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Protein Ontology report - serine/threonine-protein kinase WNK1
PR:000017431 - http://purl.obolibrary.org/obo/PR_000017431
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000017431   
  PRO nameserine/threonine-protein kinase WNK1 
  Synonyms
PRO-Short-label: EXACT:WNK1
Gene-based: RELATED:HSN2 | KDP | KIAA0344 | PRKWNK1
Other: EXACT:erythrocyte 65 kDa protein | kinase deficient protein | protein kinase lysine-deficient 1 | protein kinase with no lysine 1
RELATED:protein HSN2
  Definition"A protein that is a translation product of the human WNK1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 18                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2280
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000017431
serine/threonine-protein kinase WNK1
WNK1
"A protein that is a translation product of the human WNK1 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P83741
serine/threonine-protein kinase WNK1 (mouse)
mWNK1
"A serine/threonine-protein kinase WNK1 that is encoded in the genome of mouse." [OMA:P83741, PRO:DNx]

organism-sequence


PR:P83741-1
serine/threonine-protein kinase WNK1 isoform m1 (mouse)
mWNK1/iso:m1
"A serine/threonine-protein kinase WNK1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P83741-1." [PMID:14514722, PRO:DAN, PRO:HJD]

organism-sequence


PR:P83741-2
serine/threonine-protein kinase WNK1, brain and spinal cord isoform (mouse)
mWNK1/iso:bsc
"A serine/threonine-protein kinase WNK1, brain and spinal cord isoform that is encoded in the genome of mouse." [PMID:18521183, PRO:HJD]

organism-sequence


PR:P83741-3
serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform (mouse)
mWNK1/iso:drgsn
"A serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform that is encoded in the genome of mouse." [PMID:18521183, PRO:HJD]

organism-sequence


PR:P83741-4
serine/threonine-protein kinase WNK1 isoform m4 (mouse)
mWNK1/iso:m4
"A serine/threonine-protein kinase WNK1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P83741-4. This form lacks the C-terminal region corresponding to residues 784 to 1032 of isoform 1." [PMID:15489334, PRO:HJD]

organism-sequence


PR:P83741-5
serine/threonine-protein kinase WNK1 isoform m5 (mouse)
mWNK1/iso:m5
"A serine/threonine-protein kinase WNK1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P83741-5." [PMID:15489334, PRO:HJD]

organism-sequence


PR:P83741-6
serine/threonine-protein kinase WNK1 isoform m6 (mouse)
mWNK1/iso:m6
"A serine/threonine-protein kinase WNK1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P83741-6. This form may arise due to intron retention." [PMID:15368895, PRO:HJD]

organism-sequence


PR:P83741-7
serine/threonine-protein kinase WNK1 isoform m7 (mouse)
mWNK1/iso:m7
"A serine/threonine-protein kinase WNK1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P83741-7." [PRO:DNx, UniProtKB:P83741]

organism-gene


PR:Q9H4A3
serine/threonine-protein kinase WNK1 (human)
hWNK1
"A serine/threonine-protein kinase WNK1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9H4A3]

organism-sequence


PR:Q9H4A3-1
serine/threonine-protein kinase WNK1 isoform h1 (human)
hWNK1/iso:h1
"A serine/threonine-protein kinase WNK1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H4A3-1." [PRO:DNx, UniProtKB:Q9H4A3]

organism-sequence


PR:Q9H4A3-2
serine/threonine-protein kinase WNK1 isoform h2 (human)
hWNK1/iso:h2
"A serine/threonine-protein kinase WNK1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H4A3-2." [PRO:DNx, UniProtKB:Q9H4A3]

organism-sequence


PR:Q9H4A3-4
serine/threonine-protein kinase WNK1, kidney-specific isoform (human)
hWNK1/iso:k
"A serine/threonine-protein kinase WNK1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H4A3-4." [PRO:DNx, UniProtKB:Q9H4A3]

organism-sequence


PR:Q9H4A3-5
serine/threonine-protein kinase WNK1 isoform h4 (human)
hWNK1/iso:h4
"A serine/threonine-protein kinase WNK1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H4A3-5." [PMID:15060842, PRO:CNA, PRO:DAN]

organism-sequence


PR:Q9H4A3-6
serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform (human)
hWNK1/iso:drgsn
"A serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform that is encoded in the genome of human." [PMID:15060842, PRO:CNA]

