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Protein Ontology report - sodium/hydrogen exchanger 8
PR:000015220 - http://purl.obolibrary.org/obo/PR_000015220
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000015220   
  PRO namesodium/hydrogen exchanger 8 
  Synonyms
PRO-Short-label: EXACT:SLC9A8
Gene-based: RELATED:KIAA0939 | NHE8
Other: EXACT:Na(+)/H(+) exchanger 8 | NHE-8 | solute carrier family 9 member 8
  Definition"A protein that is a translation product of the human SLC9A8 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 7                                        
         Sequence0                                                  Organism-Sequence 5                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:955
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000015220

sodium/hydrogen exchanger 8

SLC9A8


"A protein that is a translation product of the human SLC9A8 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P32703

uncharacterized Na(+)/H(+) exchanger YjcE (Escherichia coli K-12)

Ec-SLC9A8


"A sodium/hydrogen exchanger 8 that is encoded in the genome of Escherichia coli K-12." [PRO:DNx]


organism-gene



PR:Q4L208

sodium/hydrogen exchanger 8 (rat)

rSLC9A8


"A sodium/hydrogen exchanger 8 that is encoded in the genome of rat." [OMA:Q4L208, PRO:DNx]


organism-gene



PR:Q552S0

sodium/hydrogen exchanger 1 (Dictyostelium discoideum)

Dicty-SLC9A8


"A sodium/hydrogen exchanger 8 that is encoded in the genome of Dictyostelium discoideum." [PRO:DNx]


organism-gene



PR:Q5ZJ75

sodium/hydrogen exchanger 8 (chicken)

chick-SLC9A8


"A sodium/hydrogen exchanger 8 that is encoded in the genome of chicken." [PRO:DNx]


organism-gene



PR:Q84WG1

sodium/hydrogen exchanger 3 (Arabidopsis thaliana)

At-SLC9A8


"A sodium/hydrogen exchanger 8 that is encoded in the genome of Arabidopsis thaliana." [PRO:DNx]


organism-gene



PR:Q8R4D1

sodium/hydrogen exchanger 8 (mouse)

mSLC9A8


"A sodium/hydrogen exchanger 8 that is encoded in the genome of mouse." [OMA:Q8R4D1, PRO:DNx]


organism-sequence



PR:Q8R4D1-1

sodium/hydrogen exchanger 8 isoform 1 (mouse)

mSLC9A8/iso:1


"A sodium/hydrogen exchanger 8 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8R4D1-1." [PRO:DNx, UniProtKB:Q8R4D1]

Yes

organism-sequence



PR:Q8R4D1-2

sodium/hydrogen exchanger 8 isoform 2 (mouse)

mSLC9A8/iso:2


"A sodium/hydrogen exchanger 8 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8R4D1-2." [PRO:DNx, UniProtKB:Q8R4D1]


organism-sequence



PR:Q8R4D1-4

sodium/hydrogen exchanger 8 isoform 3 (mouse)

mSLC9A8/iso:3


"A sodium/hydrogen exchanger 8 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8R4D1-4." [PRO:DNx, UniProtKB:Q8R4D1]


organism-gene



PR:Q9Y2E8

sodium/hydrogen exchanger 8 (human)

hSLC9A8


"A sodium/hydrogen exchanger 8 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9Y2E8]


organism-sequence



PR:Q9Y2E8-1

sodium/hydrogen exchanger 8 isoform h1 (human)

hSLC9A8/iso:h1


"A sodium/hydrogen exchanger 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y2E8-1." [PRO:DNx, UniProtKB:Q9Y2E8]


organism-sequence



PR:Q9Y2E8-2

sodium/hydrogen exchanger 8 isoform h2 (human)

hSLC9A8/iso:h2


"A sodium/hydrogen exchanger 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y2E8-2." [PRO:DNx, UniProtKB:Q9Y2E8]


organism-modification



PR:000079798

sodium/hydrogen exchanger 8 deaminated 1 (human)

hSLC9A8/Deam:1


"A sodium/hydrogen exchanger 8 (human) that has been deaminated on the residue at the position equivalent to Asn-396 of the amino acid sequence represented by UniProtKB:Q9Y2E8-1. Example: UniProtKB:Q9Y2E8-1, Asn-396, MOD:00684." [IEDB_epitope:1332900, PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q8R4D1-1 mSLC9A8/iso:1 acts_upstream_of_or_withinGO:0006813 potassium ion transport MGI_ref:3529663; PMID:15522866
GO:0006814 sodium ion transport MGI_ref:3529663; PMID:15522866
GO:0051453 regulation of intracellular pH MGI_ref:3529663; PMID:15522866
enablesGO:0015385 sodium:proton antiporter activity MGI_ref:3529663; PMID:15522866
GO:0015386 potassium:proton antiporter activity MGI_ref:3529663; PMID:15522866
located_inGO:0005794 Golgi apparatus MGI_ref:3529663; PMID:15522866