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Protein Ontology report - replication protein A 70 kDa DNA-binding subunit
PR:000014170 - http://purl.obolibrary.org/obo/PR_000014170
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000014170   
  PRO namereplication protein A 70 kDa DNA-binding subunit 
  Synonyms
PRO-Short-label: EXACT:RPA1
Gene-based: RELATED:REPA1 | RPA70
Other: EXACT:replication factor A protein 1 | RF-A protein 1 | RP-A p70
RELATED:single-stranded DNA-binding protein
  Definition"A protein that is a translation product of the human RPA1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 10                                        
         Sequence0                                                  Organism-Sequence 1                                        
         Modification1                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000014170

replication protein A 70 kDa DNA-binding subunit

RPA1


"A protein that is a translation product of the human RPA1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P22336

replication factor A protein 1 (yeast)

yRPA1


"A replication protein A 70 kDa DNA-binding subunit that is encoded in the genome of yeast." [OMA:P22336, PRO:DNx]


organism-gene



PR:P27694

replication protein A 70 kDa DNA-binding subunit (human)

hRPA1


"A replication protein A 70 kDa DNA-binding subunit that is encoded in the genome of human." [PRO:DNx, UniProtKB:P27694]


organism-modification



PR:000026454

replication protein A 70 kDa DNA-binding subunit, initiator methionine removed form (human)

hRPA1/InitMet-


"A replication protein A 70 kDa DNA-binding subunit, initiator methionine removed form in human. UniProtKB:P27694, 2-616." [PRO:DNx]


Yes
organism-modification



PR:000049063

replication protein A 70 kDa DNA-binding subunit, initiator methionine removed sumoylated 1 (human)

hRPA1/InitMet-/Sumo:1


"A replication protein A 70 kDa DNA-binding subunit, initiator methionine removed form (human) that has been post-translationally modified to include sumoylated lysine at positions 449 and 577 of the amino acid sequence represented by UniProtKB:P27694. UniProtKB:P27694, 2-616, Lys-449/Lys-577, MOD:01149." [PRO:DNx, Reactome:R-HSA-4551644]


organism-modification



PR:000066545

replication protein A 70 kDa DNA-binding subunit cysteinylated 1 (human)

hRPA1/Cyst:1


"A replication protein A 70 kDa DNA-binding subunit (human) that has been cysteinylated on the residue at the position equivalent to Cys-476 of the amino acid sequence represented by UniProtKB:P27694. UniProtKB:P27694, Cys-476, MOD:00765." [IEDB_epitope:1593867, PRO:DNx]


organism-modification



PR:000067834

replication protein A 70 kDa DNA-binding subunit methylated 1 (human)

hRPA1/Me:1


"A replication protein A 70 kDa DNA-binding subunit (human) that has been methylated on the residue at the position equivalent to Cys-200 of the amino acid sequence represented by UniProtKB:P27694. UniProtKB:P27694, Cys-200, MOD:00660." [IEDB_epitope:1055203, PRO:DNx]


organism-modification



PR:000076405

replication protein A 70 kDa DNA-binding subunit cysteinylated 2 (human)

hRPA1/Cyst:2


"A replication protein A 70 kDa DNA-binding subunit (human) that has been cysteinylated on the residue at the position equivalent to Cys-531 of the amino acid sequence represented by UniProtKB:P27694. UniProtKB:P27694, Cys-531, MOD:00765." [IEDB_epitope:881936, PRO:DNx]


organism-modification



PR:000076416

replication protein A 70 kDa DNA-binding subunit methylated 2 (human)

hRPA1/Me:2


"A replication protein A 70 kDa DNA-binding subunit (human) that has been methylated on the residue at the position equivalent to Cys-289 of the amino acid sequence represented by UniProtKB:P27694. UniProtKB:P27694, Cys-289, MOD:00660." [IEDB_epitope:1033786, IEDB_epitope:1033787, PRO:DNx]


organism-gene



PR:Q19537

probable replication factor A 73 kDa subunit (worm)

RPA1 (worm)


"A replication protein A 70 kDa DNA-binding subunit that is encoded in the genome of worm." [OMA:Q19537, PRO:DNx]


organism-gene



PR:Q24492

replication protein A 70 kDa DNA-binding subunit (fruit fly)

fly-RPA1


"A replication protein A 70 kDa DNA-binding subunit that is encoded in the genome of fruit fly." [OMA:Q24492, PRO:DNx]


organism-gene



PR:Q54HE3

uncharacterized protein, rfa1 translation product (Dictyostelium discoideum)

Dicty-RPA1


"A replication protein A 70 kDa DNA-binding subunit that is encoded in the genome of Dictyostelium discoideum." [PANTHER:PTHR23273:SF0, PRO:DNx]


organism-gene



PR:Q5ZJJ2

replication protein A 70 kDa DNA-binding subunit (chicken)

chick-RPA1


"A replication protein A 70 kDa DNA-binding subunit that is encoded in the genome of chicken." [OMA:Q5ZJJ2, PRO:DNx]


organism-gene



PR:Q6NY74

replication protein A 70 kDa DNA-binding subunit (zebrafish)

z-RPA1


"A replication protein A 70 kDa DNA-binding subunit that is encoded in the genome of zebrafish." [OMA:Q6NY74, PRO:DNx]


organism-gene



PR:Q8VEE4

replication protein A 70 kDa DNA-binding subunit (mouse)

mRPA1


"A replication protein A 70 kDa DNA-binding subunit that is encoded in the genome of mouse." [OMA:Q8VEE4, PRO:DNx]


organism-gene



PR:Q92372

replication factor A protein 1 (Schizosaccharomyces pombe 972h-)

Spom972h-RPA1


"A replication protein A 70 kDa DNA-binding subunit that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q92372, PRO:DNx]


organism-gene



PR:Q9SKI4

replication protein A 70 kDa DNA-binding subunit A (Arabidopsis thaliana)

At-RPA1


"A replication protein A 70 kDa DNA-binding subunit that is encoded in the genome of Arabidopsis thaliana." [PRO:DNx]


organism-sequence



PR:Q9SKI4-1

replication protein A 70 kDa DNA-binding subunit A isoform 1 (Arabidopsis thaliana)

At-RPA1/iso:1


"A replication protein A 70 kDa DNA-binding subunit A (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9SKI4-1." [PRO:DNx, UniProtKB:Q9SKI4]


modification



PR:000021284

replication protein A 70 kDa DNA-binding subunit, initiator methionine removed form

RPA1/InitMet-


"A replication protein A 70 kDa DNA-binding subunit that has had the initiator methionine removed." [PRO:DNx]


organism-modification



PR:000026454

replication protein A 70 kDa DNA-binding subunit, initiator methionine removed form (human)

hRPA1/InitMet-


"A replication protein A 70 kDa DNA-binding subunit, initiator methionine removed form in human. UniProtKB:P27694, 2-616." [PRO:DNx]


Yes
organism-modification



PR:000049063

replication protein A 70 kDa DNA-binding subunit, initiator methionine removed sumoylated 1 (human)

hRPA1/InitMet-/Sumo:1


"A replication protein A 70 kDa DNA-binding subunit, initiator methionine removed form (human) that has been post-translationally modified to include sumoylated lysine at positions 449 and 577 of the amino acid sequence represented by UniProtKB:P27694. UniProtKB:P27694, 2-616, Lys-449/Lys-577, MOD:01149." [PRO:DNx, Reactome:R-HSA-4551644]


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RPA1 forms found in complexes   

RPA1 Component
Complexes
PR:000026454 hRPA1/InitMet- PR:000026458 DNA replication factor A complex (human)