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Protein Ontology report - nesprin-2
PR:000015876 - http://purl.obolibrary.org/obo/PR_000015876
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000015876   
  PRO namenesprin-2 
  Synonyms
PRO-Short-label: EXACT:SYNE2
Gene-based: RELATED:KIAA1011 | NUA
Other: EXACT:KASH domain-containing protein 2 | KASH2 | nuclear envelope spectrin repeat protein 2 | nucleus and actin connecting element protein | protein NUANCE | synaptic nuclear envelope protein 2 | Syne-2
  Definition"A protein that is a translation product of the human SYNE2 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence5                                                  Organism-Sequence 16                                        
         Modification0                                                  Organism-Modification 17                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000015876

nesprin-2

SYNE2


"A protein that is a translation product of the human SYNE2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:M9MRD1

muscle-specific protein 300 kDa (fruit fly)

fly-SYNE2


"A nesprin-2 that is encoded in the genome of fruit fly." [PRO:DNx]


organism-gene



PR:Q6ZWQ0

nesprin-2 (mouse)

mSYNE2


"A nesprin-2 that is encoded in the genome of mouse." [OMA:Q6ZWQ0, PRO:DNx]


organism-sequence



PR:Q6ZWQ0-1

nesprin-2 isoform m1 (mouse)

mSYNE2/iso:m1


"A nesprin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZWQ0-1." [PRO:DNx, UniProtKB:Q6ZWQ0]


organism-sequence



PR:Q6ZWQ0-2

nesprin-2 isoform m2 (mouse)

mSYNE2/iso:m2


"A nesprin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZWQ0-2." [PRO:DNx, UniProtKB:Q6ZWQ0]


organism-sequence



PR:Q6ZWQ0-3

nesprin-2 isoform m3 (mouse)

mSYNE2/iso:m3


"A nesprin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZWQ0-3." [PRO:DNx, UniProtKB:Q6ZWQ0]


organism-gene



PR:Q8WXH0

nesprin-2 (human)

hSYNE2


"A nesprin-2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8WXH0]


organism-sequence



PR:Q8WXH0-1

nesprin-2 isoform 1 (human)

hSYNE2/iso:1


"A nesprin-2 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q8WXH0-10

nesprin-2 isoform h10 (human)

hSYNE2/iso:h10


"A nesprin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-10." [PRO:DNx, UniProtKB:Q8WXH0]


organism-sequence



PR:Q8WXH0-11

nesprin-2 isoform h11 (human)

hSYNE2/iso:h11


"A nesprin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-11." [PRO:DNx, UniProtKB:Q8WXH0]


organism-sequence



PR:Q8WXH0-12

nesprin-2 isoform h12 (human)

hSYNE2/iso:h12


"A nesprin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-12." [PRO:DNx, UniProtKB:Q8WXH0]


organism-sequence



PR:Q8WXH0-13

nesprin-2 isoform h13 (human)

hSYNE2/iso:h13


"A nesprin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-13." [PRO:DNx, UniProtKB:Q8WXH0]


organism-sequence



PR:Q8WXH0-2

nesprin-2 isoform 2 (human)

hSYNE2/iso:2


"A nesprin-2 isoform 2 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q8WXH0-3

nesprin-2 isoform 3 (human)

hSYNE2/iso:3


"A nesprin-2 isoform 3 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q8WXH0-4

nesprin-2 isoform 4 (human)

hSYNE2/iso:4


"A nesprin-2 isoform 4 that is encoded in the genome of human." [PMID:19933576]

Yes

organism-sequence



PR:Q8WXH0-5

nesprin-2 isoform 5 (human)

hSYNE2/iso:5


"A nesprin-2 isoform 5 that is encoded in the genome of human." [PMID:19933576]

Yes

organism-sequence



PR:Q8WXH0-6

nesprin-2 isoform h6 (human)

hSYNE2/iso:h6


"A nesprin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-6." [PRO:DNx, UniProtKB:Q8WXH0]


organism-sequence



PR:Q8WXH0-7

nesprin-2 isoform h7 (human)

hSYNE2/iso:h7


"A nesprin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-7." [PRO:DNx, UniProtKB:Q8WXH0]


organism-sequence



PR:Q8WXH0-8

nesprin-2 isoform h8 (human)

hSYNE2/iso:h8


"A nesprin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-8." [PRO:DNx, UniProtKB:Q8WXH0]


organism-sequence



PR:Q8WXH0-9

nesprin-2 isoform h9 (human)

