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Protein Ontology report - ribosomal protein S6 kinase alpha-6
PR:000014287 - http://purl.obolibrary.org/obo/PR_000014287
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000014287   
  PRO nameribosomal protein S6 kinase alpha-6 
  Synonyms
PRO-Short-label: EXACT:RPS6KA6
Gene-based: RELATED:RSK4
Other: EXACT:90 kDa ribosomal protein S6 kinase 6 | p90-RSK 6 | p90RSK6 | pp90RSK4 | ribosomal S6 kinase 4 | RSK-4 | S6K-alpha-6
  Definition"A ribosomal protein S6 kinase alpha that is a translation product of the human RPS6KA6 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000029187 ribosomal protein S6 kinase alpha
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 6                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1530
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000014287
ribosomal protein S6 kinase alpha-6
RPS6KA6
"A ribosomal protein S6 kinase alpha that is a translation product of the human RPS6KA6 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:Q6PFQ0
ribosomal protein S6 kinase alpha-6 (zebrafish)
z-RPS6KA6
"A ribosomal protein S6 kinase alpha-6 that is encoded in the genome of zebrafish." [PRO:DNx]

organism-gene


PR:Q7TPS0
ribosomal protein S6 kinase alpha-6 (mouse)
mRPS6KA6
"A ribosomal protein S6 kinase alpha-6 that is encoded in the genome of mouse." [OMA:MOUSE25189, PRO:DNx]

organism-sequence


PR:E9QK39
ribosomal protein S6 kinase alpha-6 isoform m4 (mouse)
mRPS6KA6/iso:m4
"A ribosomal protein S6 kinase alpha-6 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:E9QK39." [PRO:HJD]

organism-modification


PR:000049868
ribosomal protein S6 kinase alpha-6 isoform m4 phosphorylated 1 (mouse)
mRPS6KA6/iso:m4/Phos:1
"A ribosomal protein S6 kinase alpha-6 isoform m4 (mouse) that has been phosphorylated at position Ser-505. UniProtKB:E9QK39, Ser-505, MOD:00046." [PMID:21183079, PRO:HJD]

organism-sequence


PR:Q7TPS0-1
ribosomal protein S6 kinase alpha-6 isoform m1 (mouse)
mRPS6KA6/iso:m1
"A ribosomal protein S6 kinase alpha-6 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7TPS0-1." [PRO:DNx, UniProtKB:Q7TPS0]

organism-sequence


PR:Q7TPS0-2
ribosomal protein S6 kinase alpha-6 isoform m2 (mouse)
mRPS6KA6/iso:m2
"A ribosomal protein S6 kinase alpha-6 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7TPS0-2." [PRO:DNx, UniProtKB:Q7TPS0]

organism-sequence


PR:Q7TPS0-3
ribosomal protein S6 kinase alpha-6 isoform m3 (mouse)
mRPS6KA6/iso:m3
"A ribosomal protein S6 kinase alpha-6 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7TPS0-3." [PRO:DNx, UniProtKB:Q7TPS0]

organism-gene


PR:Q9UK32
ribosomal protein S6 kinase alpha-6 (human)
hRPS6KA6
"A ribosomal protein S6 kinase alpha-6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UK32]

organism-sequence


PR:Q9UK32-1
ribosomal protein S6 kinase alpha-6 isoform h1 (human)
hRPS6KA6/iso:h1
"A ribosomal protein S6 kinase alpha-6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UK32-1." [PRO:DNx, UniProtKB:Q9UK32]

organism-sequence


PR:Q9UK32-2
ribosomal protein S6 kinase alpha-6 isoform h2 (human)
hRPS6KA6/iso:h2
"A ribosomal protein S6 kinase alpha-6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UK32-2." [PRO:DNx, UniProtKB:Q9UK32]

organism-modification


PR:000049133
ribosomal protein S6 kinase alpha-6 phosphorylated 1 (human)
hRPS6KA6/Phos:1
"A ribosomal protein S6 kinase alpha-6 (human) that has been phosphorylated on residues at positions equivalent to Ser-232, Ser-372, Ser-389, and Thr-581 of the amino acid sequence represented by UniProtKB:Q9UK32-1. Example: UniProtKB:Q9UK32-1, Ser-232/Ser-372/Ser-389, MOD:00046|Thr-581, MOD:00047." [PMID:15632195, PRO:DNx, PRO:KER]
Yes
organism-modification


PR:000049860
ribosomal protein S6 kinase alpha-6 unphosphorylated 1 (human)
hRPS6KA6/UnPhos:1
"A ribosomal protein S6 kinase alpha-6 (human) that lacks phosphorylation on residues at positions equivalent to Ser-232, Ser-372, Ser-389, Thr-581 of the amino acid sequence represented by UniProtKB:Q9UK32-1. Example: UniProtKB:Q9UK32-1, Ser-232/Ser-372/Ser-389/Thr-581, PR:000026291." [PMID:15632195, PRO:KER]

organism-modification


PR:000063107
ribosomal protein S6 kinase alpha-6 phosphorylated 2 (human)
hRPS6KA6/Phos:2
"A ribosomal protein S6 kinase alpha-6 (human) that has been phosphorylated on the residues at the positions equivalent to Thr-368, Ser-372, Ser-389, Thr-581, and Ser-742 of the amino acid sequence represented by UniProtKB:Q9UK32-1. Example: UniProtKB:Q9UK32-1, Thr-368/Thr-581, MOD:00047|Ser-372/Ser-389/Ser-742, MOD:00046." [PRO:DNx, Reactome:R-HSA-9619985]

organism-modification


PR:000063168
ribosomal protein S6 kinase alpha-6 phosphorylated 3 (human)
hRPS6KA6/Phos:3
"A ribosomal protein S6 kinase alpha-6 (human) that has been phosphorylated on the residues at the positions equivalent to Thr-368, Ser-372, and Thr-581 of the amino acid sequence represented by UniProtKB:Q9UK32-1. Example: UniProtKB:Q9UK32-1, Thr-368/Thr-581, MOD:00047|Ser-372, MOD:00046." [PRO:DNx, Reactome:R-HSA-9619958]

organism-modification


PR:000064014
ribosomal protein S6 kinase alpha-6 phosphorylated 4 (human)
hRPS6KA6/Phos:4
"A ribosomal protein S6 kinase alpha-6 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-232, Thr-368, Ser-372, Ser-389, Thr-581, and Ser-742 of the amino acid sequence represented by UniProtKB:Q9UK32-1. Example: UniProtKB:Q9UK32-1, Ser-232/Ser-372/Ser-389/Ser-742, MOD:00046|Thr-368/Thr-581, MOD:00047." [PRO:DNx, Reactome:R-HSA-9619870]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000049133 hRPS6KA6/Phos:1
Example: UniProtKB:Q9UK32-1, Ser-232/Ser-372/Ser-389, MOD:00046|Thr-581, MOD:00047		 enablesincreased GO:0004674 protein serine/threonine kinase activity relative to PR:000049860 hRPS6KA6/UnPhos:1 PMID:15632195