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Protein Ontology report - regulator of nonsense transcripts 1
PR:000017108 - http://purl.obolibrary.org/obo/PR_000017108
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000017108   
  PRO nameregulator of nonsense transcripts 1 
  Synonyms
PRO-Short-label: EXACT:UPF1
Gene-based: RELATED:KIAA0221 | RENT1
Other: EXACT:ATP-dependent helicase RENT1 | nonsense mRNA reducing factor 1 | NORF1 | up-frameshift suppressor 1 homolog | Upf1
  Definition"A protein that is a translation product of the human UPF1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 9                                        
         Sequence2                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 10                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000017108
regulator of nonsense transcripts 1
UPF1
"A protein that is a translation product of the human UPF1 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:F1RCY6
regulator of nonsense transcripts 1 (zebrafish)
z-UPF1
"A regulator of nonsense transcripts 1 that is encoded in the genome of zebrafish." [OMA:F1RCY6, PRO:DNx]

organism-gene


PR:O76512
regulator of nonsense transcripts 1 (worm)
UPF1 (worm)
"A regulator of nonsense transcripts 1 that is encoded in the genome of worm." [OMA:O76512, PRO:DNx]

organism-gene


PR:P30771
ATP-dependent helicase NAM7 (yeast)
yUPF1
"A regulator of nonsense transcripts 1 that is encoded in the genome of yeast." [OMA:P30771, PRO:DNx]

organism-gene


PR:Q09820
ATP-dependent helicase upf1 (Schizosaccharomyces pombe 972h-)
Spom972h-UPF1
"A regulator of nonsense transcripts 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q09820, PRO:DNx]

organism-gene


PR:Q54I89
regulator of nonsense transcripts 1 (Dictyostelium discoideum)
Dicty-UPF1
"A regulator of nonsense transcripts 1 that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54I89, PRO:DNx]

organism-gene


PR:Q92900
regulator of nonsense transcripts 1 (human)
hUPF1
"A regulator of nonsense transcripts 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q92900]

organism-sequence


PR:Q92900-1
regulator of nonsense transcripts 1 isoform 1 (human)
hUPF1/iso:1
"A regulator of nonsense transcripts 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]

organism-sequence


PR:Q92900-2
regulator of nonsense transcripts 1 isoform 2 (human)
hUPF1/iso:2
"A regulator of nonsense transcripts 1 isoform 2 that is encoded in the genome of human." [PMID:18423202]
Yes
organism-modification


PR:000049622
regulator of nonsense transcripts 1 phosphorylated 1 (human)
hUPF1/Phos:1
"A regulator of nonsense transcripts 1 (human) that has been post-translationally modified to include phosphoserine at positions 1084, 1089, 1107 and 1127 of the amino acid sequence represented by UniProtKB:Q92900. UniProtKB:Q92900, Ser-1084/Ser-1089/Ser-1107/Ser-1127, MOD:00046." [PRO:DNx, Reactome:R-HSA-927856]

organism-modification


PR:000071124
regulator of nonsense transcripts 1 deaminated 1 (human)
hUPF1/Deam:1
"A regulator of nonsense transcripts 1 (human) that has been deaminated on the residue at the position equivalent to Gln-260 of the amino acid sequence represented by UniProtKB:Q92900-1. Example: UniProtKB:Q92900-1, Gln-260, MOD:00685." [IEDB_epitope:838619, PRO:DNx]

organism-modification


PR:000072368
regulator of nonsense transcripts 1 cysteinylated 1 (human)
hUPF1/Cyst:1
"A regulator of nonsense transcripts 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-123 of the amino acid sequence represented by UniProtKB:Q92900-1. Example: UniProtKB:Q92900-1, Cys-123, MOD:00765." [IEDB_epitope:933177, PRO:DNx]

organism-modification


PR:000072759
regulator of nonsense transcripts 1 cysteinylated 2 (human)
hUPF1/Cyst:2
"A regulator of nonsense transcripts 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-374 of the amino acid sequence represented by UniProtKB:Q92900-1. Example: UniProtKB:Q92900-1, Cys-374, MOD:00765." [IEDB_epitope:636317, PRO:DNx]

organism-modification


PR:000073311
regulator of nonsense transcripts 1 deaminated 2 (human)
hUPF1/Deam:2
"A regulator of nonsense transcripts 1 (human) that has been deaminated on the residue at the position equivalent to Gln-810 of the amino acid sequence represented by UniProtKB:Q92900-1. Example: UniProtKB:Q92900-1, Gln-810, MOD:00685." [IEDB_epitope:1373717, PRO:DNx]

