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Protein Ontology report - NAD(+) hydrolase SARM1
PR:000014458 - http://purl.obolibrary.org/obo/PR_000014458
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000014458   
  PRO nameNAD(+) hydrolase SARM1 
  Synonyms
PRO-Short-label: EXACT:SARM1
Gene-based: RELATED:KIAA0524 | SAMD2 | SARM
Other: EXACT:MyD88-5 | NADase SARM1 | NADP(+) hydrolase SARM1 | SAM domain-containing protein 2 | sterile alpha and Armadillo repeat protein | sterile alpha and TIR motif-containing protein 1 | sterile alpha motif domain-containing protein 2 | Tir-1 homolog
  Definition"A protein that is a translation product of the human SARM1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 7                                        
         Sequence1                                                  Organism-Sequence 13                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000014458
NAD(+) hydrolase SARM1
SARM1
"A protein that is a translation product of the human SARM1 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:D3ZUM2
NAD(+) hydrolase SARM1 (rat)
rSARM1
"An NAD(+) hydrolase SARM1 that is encoded in the genome of rat." [OMA:D3ZUM2, PRO:DNx]

organism-gene


PR:E1C797
uncharacterized protein, SARM1 translation product (chicken)
chick-SARM1
"An NAD(+) hydrolase SARM1 that is encoded in the genome of chicken." [OMA:E1C797, PRO:DNx]

organism-gene


PR:F1QWA8
NAD(+) hydrolase SARM1 (zebrafish)
z-SARM1
"An NAD(+) hydrolase SARM1 that is encoded in the genome of zebrafish." [OMA:F1QWA8, PRO:DNx]

organism-gene


PR:Q6IDD9
NAD(+) hydrolase sarm1 (fruit fly)
fly-SARM1
"An NAD(+) hydrolase SARM1 that is encoded in the genome of fruit fly." [PANTHER:PTHR22998:SF0, PRO:DNx]

organism-sequence


PR:Q6IDD9-1
NAD(+) hydrolase sarm1 isoform C (fruit fly)
fly-SARM1/iso:C
"An NAD(+) hydrolase sarm1 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6IDD9-1." [PRO:DNx, UniProtKB:Q6IDD9]

organism-sequence


PR:Q6IDD9-2
NAD(+) hydrolase sarm1 isoform B (fruit fly)
fly-SARM1/iso:B
"An NAD(+) hydrolase sarm1 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6IDD9-2." [PRO:DNx, UniProtKB:Q6IDD9]

organism-gene


PR:Q6PDS3
NAD(+) hydrolase SARM1 (mouse)
mSARM1
"An NAD(+) hydrolase SARM1 that is encoded in the genome of mouse." [OMA:Q6PDS3, PRO:DNx]

organism-sequence


PR:Q6PDS3-1
NAD(+) hydrolase SARM1 isoform 1 (mouse)
mSARM1/iso:1
"An NAD(+) hydrolase SARM1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA, UniProtKB:Q6PDS3]

organism-sequence


PR:Q6PDS3-2
NAD(+) hydrolase SARM1 isoform m2 (mouse)
mSARM1/iso:m2
"An NAD(+) hydrolase SARM1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6PDS3-2." [PRO:DNx, UniProtKB:Q6PDS3]

organism-sequence


PR:Q6PDS3-3
NAD(+) hydrolase SARM1 isoform m3 (mouse)
mSARM1/iso:m3
"An NAD(+) hydrolase SARM1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6PDS3-3." [PRO:DNx, UniProtKB:Q6PDS3]

organism-sequence


PR:Q6PDS3-4
NAD(+) hydrolase SARM1 isoform m4 (mouse)
mSARM1/iso:m4
"An NAD(+) hydrolase SARM1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6PDS3-4." [PRO:DNx, UniProtKB:Q6PDS3]

organism-gene


PR:Q6SZW1
NAD(+) hydrolase SARM1 (human)
hSARM1
"An NAD(+) hydrolase SARM1 that is encoded in the genome of human." [PRO:CNA]

organism-sequence


PR:Q6SZW1-1
NAD(+) hydrolase SARM1 isoform 1 (human)
hSARM1/iso:1
"An NAD(+) hydrolase SARM1 isoform 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q6SZW1]

