | EXACT: | interleukin-1 receptor-associated kinase 1 active | pp-IRAK1 |
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| Definition | "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated form in which the phosphorylation by interleukin-1 receptor-associated kinase 4 (IRAK-4) occurs on the conserved Thr residue (Thr-209 in human) located near the N terminus of the kinase domain, and on a Thr residue located in the activation loop (Thr-387 in human). The latter phosphorylation is the second step following the activation of the TLR/IL-1 receptor complex. Example: UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047." [PMID:14625308, PRO:CNA, PRO:DAN] |
| PRO Category | modification |
| Parent | PR:000021971 interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated form
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| Terms by PRO Category |
| Organism-Independent |
Organism-Specific |
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Number of Terms | | Modification | 1 |
Organism-Modification |
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