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Protein Ontology report - thiopurine S-methyltransferase
PR:000016583 - http://purl.obolibrary.org/obo/PR_000016583
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000016583   
  PRO namethiopurine S-methyltransferase 
  Synonyms
PRO-Short-label: EXACT:TPMT
Other: EXACT:thiopurine methyltransferase
  Definition"A protein that is a translation product of the human TPMT gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000016583

thiopurine S-methyltransferase

TPMT


"A protein that is a translation product of the human TPMT gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O55060

thiopurine S-methyltransferase (mouse)

mTPMT


"A thiopurine S-methyltransferase that is encoded in the genome of mouse." [OMA:O55060, PRO:DNx]


organism-gene



PR:P51580

thiopurine S-methyltransferase (human)

hTPMT


"A thiopurine S-methyltransferase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P51580]


organism-sequence



PR:000061398

thiopurine S-methyltransferase sequence variant A167G (human)

hTPMT/var:A167G


"A thiopurine S-methyltransferase (human) that has a Gly residue at the position equivalent to Ala-167 of the amino acid sequence represented by UniProtKB:P51580. UniProtKB:P51580, Ala-167, CHEBI:29947." [PRO:DNx, Reactome:R-HSA-5603357]


organism-sequence



PR:000061449

thiopurine S-methyltransferase sequence variant A154T (human)

hTPMT/var:A154T


"A thiopurine S-methyltransferase (human) that has a Thr residue at the position equivalent to Ala-154 of the amino acid sequence represented by UniProtKB:P51580. UniProtKB:P51580, Ala-154, CHEBI:30013." [PRO:DNx, Reactome:R-HSA-5603333]


organism-sequence



PR:000062262

thiopurine S-methyltransferase sequence variant Y240C (human)

hTPMT/var:Y240C


"A thiopurine S-methyltransferase (human) that has a Cys residue at the position equivalent to Tyr-240 of the amino acid sequence represented by UniProtKB:P51580. UniProtKB:P51580, Tyr-240, CHEBI:29950." [PRO:DNx, Reactome:R-HSA-5603343]


organism-sequence



PR:000064030

thiopurine S-methyltransferase sequence variant A80P (human)

hTPMT/var:A80P


"A thiopurine S-methyltransferase (human) that has a Pro residue at the position equivalent to Ala-80 of the amino acid sequence represented by UniProtKB:P51580. UniProtKB:P51580, Ala-80, CHEBI:50342." [PRO:DNx, Reactome:R-HSA-5603346]


organism-modification



PR:000072859

thiopurine S-methyltransferase cysteinylated 1 (human)

hTPMT/Cyst:1


"A thiopurine S-methyltransferase (human) that has been cysteinylated on the residue at the position equivalent to Cys-70 of the amino acid sequence represented by UniProtKB:P51580. UniProtKB:P51580, Cys-70, MOD:00765." [IEDB_epitope:636524, PRO:DNx]


organism-modification



PR:000074148

thiopurine S-methyltransferase methylated 1 (human)

hTPMT/Me:1


"A thiopurine S-methyltransferase (human) that has been methylated on the residue at the position equivalent to Cys-70 of the amino acid sequence represented by UniProtKB:P51580. UniProtKB:P51580, Cys-70, MOD:00660." [IEDB_epitope:1046556, PRO:DNx]


organism-gene



PR:Q504A5

probable thiopurine S-methyltransferase (zebrafish)

z-TPMT


"A thiopurine S-methyltransferase that is encoded in the genome of zebrafish." [PRO:DNx]


organism-gene



PR:Q9Z0T0

thiopurine S-methyltransferase (rat)

rTPMT


"A thiopurine S-methyltransferase that is encoded in the genome of rat." [OMA:Q9Z0T0, PRO:DNx]