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Protein Ontology report - vascular endothelial growth factor C
PR:000017285 - http://purl.obolibrary.org/obo/PR_000017285
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000017285   
  PRO namevascular endothelial growth factor C 
  Synonyms
PRO-Short-label: EXACT:VEGFC
Other: EXACT:flt4 ligand | flt4-L | vascular endothelial growth factor-related protein | VEGF-C | VRP
  Definition"A protein that is a translation product of the human VEGFC gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence4                                                  Organism-Sequence 4                                        
         Modification2                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000017285

vascular endothelial growth factor C

VEGFC


"A protein that is a translation product of the human VEGFC gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O35757

vascular endothelial growth factor C (rat)

rVEGFC


"A vascular endothelial growth factor C that is encoded in the genome of rat." [OMA:O35757, PRO:DNx]


organism-gene



PR:P49767

vascular endothelial growth factor C (human)

hVEGFC


"A vascular endothelial growth factor C that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49767]


organism-modification



PR:000076094

vascular endothelial growth factor C, mature form (human)

hVEGFC/mature


"A vascular endothelial growth factor C (human) that has had the signal peptide and all propeptides removed. UniProtKB:P49767, 112-227." [PRO:DNx, Reactome:R-HSA-139887, Reactome:R-HSA-67159]


organism-gene



PR:P97953

vascular endothelial growth factor C (mouse)

mVEGFC


"A vascular endothelial growth factor C that is encoded in the genome of mouse." [OMA:P97953, PRO:DNx]


organism-sequence



PR:P97953-1

vascular endothelial growth factor C isoform 1 (mouse)

mVEGFC/iso:1


"A vascular endothelial growth factor C isoform 1 that is encoded in the genome of mouse." [PMID:9012504, PRO:HJD]

Yes

organism-sequence



PR:P97953-2

vascular endothelial growth factor C isoform 2 (mouse)

mVEGFC/iso:2


"A vascular endothelial growth factor C isoform 2 that is encoded in the genome of mouse." [PMID:20415667, PRO:HJD]


organism-sequence



PR:P97953-3

vascular endothelial growth factor C isoform 3 (mouse)

mVEGFC/iso:3


"A vascular endothelial growth factor C isoform 3 that is encoded in the genome of mouse." [PMID:20415667, PRO:HJD]


organism-sequence



PR:P97953-4

vascular endothelial growth factor C isoform 4 (mouse)

mVEGFC/iso:4


"A vascular endothelial growth factor C isoform 4 that is encoded in the genome of mouse." [PMID:20415667, PRO:HJD]


sequence



PR:000037102

vascular endothelial growth factor C isoform 1

VEGFC/iso:1


"A vascular endothelial growth factor C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97953-1 or a 1:1 ortholog thereof." [PMID:9012504, PRO:HJD]


organism-sequence



PR:P97953-1

vascular endothelial growth factor C isoform 1 (mouse)

mVEGFC/iso:1


"A vascular endothelial growth factor C isoform 1 that is encoded in the genome of mouse." [PMID:9012504, PRO:HJD]

Yes

sequence



PR:000037104

vascular endothelial growth factor C isoform 2

VEGFC/iso:2


"A vascular endothelial growth factor C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97953-2 or a 1:1 ortholog thereof." [PMID:9012504, PRO:HJD]


organism-sequence



PR:P97953-2

vascular endothelial growth factor C isoform 2 (mouse)

mVEGFC/iso:2


"A vascular endothelial growth factor C isoform 2 that is encoded in the genome of mouse." [PMID:20415667, PRO:HJD]


sequence



PR:000037106

vascular endothelial growth factor C isoform 3

VEGFC/iso:3


"A vascular endothelial growth factor C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97953-3 or a 1:1 ortholog thereof." [PMID:9012504, PRO:HJD]


organism-sequence



PR:P97953-3

vascular endothelial growth factor C isoform 3 (mouse)

mVEGFC/iso:3


"A vascular endothelial growth factor C isoform 3 that is encoded in the genome of mouse." [PMID:20415667, PRO:HJD]


sequence



PR:000037108

vascular endothelial growth factor C isoform 4

VEGFC/iso:4


"A vascular endothelial growth factor C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97953-4 or a 1:1 ortholog thereof." [PMID:9012504, PRO:HJD]


organism-sequence



PR:P97953-4

vascular endothelial growth factor C isoform 4 (mouse)

mVEGFC/iso:4


"A vascular endothelial growth factor C isoform 4 that is encoded in the genome of mouse." [PMID:20415667, PRO:HJD]


modification



PR:000021822

vascular endothelial growth factor C, signal peptide removed form

VEGFC/SigPep-


"A vascular endothelial growth factor C that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000076094

vascular endothelial growth factor C, mature form (human)

hVEGFC/mature


"A vascular endothelial growth factor C (human) that has had the signal peptide and all propeptides removed. UniProtKB:P49767, 112-227." [PRO:DNx, Reactome:R-HSA-139887, Reactome:R-HSA-67159]


modification



PR:000021823

vascular endothelial growth factor C proteolytic cleavage product

VEGFC/ClvPrd


"A vascular endothelial growth factor C that has been processed by proteolytic cleavage." [PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P97953-1 mVEGFC/iso:1 acts_upstream_of_or_withinGO:0001954 positive regulation of cell-matrix adhesion MGI_ref:4820931; PMID:20415667
GO:0008285 negative regulation of cell population proliferation MGI_ref:4820931; PMID:20415667
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation MGI_ref:4820931; PMID:20415667
enablesGO:0005515 protein binding with PR:P09405 mNCL MGI_ref:4820931; PMID:20415667