Yes
organism-sequence


PR:Q6SZW1-2
NAD(+) hydrolase SARM1 isoform h2 (human)
hSARM1/iso:h2
"An NAD(+) hydrolase SARM1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6SZW1-2." [PRO:DNx, UniProtKB:Q6SZW1]

organism-modification


PR:000064956
NAD(+) hydrolase SARM1 citrullinated 1 (human)
hSARM1/Cit:1
"An NAD(+) hydrolase SARM1 (human) that has been citrullinated on the residue at the position equivalent to Arg-403 of the amino acid sequence represented by UniProtKB:Q6SZW1-1. Example: UniProtKB:Q6SZW1-1, Arg-403, MOD:00219." [IEDB_epitope:912437, PRO:DNx]

organism-modification


PR:000083011
NAD(+) hydrolase SARM1 methylated 1 (human)
hSARM1/Me:1
"An NAD(+) hydrolase SARM1 (human) that has been methylated on the residue at the position equivalent to Cys-271 of the amino acid sequence represented by UniProtKB:Q6SZW1-1. Example: UniProtKB:Q6SZW1-1, Cys-271, MOD:00660." [IEDB_epitope:1017252, PRO:DNx]

organism-gene


PR:Q86DA5
NAD(+) hydrolase tir-1 (worm)
SARM1 (worm)
"An NAD(+) hydrolase SARM1 that is encoded in the genome of worm." [OMA:Q86DA5, PRO:DNx]

organism-sequence


PR:Q86DA5-1
NAD(+) hydrolase tir-1 isoform c (worm)
SARM1/iso:c (worm)
"An NAD(+) hydrolase tir-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86DA5-1." [PRO:DNx, UniProtKB:Q86DA5]

organism-sequence


PR:Q86DA5-2
NAD(+) hydrolase tir-1 isoform a (worm)
SARM1/iso:a (worm)
"An NAD(+) hydrolase tir-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86DA5-2." [PRO:DNx, UniProtKB:Q86DA5]

organism-sequence


PR:Q86DA5-3
NAD(+) hydrolase tir-1 isoform b (worm)
SARM1/iso:b (worm)
"An NAD(+) hydrolase tir-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86DA5-3." [PRO:DNx, UniProtKB:Q86DA5]

organism-sequence


PR:Q86DA5-4
NAD(+) hydrolase tir-1 isoform d (worm)
SARM1/iso:d (worm)
"An NAD(+) hydrolase tir-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86DA5-4." [PRO:DNx, UniProtKB:Q86DA5]

organism-sequence


PR:Q86DA5-5
NAD(+) hydrolase tir-1 isoform e (worm)
SARM1/iso:e (worm)
"An NAD(+) hydrolase tir-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86DA5-5." [PRO:DNx, UniProtKB:Q86DA5]

sequence


PR:000037484
NAD(+) hydrolase SARM1 isoform 1
SARM1/iso:1
"An NAD(+) hydrolase SARM1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6SZW1-1 or a 1:1 ortholog thereof." [PRO:CNA, UniProtKB:Q6PDS3, UniProtKB:Q6SZW1]

organism-sequence


PR:Q6PDS3-1
NAD(+) hydrolase SARM1 isoform 1 (mouse)
mSARM1/iso:1
"An NAD(+) hydrolase SARM1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA, UniProtKB:Q6PDS3]

organism-sequence


PR:Q6SZW1-1
NAD(+) hydrolase SARM1 isoform 1 (human)
hSARM1/iso:1
"An NAD(+) hydrolase SARM1 isoform 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q6SZW1]

Yes
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SARM1 forms found in complexes   

SARM1 Component
 Complexes
PR:Q6SZW1ZDASHZ1 hSARM1/iso:1 PR:000036027 sarm:ticam1:ticam2:activated TLR4 complex (human)
PR:000037330 SARM:ticam1:activated TLR3 complex (human)