hSYNE2/iso:h9


"A nesprin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-9." [PRO:DNx, UniProtKB:Q8WXH0]


organism-modification



PR:000067135

nesprin-2 phosphorylated 1 (human)

hSYNE2/Phos:1


"A nesprin-2 (human) that has been phosphorylated on the residue at the position equivalent to Ser-3915 of the amino acid sequence represented by UniProtKB:Q8WXH0-1. Example: UniProtKB:Q8WXH0-1, Ser-3915, MOD:00046." [IEDB_epitope:1372884, PRO:DNx]


organism-modification



PR:000067285

nesprin-2 methylated 1 (human)

hSYNE2/Me:1


"A nesprin-2 (human) that has been methylated on the residue at the position equivalent to Cys-982 of the amino acid sequence represented by UniProtKB:Q8WXH0-1. Example: UniProtKB:Q8WXH0-1, Cys-982, MOD:00660." [IEDB_epitope:1029553, PRO:DNx]


organism-modification



PR:000067968

nesprin-2 deaminated 1 (human)

hSYNE2/Deam:1


"A nesprin-2 (human) that has been deaminated on the residue at the position equivalent to Gln-4794 of the amino acid sequence represented by UniProtKB:Q8WXH0-1. Example: UniProtKB:Q8WXH0-1, Gln-4794, MOD:00685." [IEDB_epitope:1565104, PRO:DNx]


organism-modification



PR:000068976

nesprin-2 deaminated 2 (human)

hSYNE2/Deam:2


"A nesprin-2 (human) that has been deaminated on the residue at the position equivalent to Asn-340 of the amino acid sequence represented by UniProtKB:Q8WXH0-1. Example: UniProtKB:Q8WXH0-1, Asn-340, MOD:00684." [IEDB_epitope:1324410, PRO:DNx]


organism-modification



PR:000069007

nesprin-2 deaminated 3 (human)

hSYNE2/Deam:3


"A nesprin-2 (human) that has been deaminated on the residue at the position equivalent to Gln-1041 of the amino acid sequence represented by UniProtKB:Q8WXH0-1. Example: UniProtKB:Q8WXH0-1, Gln-1041, MOD:00685." [IEDB_epitope:838690, PRO:DNx]


organism-modification



PR:000069321

nesprin-2 deaminated 4 (human)

hSYNE2/Deam:4


"A nesprin-2 (human) that has been deaminated on the residue at the position equivalent to Asn-3758 of the amino acid sequence represented by UniProtKB:Q8WXH0-1. Example: UniProtKB:Q8WXH0-1, Asn-3758, MOD:00684." [IEDB_epitope:1582095, PRO:DNx]


organism-modification



PR:000069549

nesprin-2 deaminated 5 (human)

hSYNE2/Deam:5


"A nesprin-2 (human) that has been deaminated on the residue at the position equivalent to Asn-4684 of the amino acid sequence represented by UniProtKB:Q8WXH0-1. Example: UniProtKB:Q8WXH0-1, Asn-4684, MOD:00684." [IEDB_epitope:1998206, PRO:DNx]


organism-modification



PR:000070439

nesprin-2 cysteinylated 1 (human)

hSYNE2/Cyst:1


"A nesprin-2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-568 of the amino acid sequence represented by UniProtKB:Q8WXH0-1. Example: UniProtKB:Q8WXH0-1, Cys-568, MOD:00765." [IEDB_epitope:1581078, PRO:DNx]


organism-modification



PR:000070710

nesprin-2 cysteinylated 2 (human)

hSYNE2/Cyst:2


"A nesprin-2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-982 of the amino acid sequence represented by UniProtKB:Q8WXH0-1. Example: UniProtKB:Q8WXH0-1, Cys-982, MOD:00765." [IEDB_epitope:928619, PRO:DNx]


organism-modification



PR:000072041

nesprin-2 deaminated 6 (human)

hSYNE2/Deam:6


"A nesprin-2 (human) that has been deaminated on the residue at the position equivalent to Asn-3869 of the amino acid sequence represented by UniProtKB:Q8WXH0-1. Example: UniProtKB:Q8WXH0-1, Asn-3869, MOD:00684." [IEDB_epitope:2141380, PRO:DNx]


organism-modification



PR:000072395

nesprin-2 deaminated 7 (human)

hSYNE2/Deam:7


"A nesprin-2 (human) that has been deaminated on the residue at the position equivalent to Asn-2707 of the amino acid sequence represented by UniProtKB:Q8WXH0-1. Example: UniProtKB:Q8WXH0-1, Asn-2707, MOD:00684." [IEDB_epitope:1984809, PRO:DNx]


