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Protein Ontology report - sodium/hydrogen exchanger 8
PR:000015220 - http://purl.obolibrary.org/obo/PR_000015220
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000015220   
  PRO namesodium/hydrogen exchanger 8 
  Synonyms
PRO-Short-label: EXACT:SLC9A8
Gene-based: RELATED:KIAA0939 | NHE8
Other: EXACT:Na(+)/H(+) exchanger 8 | NHE-8 | solute carrier family 9 member 8
  Definition"A protein that is a translation product of the human SLC9A8 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 7                                        
         Sequence0                                                  Organism-Sequence 5                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:955
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000015220 sodium/hydrogen exchanger 8
SLC9A8

organism-gene


PR:P32703 uncharacterized Na(+)/H(+) exchanger YjcE (Escherichia coli K-12)
Ec-SLC9A8

organism-gene


PR:Q4L208 sodium/hydrogen exchanger 8 (rat)
rSLC9A8

organism-gene


PR:Q552S0 sodium/hydrogen exchanger 1 (Dictyostelium discoideum)
Dicty-SLC9A8

organism-gene


PR:Q5ZJ75 sodium/hydrogen exchanger 8 (chicken)
chick-SLC9A8

organism-gene


PR:Q84WG1 sodium/hydrogen exchanger 3 (Arabidopsis thaliana)
At-SLC9A8

organism-gene


PR:Q8R4D1 sodium/hydrogen exchanger 8 (mouse)
mSLC9A8

organism-sequence


PR:Q8R4D1-1 sodium/hydrogen exchanger 8 isoform 1 (mouse)
mSLC9A8/iso:1
Yes
organism-sequence


PR:Q8R4D1-2 sodium/hydrogen exchanger 8 isoform 2 (mouse)
mSLC9A8/iso:2

organism-sequence


PR:Q8R4D1-4 sodium/hydrogen exchanger 8 isoform 3 (mouse)
mSLC9A8/iso:3

organism-gene


PR:Q9Y2E8 sodium/hydrogen exchanger 8 (human)
hSLC9A8

organism-sequence


PR:Q9Y2E8-1 sodium/hydrogen exchanger 8 isoform h1 (human)
hSLC9A8/iso:h1

organism-sequence


PR:Q9Y2E8-2 sodium/hydrogen exchanger 8 isoform h2 (human)
hSLC9A8/iso:h2

organism-modification


PR:000079798 sodium/hydrogen exchanger 8 deaminated 1 (human)
hSLC9A8/Deam:1

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0006813 potassium ion transportPR:Q8R4D1-1 mSLC9A8/iso:1 MGI_ref:3529663; PMID:15522866
GO:0006814 sodium ion transportPR:Q8R4D1-1 mSLC9A8/iso:1 MGI_ref:3529663; PMID:15522866
GO:0051453 regulation of intracellular pHPR:Q8R4D1-1 mSLC9A8/iso:1 MGI_ref:3529663; PMID:15522866

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0015385 sodium:proton antiporter activityPR:Q8R4D1-1 mSLC9A8/iso:1 MGI_ref:3529663; PMID:15522866
GO:0015386 potassium:proton antiporter activityPR:Q8R4D1-1 mSLC9A8/iso:1 MGI_ref:3529663; PMID:15522866

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005794 Golgi apparatusPR:Q8R4D1-1 mSLC9A8/iso:1 MGI_ref:3529663; PMID:15522866