organism-modification


PR:000074861
regulator of nonsense transcripts 1 methylated 1 (human)
hUPF1/Me:1
"A regulator of nonsense transcripts 1 (human) that has been methylated on the residue at the position equivalent to Cys-657 of the amino acid sequence represented by UniProtKB:Q92900-1. Example: UniProtKB:Q92900-1, Cys-657, MOD:00660." [IEDB_epitope:1036728, PRO:DNx]

organism-modification


PR:000076607
regulator of nonsense transcripts 1 methylated 2 (human)
hUPF1/Me:2
"A regulator of nonsense transcripts 1 (human) that has been methylated on the residue at the position equivalent to Cys-374 of the amino acid sequence represented by UniProtKB:Q92900-1. Example: UniProtKB:Q92900-1, Cys-374, MOD:00660." [IEDB_epitope:1043191, PRO:DNx]

organism-modification


PR:000080473
regulator of nonsense transcripts 1 methylated 3 (human)
hUPF1/Me:3
"A regulator of nonsense transcripts 1 (human) that has been methylated on the residue at the position equivalent to Cys-165 of the amino acid sequence represented by UniProtKB:Q92900-1. Example: UniProtKB:Q92900-1, Cys-165, MOD:00660." [IEDB_epitope:1032463, PRO:DNx]

organism-modification


PR:000080541
regulator of nonsense transcripts 1 methylated 4 (human)
hUPF1/Me:4
"A regulator of nonsense transcripts 1 (human) that has been methylated on the residue at the position equivalent to Cys-683 of the amino acid sequence represented by UniProtKB:Q92900-1. Example: UniProtKB:Q92900-1, Cys-683, MOD:00660." [IEDB_epitope:1038525, PRO:DNx]

organism-modification


PR:000083032
regulator of nonsense transcripts 1 deaminated 3 (human)
hUPF1/Deam:3
"A regulator of nonsense transcripts 1 (human) that has been deaminated on the residue at the position equivalent to Gln-290 of the amino acid sequence represented by UniProtKB:Q92900-1. Example: UniProtKB:Q92900-1, Gln-290, MOD:00685." [IEDB_epitope:771835, PRO:DNx]

organism-gene


PR:Q9EPU0
regulator of nonsense transcripts 1 (mouse)
mUPF1
"A regulator of nonsense transcripts 1 that is encoded in the genome of mouse." [OMA:Q9EPU0, PRO:DNx]

organism-sequence


PR:Q9EPU0-1
regulator of nonsense transcripts 1 isoform 1 (mouse)
mUPF1/iso:1
"A regulator of nonsense transcripts 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

organism-sequence


PR:Q9EPU0-2
regulator of nonsense transcripts 1 isoform 2 (mouse)
mUPF1/iso:2
"A regulator of nonsense transcripts 1 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]

organism-gene


PR:Q9FJR0
regulator of nonsense transcripts 1 homolog (Arabidopsis thaliana)
At-UPF1
"A regulator of nonsense transcripts 1 that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9FJR0, PRO:DNx]

organism-gene


PR:Q9VYS3
regulator of nonsense transcripts 1 homolog (fruit fly)
fly-UPF1
"A regulator of nonsense transcripts 1 that is encoded in the genome of fruit fly." [OMA:Q9VYS3, PRO:DNx]

sequence


PR:000026502
regulator of nonsense transcripts 1 isoform 1
UPF1/iso:1
"A regulator of nonsense transcripts 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92900-1 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:Q92900-1
regulator of nonsense transcripts 1 isoform 1 (human)
hUPF1/iso:1
"A regulator of nonsense transcripts 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]

organism-sequence


PR:Q9EPU0-1
regulator of nonsense transcripts 1 isoform 1 (mouse)
mUPF1/iso:1
"A regulator of nonsense transcripts 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

sequence


PR:000026504
regulator of nonsense transcripts 1 isoform 2
UPF1/iso:2
"A regulator of nonsense transcripts 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92900-2 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:Q92900-2
regulator of nonsense transcripts 1 isoform 2 (human)
hUPF1/iso:2
"A regulator of nonsense transcripts 1 isoform 2 that is encoded in the genome of human." [PMID:18423202]
Yes
organism-sequence


PR:Q9EPU0-2
regulator of nonsense transcripts 1 isoform 2 (mouse)
mUPF1/iso:2
"A regulator of nonsense transcripts 1 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q92900-2 hUPF1/iso:2 enablesGO:0005515 protein binding with PR:Q14152 eIF-3-theta (human) PMID:18423202