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Protein Ontology report - amyloid-beta precursor protein, signal peptide removed form
PR:000019035 - http://purl.obolibrary.org/obo/PR_000019035
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000019035   
  PRO nameamyloid-beta precursor protein, signal peptide removed form 
  Synonyms
PRO-Short-label: EXACT:APP/SigPep-
  Definition"An amyloid-beta precursor protein that has had the signal peptide removed." [PRO:DNx] 
  CommentRequested by=Alzforum. 
  PRO Categorymodification 
  ParentPR:000004168 amyloid-beta precursor protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification22                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
modification



PR:000019035

amyloid-beta precursor protein, signal peptide removed form

APP/SigPep-


"An amyloid-beta precursor protein that has had the signal peptide removed." [PRO:DNx]


modification



PR:000025548

amyloid-beta precursor protein isoform APP770, signal peptide removed form

APP/iso:APP770/SigPep-


"An amyloid-beta precursor protein isoform APP770 that has had the signal peptide removed." [PRO:DAN]


modification



PR:000025549

amyloid-beta precursor protein isoform APP305, signal peptide removed form

APP/iso:APP305/SigPep-


"An amyloid-beta precursor protein isoform APP305 that has had the signal peptide removed." [PRO:DAN]


modification



PR:000025550

amyloid-beta precursor protein isoform L-APP677, signal peptide removed form

APP/iso:L-APP677/SigPep-


"An amyloid-beta precursor protein isoform L-APP677 that has had the signal peptide removed." [PRO:DAN]


modification



PR:000025551

amyloid-beta precursor protein isoform APP695, signal peptide removed form

APP/iso:APP695/SigPep-


"An amyloid-beta precursor protein isoform APP695 that has had the signal peptide removed." [PRO:DAN]


organism-modification



PR:000085805

amyloid-beta precursor protein isoform APP695, signal peptide removed form (human)

hAPP/iso:APP695/SigPep-


"An amyloid-beta precursor protein isoform APP695 (human) that has had the signal peptide removed. UniProtKB:P05067-4, 18-695." [PRO:DNx, Reactome:R-HSA-9839060]


modification



PR:000025552

amyloid-beta precursor protein isoform L-APP696, signal peptide removed form

APP/iso:L-APP696/SigPep-


"An amyloid-beta precursor protein isoform L-APP696 that has had the signal peptide removed." [PRO:DAN]


modification



PR:000025553

amyloid-beta precursor protein isoform APP714, signal peptide removed form

APP/iso:APP714/SigPep-


"An amyloid-beta precursor protein isoform APP714 that has had the signal peptide removed." [PRO:DAN]


modification



PR:000025554

amyloid-beta precursor protein isoform L-APP733, signal peptide removed form

APP/iso:L-APP733/SigPep-


"An amyloid-beta precursor protein isoform L-APP733 that has had the signal peptide removed." [PRO:DAN]


modification



PR:000025555

amyloid-beta precursor protein isoform APP751, signal peptide removed form

APP/iso:APP751/SigPep-


"An amyloid-beta precursor protein isoform APP751 that has had the signal peptide removed." [PRO:DAN]


modification



PR:000025556

amyloid-beta precursor protein isoform L-APP752, signal peptide removed form

APP/iso:L-APP752/SigPep-


"An amyloid-beta precursor protein isoform L-APP752 that has had the signal peptide removed." [PRO:DAN]


modification



PR:000025557

amyloid-beta precursor protein isoform APP639, signal peptide removed form

APP/iso:APP639/SigPep-


"An amyloid-beta precursor protein isoform APP639 that has had the signal peptide removed." [PRO:DAN]


modification



PR:000025577

soluble APP-alpha

S-APP-alpha


"An amyloid-beta precursor protein proteolytic cleavage product that is the N-terminal product of cleavage by alpha-secretase of amyloid-beta precursor protein, signal peptide removed form. Example: UniProtKB:P05067-1, 18-687." [PRO:DAN]


modification



PR:000025578

soluble APP-beta

S-APP-beta


"An amyloid-beta precursor protein proteolytic cleavage product that is the N-terminal product of cleavage by beta-secretase of amyloid-beta precursor protein, signal peptide removed form. Example: UniProtKB:P05067-1, 18-671." [PRO:DAN]