organism-modification



PR:000073502

nesprin-2 deaminated 8 (human)

hSYNE2/Deam:8


"A nesprin-2 (human) that has been deaminated on the residue at the position equivalent to Asn-202 of the amino acid sequence represented by UniProtKB:Q8WXH0-1. Example: UniProtKB:Q8WXH0-1, Asn-202, MOD:00684." [IEDB_epitope:1333054, PRO:DNx]


organism-modification



PR:000076681

nesprin-2 deaminated 9 (human)

hSYNE2/Deam:9


"A nesprin-2 (human) that has been deaminated on the residue at the position equivalent to Gln-418 of the amino acid sequence represented by UniProtKB:Q8WXH0-1. Example: UniProtKB:Q8WXH0-1, Gln-418, MOD:00685." [IEDB_epitope:1976052, PRO:DNx]


organism-modification



PR:000078840

nesprin-2 deaminated 10 (human)

hSYNE2/Deam:10


"A nesprin-2 (human) that has been deaminated on the residue at the position equivalent to Gln-365 of the amino acid sequence represented by UniProtKB:Q8WXH0-1. Example: UniProtKB:Q8WXH0-1, Gln-365, MOD:00685." [IEDB_epitope:1985879, PRO:DNx]


organism-modification



PR:000083160

nesprin-2 deaminated 11 (human)

hSYNE2/Deam:11


"A nesprin-2 (human) that has been deaminated on the residue at the position equivalent to Asn-952 of the amino acid sequence represented by UniProtKB:Q8WXH0-1. Example: UniProtKB:Q8WXH0-1, Asn-952, MOD:00684." [IEDB_epitope:1988299, PRO:DNx]


organism-modification



PR:000084832

nesprin-2 methylated 2 (human)

hSYNE2/Me:2


"A nesprin-2 (human) that has been methylated on the residue at the position equivalent to Cys-1275 of the amino acid sequence represented by UniProtKB:Q8WXH0-1. Example: UniProtKB:Q8WXH0-1, Cys-1275, MOD:00660." [IEDB_epitope:1026092, PRO:DNx]


organism-modification



PR:000085025

nesprin-2 deaminated 12 (human)

hSYNE2/Deam:12


"A nesprin-2 (human) that has been deaminated on the residue at the position equivalent to Gln-5035 of the amino acid sequence represented by UniProtKB:Q8WXH0-1. Example: UniProtKB:Q8WXH0-1, Gln-5035, MOD:00685." [IEDB_epitope:902756, PRO:DNx]


organism-gene



PR:Q9N4M4

nuclear anchorage protein 1 (worm)

SYNE2 (worm)


"A nesprin-2 that is encoded in the genome of worm." [PRO:DNx]


sequence



PR:000026482

nesprin-2 isoform 1

SYNE2/iso:1


"A nesprin-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:Q8WXH0-1

nesprin-2 isoform 1 (human)

hSYNE2/iso:1


"A nesprin-2 isoform 1 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000026484

nesprin-2 isoform 2

SYNE2/iso:2


"A nesprin-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-2 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:Q8WXH0-2

nesprin-2 isoform 2 (human)

hSYNE2/iso:2


"A nesprin-2 isoform 2 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000026486

nesprin-2 isoform 3

SYNE2/iso:3


"A nesprin-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-3 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:Q8WXH0-3

nesprin-2 isoform 3 (human)

hSYNE2/iso:3


"A nesprin-2 isoform 3 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000026488

nesprin-2 isoform 4

SYNE2/iso:4


"A nesprin-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-4 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:Q8WXH0-4

nesprin-2 isoform 4 (human)

hSYNE2/iso:4


"A nesprin-2 isoform 4 that is encoded in the genome of human." [PMID:19933576]

Yes

sequence



PR:000026490

nesprin-2 isoform 5

SYNE2/iso:5


"A nesprin-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-5 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:Q8WXH0-5

nesprin-2 isoform 5 (human)

hSYNE2/iso:5


"A nesprin-2 isoform 5 that is encoded in the genome of human." [PMID:19933576]

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q8WXH0-4 hSYNE2/iso:4 enablesGO:0005515 protein binding with PR:Q9D666 mSUN1 PMID:19933576
PR:Q8WXH0-5 hSYNE2/iso:5 enablesGO:0005515 protein binding with PR:Q9D666 mSUN1 PMID:19933576
GO:0005515 protein binding with PR:Q9UH99 FRIGG PMID:19933576