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Protein Ontology report - NAD-dependent protein deacetylase sirtuin-2
PR:000014889 - http://purl.obolibrary.org/obo/PR_000014889
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000014889   
  PRO nameNAD-dependent protein deacetylase sirtuin-2 
  Synonyms
PRO-Short-label: EXACT:SIRT2
Gene-based: RELATED:SIR2L | SIR2L2
Other: EXACT:NAD-dependent deacetylase sirtuin-2 | NAD-dependent protein defatty-acylase sirtuin-2 | regulatory protein SIR2 homolog 2 | SIR2-like protein 2
  Definition"A protein that is a translation product of the human SIRT2 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 8                                        
         Sequence1                                                  Organism-Sequence 9                                        
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2708
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000014889
NAD-dependent protein deacetylase sirtuin-2
SIRT2
"A protein that is a translation product of the human SIRT2 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P53686
NAD-dependent protein deacetylase HST2 (yeast)
ySIRT2
"An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of yeast." [PRO:DNx]

organism-gene


PR:Q54QE6
NAD-dependent deacetylase sir2A (Dictyostelium discoideum)
Dicty-SIRT2
"An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of Dictyostelium discoideum." [PRO:DNx]

organism-gene


PR:Q5RJQ4
NAD-dependent protein deacetylase sirtuin-2 (rat)
rSIRT2
"An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of rat." [OMA:Q5RJQ4, PRO:DNx]

organism-gene


PR:Q7ZVK3
NAD-dependent protein deacetylase sirtuin-2 (zebrafish)
z-SIRT2
"An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of zebrafish." [PRO:DNx]

organism-gene


PR:Q8IXJ6
NAD-dependent protein deacetylase sirtuin-2 (human)
hSIRT2
"An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8IXJ6]

organism-sequence


PR:Q8IXJ6-1
NAD-dependent protein deacetylase sirtuin-2 isoform 1 (human)
hSIRT2/iso:1
"An NAD-dependent protein deacetylase sirtuin-2 isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:Q8IXJ6-2
NAD-dependent protein deacetylase sirtuin-2 isoform h2 (human)
hSIRT2/iso:h2
"An NAD-dependent protein deacetylase sirtuin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IXJ6-2." [PRO:DNx, UniProtKB:Q8IXJ6]

organism-sequence


PR:Q8IXJ6-3
NAD-dependent protein deacetylase sirtuin-2 isoform h3 (human)
hSIRT2/iso:h3
"An NAD-dependent protein deacetylase sirtuin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IXJ6-3." [PRO:DNx, UniProtKB:Q8IXJ6]

organism-sequence


PR:Q8IXJ6-4
NAD-dependent protein deacetylase sirtuin-2 isoform h4 (human)
hSIRT2/iso:h4
"An NAD-dependent protein deacetylase sirtuin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IXJ6-4." [PRO:DNx, UniProtKB:Q8IXJ6]

organism-sequence


PR:Q8IXJ6-5
NAD-dependent protein deacetylase sirtuin-2 isoform h5 (human)
hSIRT2/iso:h5
"An NAD-dependent protein deacetylase sirtuin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IXJ6-5." [PRO:DNx, UniProtKB:Q8IXJ6]

organism-modification


PR:000064139
NAD-dependent protein deacetylase sirtuin-2, initiator methionine removed form (human)
hSIRT2/InitMet-
"An NAD-dependent protein deacetylase sirtuin-2 (human) that has had the initiator methionine removed. Example: UniProtKB:Q8IXJ6-1, 2-389." [PRO:DNx, Reactome:R-HSA-2161118]

organism-modification


PR:000070095
NAD-dependent protein deacetylase sirtuin-2 methylated 1 (human)
hSIRT2/Me:1
"An NAD-dependent protein deacetylase sirtuin-2 (human) that has been methylated on the residue at the position equivalent to Cys-246 of the amino acid sequence represented by UniProtKB:Q8IXJ6-1. Example: UniProtKB:Q8IXJ6-1, Cys-246, MOD:00660." [IEDB_epitope:1030493, PRO:DNx]

organism-gene


PR:Q8VDQ8
NAD-dependent protein deacetylase sirtuin-2 (mouse)
mSIRT2
"An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of mouse." [OMA:Q8VDQ8, PRO:DNx]

organism-sequence


PR:Q8VDQ8-1
NAD-dependent protein deacetylase sirtuin-2 isoform 1 (mouse)
mSIRT2/iso:1
"An NAD-dependent protein deacetylase sirtuin-2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:Q8VDQ8-2
NAD-dependent protein deacetylase sirtuin-2 isoform m2 (mouse)
mSIRT2/iso:m2
"An NAD-dependent protein deacetylase sirtuin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8VDQ8-2." [PRO:DNx, UniProtKB:Q8VDQ8]

organism-sequence


PR:Q8VDQ8-3
NAD-dependent protein deacetylase sirtuin-2 isoform m3 (mouse)
mSIRT2/iso:m3
"An NAD-dependent protein deacetylase sirtuin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8VDQ8-3." [PRO:DNx, UniProtKB:Q8VDQ8]

organism-sequence


PR:Q8VDQ8-4
NAD-dependent protein deacetylase sirtuin-2 isoform m4 (mouse)
mSIRT2/iso:m4
"An NAD-dependent protein deacetylase sirtuin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8VDQ8-4." [PRO:DNx, UniProtKB:Q8VDQ8]

organism-gene


PR:Q9I7I7
NAD-dependent protein deacetylase Sirt2 (fruit fly)
fly-SIRT2
"An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of fruit fly." [OMA:Q9I7I7, PRO:DNx]

organism-gene


PR:Q9USN7
NAD-dependent protein deacetylase hst2 (Schizosaccharomyces pombe 972h-)
Spom972h-SIRT2
"An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:DNx]

sequence


PR:000041728
NAD-dependent protein deacetylase sirtuin-2 isoform 1
SIRT2/iso:1
"An NAD-dependent protein deacetylase sirtuin-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IXJ6-1 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:Q8IXJ6-1
NAD-dependent protein deacetylase sirtuin-2 isoform 1 (human)
hSIRT2/iso:1
"An NAD-dependent protein deacetylase sirtuin-2 isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:Q8VDQ8-1
NAD-dependent protein deacetylase sirtuin-2 isoform 1 (mouse)
mSIRT2/iso:1
"An NAD-dependent protein deacetylase sirtuin-2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

modification


PR:000021481
NAD-dependent protein deacetylase sirtuin-2, initiator methionine removed form
SIRT2/InitMet-
"An NAD-dependent protein deacetylase sirtuin-2 that has had the initiator methionine removed." [PRO:DNx]

organism-modification


PR:000064139
NAD-dependent protein deacetylase sirtuin-2, initiator methionine removed form (human)
hSIRT2/InitMet-
"An NAD-dependent protein deacetylase sirtuin-2 (human) that has had the initiator methionine removed. Example: UniProtKB:Q8IXJ6-1, 2-389." [PRO:DNx, Reactome:R-HSA-2161118]