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Protein Ontology report - sentrin-specific protease 2
PR:000014636 - http://purl.obolibrary.org/obo/PR_000014636
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000014636   
  PRO namesentrin-specific protease 2 
  Synonyms
PRO-Short-label: EXACT:SENP2
Gene-based: RELATED:KIAA1331 | Smt3ip2 | Supr1
Other: EXACT:Axam2 | sentrin/SUMO-specific protease SENP2 | SMT3-specific isopeptidase 2 | SUMO-1 protease 1 | SUMO-1/Smt3-specific isopeptidase 2 | SuPr-1
  Definition"A protein that is a translation product of the human SENP2 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 5                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000014636 sentrin-specific protease 2
SENP2

organism-gene


PR:Q91ZX6 sentrin-specific protease 2 (mouse)
mSENP2

organism-sequence


PR:Q91ZX6-1 sentrin-specific protease 2 isoform 1 (mouse)
mSENP2/iso:1
Yes
organism-sequence


PR:Q91ZX6-2 sentrin-specific protease 2 isoform 2 (mouse)
mSENP2/iso:2
Yes
organism-sequence


PR:Q91ZX6-3 sentrin-specific protease 2 isoform 3 (mouse)
mSENP2/iso:3
Yes
organism-gene


PR:Q9EQE1 sentrin-specific protease 2 (rat)
rSENP2

organism-gene


PR:Q9HC62 sentrin-specific protease 2 (human)
hSENP2

organism-sequence


PR:Q9HC62-1 sentrin-specific protease 2 isoform h1 (human)
hSENP2/iso:h1

organism-sequence


PR:Q9HC62-2 sentrin-specific protease 2 isoform h2 (human)
hSENP2/iso:h2

organism-modification


PR:000080694 sentrin-specific protease 2 methylated 1 (human)
hSENP2/Me:1

organism-modification


PR:000085422 sentrin-specific protease 2 cysteinylated 1 (human)
hSENP2/Cyst:1

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0016926 protein desumoylationPR:Q91ZX6-1 mSENP2/iso:1 MGI_ref:5433829; PMID:21183956
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediatorPR:Q91ZX6-1 mSENP2/iso:1 MGI_ref:5433829; PMID:21183956
GO:1901797 negative regulation of signal transduction by p53 class mediatorPR:Q91ZX6-1 mSENP2/iso:1 MGI_ref:5433829; PMID:21183956

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0016929 deSUMOylase activityPR:Q91ZX6-1 mSENP2/iso:1 MGI_ref:5433829; PMID:21183956

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005634 nucleusPR:Q91ZX6-1 mSENP2/iso:1 MGI_ref:5433829; PMID:21183956
GO:0005737 cytoplasmPR:Q91ZX6-3 mSENP2/iso:3 MGI_ref:5433829; PMID:21183956
GO:0031410 cytoplasmic vesiclePR:Q91ZX6-2 mSENP2/iso:2 MGI_ref:5433829; PMID:21183956