modification



PR:000025579

soluble APP-theta

S-APP-theta


"An amyloid-beta precursor protein proteolytic cleavage product that is the N-terminal product of cleavage by theta-secretase of amyloid-beta precursor protein, signal peptide removed form." [PRO:DAN]


modification



PR:000025580

C99

APP-C99


"An amyloid-beta precursor protein proteolytic cleavage product that is the C-terminal product of cleavage by beta-secretase of certain amyloid-beta precursor protein isoforms, signal peptide removed form. Example: UniProtKB:P05067-1, 672-770." [PRO:DAN]


modification



PR:000036193

amyloid beta peptide

Abeta


"An amyloid-beta precursor protein proteolytic cleavage product that is the N-terminal chain produced by gamma-secretase cleavage of C99." [PMID:19828817, PRO:DAN]


modification



PR:000025583

beta-amyloid protein 42

Abeta(1-42)


"An amyloid beta peptide that corresponds residues 1-42 of C99. Example: UniProtKB:P05067-1, 672-713." [PRO:DAN]


organism-modification



PR:000050063

beta-amyloid protein 42 (human)

hAbeta(1-42)


"A beta-amyloid protein 42 in human. Example: UniProtKB:P05067-1, 672-713." [PRO:DAN]


modification



PR:000025584

beta-amyloid protein 40

Abeta(1-40)


"An amyloid beta peptide that corresponds to residues 1-40 of C99. Example: UniProtKB:P05067-1, 672-711." [PRO:DAN]


organism-modification



PR:000050064

beta-amyloid protein 40 (human)

hAbeta(1-40)


"A beta-amyloid protein 40 in human. Example: UniProtKB:P05067-1, 672-711." [PRO:DAN]


organism-modification



PR:000085741

beta-amyloid protein 40 (mouse)

mAbeta(1-40)


"A beta-amyloid protein 40 in mouse. Example: UniProtKB:P12023-1, 672-711." [PRO:DAN]


modification



PR:000025581

C83

APP-C83


"An amyloid-beta precursor protein proteolytic cleavage product that is the C-terminal product of cleavage by alpha-secretase of certain amyloid-beta precursor protein isoforms, signal peptide removed form. Example: UniProtKB:P05067-1, 688-770." [PRO:DAN]


modification



PR:000025587

P3(42)

APP-P3(42)


"An amyloid-beta precursor protein proteolytic cleavage product that is the N-terminal chain of 26 amino acid residues produced by gamma-secretase cleavage of C83." [PRO:DAN]


modification



PR:000025588

P3(40)

APP-P3(40)


"An amyloid-beta precursor protein proteolytic cleavage product that is the N-terminal chain of 24 amino acid residues produced by gamma-secretase cleavage of C83." [PRO:DAN]


modification



PR:000025582

C80

APP-C80


"An amyloid-beta precursor protein proteolytic cleavage product that is the C-terminal product of cleavage by theta-secretase of certain amyloid-beta precursor protein isoforms, signal peptide removed form. Example: UniProtKB:P05067-1, 691-770." [PRO:DAN]


organism-modification



PR:000046368

amyloid-beta precursor protein, signal peptide removed form (human)

hAPP/SigPep-


"An amyloid-beta precursor protein (human) that has had the signal peptide removed. UniProtKB:P05067, 18-770." [PRO:DNx, Reactome:R-HSA-139835, Reactome:R-HSA-49335, Reactome:R-HSA-5229077, Reactome:R-HSA-5229136]


organism-modification



PR:000062305

amyloid-beta precursor protein, signal peptide removed phosphorylated form (human)

hAPP/SigPep-/PhosRes+


"An amyloid-beta precursor protein (human) that has had the signal peptide removed and that includes at least one phosphorylated residue. Example: UniProtKB:P05067-1, 18-770, MOD:00696." [PRO:DNx, Reactome:R-HSA-8957012]


organism-modification



PR:000085805

amyloid-beta precursor protein isoform APP695, signal peptide removed form (human)

hAPP/iso:APP695/SigPep-


"An amyloid-beta precursor protein isoform APP695 (human) that has had the signal peptide removed. UniProtKB:P05067-4, 18-695." [PRO:DNx, Reactome:R-HSA-9839060]