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Protein Ontology report - STE20/SPS1-related proline-alanine-rich protein kinase
PR:000015756 - http://purl.obolibrary.org/obo/PR_000015756
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000015756   
  PRO nameSTE20/SPS1-related proline-alanine-rich protein kinase 
  Synonyms
PRO-Short-label: EXACT:STK39
Gene-based: RELATED:PASK | SPAK
Other: EXACT:DCHT | serine/threonine-protein kinase 39 | Ste-20-related kinase
  Definition"A protein that is a translation product of the human STK39 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence0                                                  Organism-Sequence 5                                        
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2224
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000015756

STE20/SPS1-related proline-alanine-rich protein kinase

STK39


"A protein that is a translation product of the human STK39 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O88506

STE20/SPS1-related proline-alanine-rich protein kinase (rat)

rSTK39


"A STE20/SPS1-related proline-alanine-rich protein kinase that is encoded in the genome of rat." [OMA:O88506, PRO:DNx]


organism-gene



PR:Q12701

serine/threonine-protein kinase ksg1 (Schizosaccharomyces pombe 972h-)

Spom972h-STK39


"A STE20/SPS1-related proline-alanine-rich protein kinase that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:DNx]


organism-gene



PR:Q9UEW8

STE20/SPS1-related proline-alanine-rich protein kinase (human)

hSTK39


"A STE20/SPS1-related proline-alanine-rich protein kinase that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UEW8]


organism-sequence



PR:Q9UEW8-1

STE20/SPS1-related proline-alanine-rich protein kinase isoform h1 (human)

hSTK39/iso:h1


"A STE20/SPS1-related proline-alanine-rich protein kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UEW8-1." [PRO:DNx, UniProtKB:Q9UEW8]


organism-sequence



PR:Q9UEW8-2

STE20/SPS1-related proline-alanine-rich protein kinase isoform h2 (human)

hSTK39/iso:h2


"A STE20/SPS1-related proline-alanine-rich protein kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UEW8-2." [PRO:DNx, UniProtKB:Q9UEW8]


organism-modification



PR:000077909

STE20/SPS1-related proline-alanine-rich protein kinase methylated 1 (human)

hSTK39/Me:1


"A STE20/SPS1-related proline-alanine-rich protein kinase (human) that has been methylated on the residue at the position equivalent to Cys-116 of the amino acid sequence represented by UniProtKB:Q9UEW8-1. Example: UniProtKB:Q9UEW8-1, Cys-116, MOD:00660." [IEDB_epitope:1051086, PRO:DNx]


organism-gene



PR:Q9Z1W9

STE20/SPS1-related proline-alanine-rich protein kinase (mouse)

mSTK39


"A STE20/SPS1-related proline-alanine-rich protein kinase that is encoded in the genome of mouse." [OMA:Q9Z1W9, PRO:DNx]


organism-sequence



PR:000044370

STE20/SPS1-related proline-alanine-rich protein kinase isoform 3 (mouse)

mSTK39/iso:3


"A STE20/SPS1-related proline-alanine-rich protein kinase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z1W9, 115-556." [PMID:21907141, PMID:24133122, PRO:HJD]

Yes

organism-sequence



PR:G1JLS7

STE20/SPS1-related proline-alanine-rich protein kinase isoform 2 (mouse)

mSTK39/iso:2


"A STE20/SPS1-related proline-alanine-rich protein kinase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:G1JLS7." [PMID:21907141, PMID:24133122, PRO:HJD]

Yes

organism-sequence



PR:Q9Z1W9-1

STE20/SPS1-related proline-alanine-rich protein kinase isoform 1 (mouse)

mSTK39/iso:1


"A STE20/SPS1-related proline-alanine-rich protein kinase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z1W9-1." [PMID:10980603, PRO:HJD]

Yes

modification



PR:000021589

STE20/SPS1-related proline-alanine-rich protein kinase, initiator methionine removed form

STK39/InitMet-


"A STE20/SPS1-related proline-alanine-rich protein kinase that has had the initiator methionine removed." [PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000044370 mSTK39/iso:3 enablesGO:0005515 protein binding with PR:P55014-4 MGI_ref:5538439; PMID:24133122
PR:G1JLS7 mSTK39/iso:2 acts_upstream_of_or_withinGO:0001933 negative regulation of protein phosphorylation MGI_ref:5292405; PMID:21907141
GO:1901380 negative regulation of potassium ion transmembrane transport MGI_ref:5538439; PMID:24133122
enablesGO:0005515 protein binding with PR:P55014-4 MGI_ref:5538439; PMID:24133122
PR:Q9Z1W9-1 mSTK39/iso:1 enablesGO:0004672 protein kinase activity MGI_ref:5292405; PMID:21907141
GO:0005515 protein binding MGI_ref:5538439; PMID:24133122