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Protein Ontology report - alpha-synuclein
PR:000015322 - http://purl.obolibrary.org/obo/PR_000015322
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000015322   
  PRO namealpha-synuclein 
  Synonyms
PRO-Short-label: EXACT:SNCA
Gene-based: RELATED:NACP | PARK1 | Syn
Other: EXACT:non-A beta component of AD amyloid | non-A4 component of amyloid precursor
  Definition"A protein that is a translation product of the human SNCA gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 9                                        
         Modification0                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000015322

alpha-synuclein

SNCA


"A protein that is a translation product of the human SNCA gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O55042

alpha-synuclein (mouse)

mSNCA


"An alpha-synuclein that is encoded in the genome of mouse." [OMA:O55042, PRO:DNx]


organism-sequence



PR:O55042-1

alpha-synuclein isoform 1 (mouse)

mSNCA/iso:1


"An alpha-synuclein isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:O55042-2

alpha-synuclein isoform m2 (mouse)

mSNCA/iso:m2


"An alpha-synuclein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O55042-2." [PRO:DNx, UniProtKB:O55042]


organism-modification



PR:000046117

alpha-synuclein phosphorylated 1 (mouse)

mSNCA/Phos:1


"An alpha-synuclein (mouse) that has been phosphorylated on the residue at the position equivalent to Ser-129 of the amino acid sequence represented by UniProtKB:O55042-1. Example: UniProtKB:O55042-1, Ser-129, MOD:00046." [iPTMnet:O55042, PMID:15304353]


organism-gene



PR:P37377

alpha-synuclein (rat)

rSNCA


"An alpha-synuclein that is encoded in the genome of rat." [OMA:P37377, PRO:DNx]


organism-sequence



PR:P37377-1

alpha-synuclein isoform Syn1 (rat)

rSNCA/iso:Syn1


"An alpha-synuclein isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P37377-2

alpha-synuclein isoform rSyn2 (rat)

rSNCA/iso:rSyn2


"An alpha-synuclein (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P37377-2." [PRO:DNx, UniProtKB:P37377]


organism-sequence



PR:P37377-3

alpha-synuclein isoform rSyn3 (rat)

rSNCA/iso:rSyn3


"An alpha-synuclein (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P37377-3." [PRO:DNx, UniProtKB:P37377]


organism-gene



PR:P37840

alpha-synuclein (human)

hSNCA


"An alpha-synuclein that is encoded in the genome of human." [PRO:DNx, UniProtKB:P37840]


organism-sequence



PR:000061032

alpha-synuclein sequence variant A30P (human)

hSNCA/var:A30P


"An alpha-synuclein (human) that has a Pro residue at the position equivalent to Ala-30 of the amino acid sequence represented by UniProtKB:P37840-1. Example: UniProtKB:P37840-1, Ala-30, CHEBI:50342." [PRO:DNx, Reactome:R-HSA-5658569]


organism-sequence



PR:P37840-1

alpha-synuclein isoform 1 (human)

hSNCA/iso:1


"An alpha-synuclein isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P37840-2

alpha-synuclein isoform h2-4 (human)

hSNCA/iso:h2-4


"An alpha-synuclein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P37840-2." [PRO:DNx, UniProtKB:P37840]


organism-sequence



PR:P37840-3

alpha-synuclein isoform h2-5 (human)

hSNCA/iso:h2-5


"An alpha-synuclein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P37840-3." [PRO:DNx, UniProtKB:P37840]


organism-modification



PR:000045769

alpha-synuclein phosphorylated 1 (human)

hSNCA/Phos:1


"An alpha-synuclein (human) that has been phosphorylated on the residue at the position equivalent to Tyr-125 of the amino acid sequence represented by UniProtKB:P37840-1. Example: UniProtKB:P37840-1, Tyr-125, MOD:00048." [iPTMnet:P37840, PMID:12893833]


organism-modification



PR:000049305

alpha-synuclein ubiquitinated form (human)

hSNCA/UbiqLys+


"An alpha-synuclein (human) that includes at least one ubiquitinated lysine. UniProtKB:P37840, MOD:01148." [PRO:DNx, Reactome:R-HSA-5660754]


organism-modification



PR:000063534

alpha-synuclein phosphorylated 2 (human)

hSNCA/Phos:2


"An alpha-synuclein (human) that has been phosphorylated on the residue at the position equivalent to Ser-129 of the amino acid sequence represented by UniProtKB:P37840-1. Example: UniProtKB:P37840-1, Ser-129, MOD:00046." [PRO:DNx, Reactome:R-HSA-9836432]


organism-modification



PR:000080658

alpha-synuclein phosphorylated 3 (human)

hSNCA/Phos:3


"An alpha-synuclein (human) that has been phosphorylated on the residue at the position equivalent to Tyr-39 of the amino acid sequence represented by UniProtKB:P37840-1. Example: UniProtKB:P37840-1, Tyr-39, MOD:00048." [IEDB_epitope:668728, PRO:DNx]


sequence



PR:000039381

alpha-synuclein isoform 1

SNCA/iso:1


"An alpha-synuclein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P37840-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:O55042-1

alpha-synuclein isoform 1 (mouse)

mSNCA/iso:1


"An alpha-synuclein isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:P37377-1

alpha-synuclein isoform Syn1 (rat)

rSNCA/iso:Syn1


"An alpha-synuclein isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P37840-1

alpha-synuclein isoform 1 (human)

hSNCA/iso:1


"An alpha-synuclein isoform 1 that is encoded in the genome of human." [PRO:DNx]