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Protein Ontology report - Toll-interacting protein
PR:000016528 - http://purl.obolibrary.org/obo/PR_000016528
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000016528   
  PRO nameToll-interacting protein 
  Synonyms
PRO-Short-label: EXACT:TOLLIP
  Definition"A protein that is a translation product of the human TOLLIP gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence1                                                  Organism-Sequence 3                                        
         Modification1                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000016528

Toll-interacting protein

TOLLIP


"A protein that is a translation product of the human TOLLIP gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:A2RUW1

Toll-interacting protein (rat)

rTOLLIP


"A Toll-interacting protein that is encoded in the genome of rat." [OMA:A2RUW1, PRO:DNx]


organism-gene



PR:Q5ZK05

Toll-interacting protein (chicken)

chick-TOLLIP


"A Toll-interacting protein that is encoded in the genome of chicken." [OMA:Q5ZK05, PRO:DNx]


organism-gene



PR:Q7ZV43

Toll-interacting protein (zebrafish)

z-TOLLIP


"A Toll-interacting protein that is encoded in the genome of zebrafish." [OMA:Q7ZV43, PRO:DNx]


organism-gene



PR:Q9H0E2

Toll-interacting protein (human)

hTOLLIP


"A Toll-interacting protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9H0E2]


organism-sequence



PR:Q9H0E2-1

Toll-interacting protein isoform 1 (human)

hTOLLIP/iso:1


"A Toll-interacting protein isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q9H0E2-2

Toll-interacting protein isoform h2 (human)

hTOLLIP/iso:h2


"A Toll-interacting protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H0E2-2." [PRO:DNx, UniProtKB:Q9H0E2]


organism-gene



PR:Q9QZ06

Toll-interacting protein (mouse)

mTOLLIP


"A Toll-interacting protein that is encoded in the genome of mouse." [OMA:Q9QZ06, PRO:DNx]


organism-sequence



PR:Q9QZ06-1

Toll-interacting protein isoform 1 (mouse)

mTOLLIP/iso:1


"A Toll-interacting protein isoform 1 that is encoded in the genome of mouse." [PMID:10854325, PRO:CNA]

Yes

Yes
sequence



PR:000027250

Toll-interacting protein isoform 1

TOLLIP/iso:1


"A Toll-interacting protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QZ06-1 or a 1:1 ortholog thereof." [PMID:10854325, PRO:CNA]


organism-sequence



PR:Q9H0E2-1

Toll-interacting protein isoform 1 (human)

hTOLLIP/iso:1


"A Toll-interacting protein isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q9QZ06-1

Toll-interacting protein isoform 1 (mouse)

mTOLLIP/iso:1


"A Toll-interacting protein isoform 1 that is encoded in the genome of mouse." [PMID:10854325, PRO:CNA]

Yes

Yes
modification



PR:000021716

Toll-interacting protein, initiator methionine removed form

TOLLIP/InitMet-


"A Toll-interacting protein that has had the initiator methionine removed." [PRO:DNx]


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TOLLIP forms found in complexes   

TOLLIP Component
Complexes
PR:Q9QZ06ZDASHZ1 mTOLLIP/iso:1 PR:000027253 IRAK1:tollip complex (mouse)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9QZ06-1 mTOLLIP/iso:1 acts_upstream_of_or_withinGO:0006954 inflammatory response PMID:10854325
GO:0034122 negative regulation of toll-like receptor signaling pathway PMID:10854325