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Protein Ontology report - transcription factor AP-2-alpha
PR:000016263 - http://purl.obolibrary.org/obo/PR_000016263
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000016263   
  PRO nametranscription factor AP-2-alpha 
  Synonyms
PRO-Short-label: EXACT:TFAP2A
Gene-based: RELATED:AP2TF | Tcfap2a | TFAP2
Other: EXACT:activating enhancer-binding protein 2-alpha | activator protein 2 | AP-2 | AP-2 transcription factor | AP2-alpha
  Definition"A protein that is a translation product of the human TFAP2A gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence3                                                  Organism-Sequence 8                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000016263
transcription factor AP-2-alpha
TFAP2A
"A protein that is a translation product of the human TFAP2A gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P05549
transcription factor AP-2-alpha (human)
hTFAP2A
"A transcription factor AP-2-alpha that is encoded in the genome of human." [PRO:DNx, UniProtKB:P05549]

organism-sequence


PR:P05549-1
transcription factor AP-2-alpha isoform 1 (human)
hTFAP2A/iso:1
"A transcription factor AP-2-alpha isoform 1 that is encoded in the genome of human." [PRO:AAA, UniProtKB:P05549-1]
Yes
organism-modification


PR:000064675
transcription factor AP-2-alpha isoform 1 sumoylated 1 (human)
hTFAP2A/iso:1/Sumo:1
"A transcription factor AP-2-alpha isoform 1 (human) that has been sumoylated on the residue at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:P05549-1. UniProtKB:P05549-1, Lys-10, MOD:01149." [PRO:DNx, Reactome:R-HSA-3234080]

organism-sequence


PR:P05549-2
transcription factor AP-2-alpha isoform 4 (human)
hTFAP2A/iso:4
"A transcription factor AP-2-alpha isoform 4 that is encoded in the genome of human." [PRO:AAA, UniProtKB:P05549-2]
Yes
organism-sequence


PR:P05549-5
transcription factor AP-2-alpha isoform 2 (human)
hTFAP2A/iso:2
"A transcription factor AP-2-alpha isoform 5 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:P05549-6
transcription factor AP-2-alpha isoform h5 (human)
hTFAP2A/iso:h5
"A transcription factor AP-2-alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05549-6." [PRO:DNx, UniProtKB:P05549]

organism-gene


PR:P34056
transcription factor AP-2-alpha (mouse)
mTFAP2A
"A transcription factor AP-2-alpha that is encoded in the genome of mouse." [OMA:P34056, PRO:DNx]

organism-sequence


PR:P34056-1
transcription factor AP-2-alpha isoform m1 (mouse)
mTFAP2A/iso:m1
"A transcription factor AP-2-alpha (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34056-1." [PRO:DNx, UniProtKB:P34056]

organism-sequence


PR:P34056-2
transcription factor AP-2-alpha isoform m2 (mouse)
mTFAP2A/iso:m2
"A transcription factor AP-2-alpha (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34056-2." [PRO:DNx, UniProtKB:P34056]

organism-sequence


PR:P34056-3
transcription factor AP-2-alpha isoform 3 (mouse)
mTFAP2A/iso:3
"A transcription factor AP-2-alpha isoform 5 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:P34056-4
transcription factor AP-2-alpha isoform m4 (mouse)
mTFAP2A/iso:m4
"A transcription factor AP-2-alpha (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34056-4." [PRO:DNx, UniProtKB:P34056]

organism-gene


PR:P58197
transcription factor AP-2-alpha (rat)
rTFAP2A
"A transcription factor AP-2-alpha that is encoded in the genome of rat." [OMA:P58197, PRO:DNx]

sequence


PR:000035491
transcription factor AP-2-alpha isoform 1
TFAP2A/iso:1
"A transcription factor AP-2-alpha that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05549-1 or a 1:1 ortholog thereof." [PRO:AAA, UniProtKB:P05549-1]

organism-sequence


PR:P05549-1
transcription factor AP-2-alpha isoform 1 (human)
hTFAP2A/iso:1
"A transcription factor AP-2-alpha isoform 1 that is encoded in the genome of human." [PRO:AAA, UniProtKB:P05549-1]
Yes
organism-modification


PR:000064675
transcription factor AP-2-alpha isoform 1 sumoylated 1 (human)
hTFAP2A/iso:1/Sumo:1
"A transcription factor AP-2-alpha isoform 1 (human) that has been sumoylated on the residue at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:P05549-1. UniProtKB:P05549-1, Lys-10, MOD:01149." [PRO:DNx, Reactome:R-HSA-3234080]

sequence


PR:000035493
transcription factor AP-2-alpha isoform 4
TFAP2A/iso:4
"A transcription factor AP-2-alpha that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05549-2 or a 1:1 ortholog thereof." [PRO:AAA, UniProtKB:P05549-2]

organism-sequence


PR:P05549-2
transcription factor AP-2-alpha isoform 4 (human)
hTFAP2A/iso:4
"A transcription factor AP-2-alpha isoform 4 that is encoded in the genome of human." [PRO:AAA, UniProtKB:P05549-2]
Yes
sequence


PR:000038681
transcription factor AP-2-alpha isoform 5
TFAP2A/iso:5
"A transcription factor AP-2-alpha that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05549-5 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P05549-5
transcription factor AP-2-alpha isoform 2 (human)
hTFAP2A/iso:2
"A transcription factor AP-2-alpha isoform 5 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:P34056-3
transcription factor AP-2-alpha isoform 3 (mouse)
mTFAP2A/iso:3
"A transcription factor AP-2-alpha isoform 5 that is encoded in the genome of mouse." [PRO:DNx]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P05549-1 hTFAP2A/iso:1 acts_upstream_of_or_withinGO:0045944 positive regulation of transcription by RNA polymerase II PMID:8321221
PR:P05549-2 hTFAP2A/iso:4 acts_upstream_of_or_withinGO:0000122 negative regulation of transcription by RNA polymerase II PMID:8321221