organism-sequence


PR:Q9H4A3-7
serine/threonine-protein kinase WNK1 isoform h6 (human)
hWNK1/iso:h6
"A serine/threonine-protein kinase WNK1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H4A3-7." [PRO:DNx, UniProtKB:Q9H4A3]

organism-modification


PR:000046059
serine/threonine-protein kinase WNK1 phosphorylated 1 (human)
hWNK1/Phos:1
"A serine/threonine-protein kinase WNK1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-60 of the amino acid sequence represented by UniProtKB:Q9H4A3-1. Example: UniProtKB:Q9H4A3-1, Thr-60, MOD:00047." [iPTMnet:Q9H4A3, PMID:14611643]

organism-modification


PR:000082086
serine/threonine-protein kinase WNK1 phosphorylated 2 (human)
hWNK1/Phos:2
"A serine/threonine-protein kinase WNK1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-378 of the amino acid sequence represented by UniProtKB:Q9H4A3-1. Example: UniProtKB:Q9H4A3-1, Ser-378, MOD:00046." [IEDB_epitope:846268, PRO:DNx]

organism-gene


PR:Q9JIH7
serine/threonine-protein kinase WNK1 (rat)
rWNK1
"A serine/threonine-protein kinase WNK1 that is encoded in the genome of rat." [OMA:Q9JIH7, PRO:DAN]

organism-sequence


PR:Q9JIH7-1
serine/threonine-protein kinase WNK1 isoform r1 (rat)
rWnk1/iso:r1
"A serine/threonine-protein kinase WNK1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JIH7-1." [PRO:DNx, UniProtKB:Q9JIH7]

organism-sequence


PR:Q9JIH7-2
serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform (rat)
rWNK1/iso:drgsn
"A serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform that is encoded in the genome of rat." [PRO:DAN]

organism-sequence


PR:Q9JIH7-3
serine/threonine-protein kinase WNK1, brain and spinal cord isoform (rat)
rWNK1/iso:bsc
"A serine/threonine-protein kinase WNK1, brain and spinal cord isoform that is encoded in the genome of rat." [PRO:DAN]

organism-sequence


PR:Q9JIH7-4
serine/threonine-protein kinase WNK1 isoform r4 (rat)
rWNK1/iso:r4
"A serine/threonine-protein kinase WNK1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JIH7-4." [PRO:DNx, UniProtKB:Q9JIH7]

organism-sequence


PR:Q9JIH7-5
serine/threonine-protein kinase WNK1 isoform r5 (rat)
rWNK1/iso:r5
"A serine/threonine-protein kinase WNK1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JIH7-5." [PRO:DNx, UniProtKB:Q9JIH7]

sequence


PR:000037199
serine/threonine-protein kinase WNK1, brain and spinal cord isoform
WNK1/iso:bsc
"A serine/threonine-protein kinase WNK1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P83741-2 or a 1:1 ortholog thereof. This form contains the region coded by the nervous system-specific exon HSN2 (as named in human and mouse)." [PMID:15060842, PMID:18521183, PRO:CNA]

organism-sequence


PR:P83741-2
serine/threonine-protein kinase WNK1, brain and spinal cord isoform (mouse)
mWNK1/iso:bsc
"A serine/threonine-protein kinase WNK1, brain and spinal cord isoform that is encoded in the genome of mouse." [PMID:18521183, PRO:HJD]

organism-sequence


PR:Q9JIH7-3
serine/threonine-protein kinase WNK1, brain and spinal cord isoform (rat)
rWNK1/iso:bsc
"A serine/threonine-protein kinase WNK1, brain and spinal cord isoform that is encoded in the genome of rat." [PRO:DAN]

sequence


PR:000037201
serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform
WNK1/iso:drgsn
"A serine/threonine-protein kinase WNK1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P83741-3 or a 1:1 ortholog thereof. This form contains the region coded by the nervous system-specific exon HSN2 (as named in human and mouse)." [PMID:15060842, PMID:18521183, PRO:HJD]

organism-sequence


PR:P83741-3
serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform (mouse)
mWNK1/iso:drgsn
"A serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform that is encoded in the genome of mouse." [PMID:18521183, PRO:HJD]

organism-sequence


PR:Q9H4A3-6
serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform (human)
hWNK1/iso:drgsn
"A serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform that is encoded in the genome of human." [PMID:15060842, PRO:CNA]

organism-sequence


PR:Q9JIH7-2
serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform (rat)
rWNK1/iso:drgsn
"A serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform that is encoded in the genome of rat." [PRO:DAN]