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Protein Ontology report - zinc transporter ZIP4
PR:000015131 - http://purl.obolibrary.org/obo/PR_000015131
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000015131   
  PRO namezinc transporter ZIP4 
  Synonyms
PRO-Short-label: EXACT:SLC39A4
Gene-based: RELATED:ZIP4
Other: EXACT:activated in W/Wv mouse stomach 2 | AWMS2 | solute carrier family 39 member 4 | ZIP-4 | Zrt- and Irt-like protein 4
  Definition"A protein that is a translation product of the human SLC39A4 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1183
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000015131

zinc transporter ZIP4

SLC39A4


"A protein that is a translation product of the human SLC39A4 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:A0JPN2

zinc transporter ZIP4 (rat)

rSLC39A4


"A zinc transporter ZIP4 that is encoded in the genome of rat." [OMA:A0JPN2, PRO:DNx]


organism-gene



PR:Q6P5W5

zinc transporter ZIP4 (human)

hSLC39A4


"A zinc transporter ZIP4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q6P5W5]


organism-sequence



PR:Q6P5W5-1

zinc transporter ZIP4 isoform h1 (human)

hSLC39A4/iso:h1


"A zinc transporter ZIP4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6P5W5-1." [PRO:DNx, UniProtKB:Q6P5W5]


organism-sequence



PR:Q6P5W5-2

zinc transporter ZIP4 isoform h2 (human)

hSLC39A4/iso:h2


"A zinc transporter ZIP4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6P5W5-2." [PRO:DNx, UniProtKB:Q6P5W5]


organism-modification



PR:000049269

zinc transporter ZIP4, signal peptide removed form (human)

hSLC39A4/SigPep-


"A zinc transporter ZIP4 (human) that has had the signal peptide removed. UniProtKB:Q6P5W5, 23-647." [PRO:DNx, Reactome:R-HSA-442399]


organism-modification



PR:000060495

zinc transporter ZIP4 sequence variant G526R, signal peptide removed form (human)

hSLC39A4/var:G526R/SigPep-


"A zinc transporter ZIP4 (human) that has an Arg residue at the position equivalent to Gly-526 of the amino acid sequence represented by UniProtKB:Q6P5W5-1 and that has had the signal peptide removed. Example: UniProtKB:Q6P5W5-1, 23-647, Gly-526, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-5654120]


organism-modification



PR:000062898

zinc transporter ZIP4 sequence variant G330D, signal peptide removed form (human)

hSLC39A4/var:G330D/SigPep-


"A zinc transporter ZIP4 (human) that has an Asp residue at the position equivalent to Gly-330 of the amino acid sequence represented by UniProtKB:Q6P5W5-1 and that has had the signal peptide removed. Example: UniProtKB:Q6P5W5-1, 23-647, Gly-330, CHEBI:29958." [PRO:DNx, Reactome:R-HSA-5654117]


organism-modification



PR:000063458

zinc transporter ZIP4 sequence variant P200L, signal peptide removed form (human)

hSLC39A4/var:P200L/SigPep-


"A zinc transporter ZIP4 (human) that has a Leu residue at the position equivalent to Pro-200 of the amino acid sequence represented by UniProtKB:Q6P5W5-1 and that has had the signal peptide removed. Example: UniProtKB:Q6P5W5-1, 23-647, Pro-200, CHEBI:30006." [PRO:DNx, Reactome:R-HSA-5654131]


organism-modification



PR:000063712

zinc transporter ZIP4 sequence variant G512W, signal peptide removed form (human)

hSLC39A4/var:G512W/SigPep-


"A zinc transporter ZIP4 (human) that has a Trp residue at the position equivalent to Gly-512 of the amino acid sequence represented by UniProtKB:Q6P5W5-1 and that has had the signal peptide removed. Example: UniProtKB:Q6P5W5-1, 23-647, Gly-512, CHEBI:29954." [PRO:DNx, Reactome:R-HSA-5654106]


organism-modification



PR:000064051

zinc transporter ZIP4 sequence variant R95C, signal peptide removed form (human)

hSLC39A4/var:R95C/SigPep-


"A zinc transporter ZIP4 (human) that has a Cys residue at the position equivalent to Arg-95 of the amino acid sequence represented by UniProtKB:Q6P5W5-1 and that has had the signal peptide removed. Example: UniProtKB:Q6P5W5-1, 23-647, Arg-95, CHEBI:29950." [PRO:DNx, Reactome:R-HSA-5654137]


organism-gene



PR:Q78IQ7

zinc transporter ZIP4 (mouse)

mSLC39A4


"A zinc transporter ZIP4 that is encoded in the genome of mouse." [OMA:Q78IQ7, PRO:DNx]


organism-sequence



PR:Q78IQ7-1

zinc transporter ZIP4 isoform 1 (mouse)

mSLC39A4/iso:1


"A zinc transporter ZIP4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q78IQ7-1." [PRO:DNx, UniProtKB:Q78IQ7]

Yes

organism-sequence



PR:Q78IQ7-2

zinc transporter ZIP4 isoform m2 (mouse)

mSLC39A4/iso:m2


"A zinc transporter ZIP4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q78IQ7-2." [PRO:DNx, UniProtKB:Q78IQ7]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q78IQ7-1 mSLC39A4/iso:1 acts_upstream_of_or_withinGO:0006882 intracellular zinc ion homeostasis MGI_ref:3028750; PMID:14612438
enablesGO:0005385 zinc ion transmembrane transporter activity MGI_ref:3028750; PMID:14612438
GO:0005385 zinc ion transmembrane transporter activity MGI_ref:3028750; PMID:14612438
located_inGO:0005768 endosome MGI_ref:3028750; PMID:14612438
GO:0005886 plasma membrane MGI_ref:3028750; PMID:14612438
GO:0016324 apical plasma membrane MGI_ref:2684332; PMID:12801924
GO:0031410 cytoplasmic vesicle MGI_ref:3028750; PMID:14612438