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Protein Ontology report - thrombospondin-1, signal peptide removed form
PR:000018282 - http://purl.obolibrary.org/obo/PR_000018282
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000018282   
  PRO namethrombospondin-1, signal peptide removed form 
  Synonyms
PRO-Short-label: EXACT:THBS1/SigPep-
  Definition"A thrombospondin-1 that has had the signal peptide removed." [PRO:DNx] 
  PRO Categorymodification 
  ParentPR:000000129 thrombospondin-1
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification5                                                  Organism-Modification 10                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000018282 thrombospondin-1, signal peptide removed form
THBS1/SigPep-

modification


PR:000000587 thrombospondin-1 isoform 1, signal peptide removed form
THBS1/iso:1/SigPep-

modification


PR:000000485 thrombospondin-1 isoform 1 cleaved and glycosylated form
THBS1/iso:1/ClvGlyco+

modification


PR:000000590 thrombospondin-1 isoform 1 cleaved 2 glycosylated form
THBS1/iso:1/Clv:2/GlycoRes+

organism-modification


PR:000036489 thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human)
hTHBS1/iso:1/Clv:2/Glyco:1

organism-modification


PR:000036490 thrombospondin-1 isoform 1 cleaved 2 glycosylated form (mouse)
mTHBS1/iso:1/Clv:2/GlycoRes+
Yes
modification


PR:000000589 thrombospondin-1 isoform 1, signal peptide removed glycosylated form
THBS1/iso:1/SigPep-/GlycoRes+

organism-modification


PR:000036487 thrombospondin-1 isoform 1, signal peptide removed glycosylated form (mouse)
mTHBS1/iso:1/SigPep-/GlycoRes+
Yes
organism-modification


PR:000036488 thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human)
hTHBS1/iso:1/SigPep-/Glyco:1
Yes
organism-modification


PR:000026338 thrombospondin-1 isoform 1, signal peptide removed form (human)
hTHBS1/iso:1/SigPep-
Yes
organism-modification


PR:000036488 thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human)
hTHBS1/iso:1/SigPep-/Glyco:1
Yes
organism-modification


PR:000036489 thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human)
hTHBS1/iso:1/Clv:2/Glyco:1

organism-modification


PR:000036485 thrombospondin-1 isoform 1, signal peptide removed form (mouse)
mTHBS1/iso:1/SigPep-
Yes
organism-modification


PR:000036487 thrombospondin-1 isoform 1, signal peptide removed glycosylated form (mouse)
mTHBS1/iso:1/SigPep-/GlycoRes+
Yes
organism-modification


PR:000036490 thrombospondin-1 isoform 1 cleaved 2 glycosylated form (mouse)
mTHBS1/iso:1/Clv:2/GlycoRes+
Yes
organism-modification


PR:000028410 thrombospondin-1, signal peptide removed form (human)
hTHBS1/SigPep-
Yes
Yes
organism-modification


PR:000026338 thrombospondin-1 isoform 1, signal peptide removed form (human)
hTHBS1/iso:1/SigPep-
Yes
organism-modification


PR:000036488 thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human)
hTHBS1/iso:1/SigPep-/Glyco:1
Yes
organism-modification


PR:000036489 thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human)
hTHBS1/iso:1/Clv:2/Glyco:1

organism-modification


PR:000064777 thrombospondin-1, signal peptide removed O-glycosylserine form (human)
hTHBS1/SigPep-/OGlycoSer+

organism-modification


PR:000060409 thrombospondin-1, signal peptide removed fucosylserine form (human)
hTHBS1/SigPep-/FucSer+

organism-modification


PR:000036488 thrombospondin-1 isoform 1, signal peptide removed glycosylated 1 (human)
hTHBS1/iso:1/SigPep-/Glyco:1
Yes
organism-modification


PR:000036489 thrombospondin-1 isoform 1 cleaved 2 glycosylated 1 (human)
hTHBS1/iso:1/Clv:2/Glyco:1

organism-modification


PR:000044495 thrombospondin-1, signal peptide removed form (mouse)
mTHBS1/SigPep-
Yes
organism-modification


PR:000036485 thrombospondin-1 isoform 1, signal peptide removed form (mouse)
mTHBS1/iso:1/SigPep-
Yes
organism-modification


PR:000036487 thrombospondin-1 isoform 1, signal peptide removed glycosylated form (mouse)
mTHBS1/iso:1/SigPep-/GlycoRes+
Yes
organism-modification


PR:000036490 thrombospondin-1 isoform 1 cleaved 2 glycosylated form (mouse)
mTHBS1/iso:1/Clv:2/GlycoRes+
Yes
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THBS1/SigPep- forms found in complexes   

THBS1/SigPep- Component
 Complexes
PR:000028410 hTHBS1/SigPep- PR:000028445 integrin alphaIIbbeta3:thrombospondin 1 (human)
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0016525 negative regulation of angiogenesisPR:000036490 mTHBS1/iso:1/Clv:2/GlycoRes+ PMID:17082774
GO:0060055 angiogenesis involved in wound healingPR:000036490 mTHBS1/iso:1/Clv:2/GlycoRes+ PMID:17082774

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0004866 endopeptidase inhibitor activityPR:000026338 hTHBS1/iso:1/SigPep- PMID:8751720
GO:0005515 protein bindingPR:000036487 mTHBS1/iso:1/SigPep-/GlycoRes+ PMID:1459996
PR:000036488 hTHBS1/iso:1/SigPep-/Glyco:1 PMID:3305519
GO:0050431 transforming growth factor beta bindingPR:000036487 mTHBS1/iso:1/SigPep-/GlycoRes+ PMID:9657149
PR:000036488 hTHBS1/iso:1/SigPep-/Glyco:1 PMID:15342643

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005615 extracellular spacePR:000026338 hTHBS1/iso:1/SigPep- PMID:15662972
PR:000028410 hTHBS1/SigPep- PMID:15662972
PR:000036485 mTHBS1/iso:1/SigPep- PMID:12498716
PR:000036487 mTHBS1/iso:1/SigPep-/GlycoRes+ PMID:9657149
PR:000044495 mTHBS1/SigPep- PMID:12498716