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Protein Ontology report - peroxisome proliferator-activated receptor gamma
PR:000013058 - http://purl.obolibrary.org/obo/PR_000013058
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000013058   
  PRO nameperoxisome proliferator-activated receptor gamma 
  Synonyms
PRO-Short-label: EXACT:PPARG
Gene-based: RELATED:NR1C3
Other: EXACT:nuclear receptor subfamily 1 group C member 3 | PPAR-gamma
  Definition"A protein that is a translation product of the human PPARG gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 7                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:595
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000013058

peroxisome proliferator-activated receptor gamma

PPARG


"A protein that is a translation product of the human PPARG gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O88275

peroxisome proliferator-activated receptor gamma (rat)

rPPARG


"A peroxisome proliferator-activated receptor gamma that is encoded in the genome of rat." [OMA:O88275, PRO:DNx]


organism-sequence



PR:O88275-1

peroxisome proliferator-activated receptor gamma isoform 2 (rat)

rPPARG/iso:2


"A peroxisome proliferator-activated receptor gamma isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:O88275-2

peroxisome proliferator-activated receptor gamma isoform r1 (rat)

rPPARG/iso:r1


"A peroxisome proliferator-activated receptor gamma (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88275-2." [PRO:DNx, UniProtKB:O88275]


organism-gene



PR:P37231

peroxisome proliferator-activated receptor gamma (human)

hPPARG


"A peroxisome proliferator-activated receptor gamma that is encoded in the genome of human." [PRO:DNx, UniProtKB:P37231]


organism-sequence



PR:P37231-1

peroxisome proliferator-activated receptor gamma isoform 2 (human)

hPPARG/iso:2


"A peroxisome proliferator-activated receptor gamma isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000085986

peroxisome proliferator-activated receptor gamma isoform 2 phosphorylated 1 (human)

hPPARG/iso:2/Phos:1


"A peroxisome proliferator-activated receptor gamma isoform 2 (human) that has been phosphorylated on the residues at the positions equivalent to Tyr-78 and Tyr-102 of the amino acid sequence represented by UniProtKB:P37231-1. UniProtKB:P37231-1, Tyr-78/Tyr-102, MOD:00048." [PRO:DNx, Reactome:R-HSA-9842025]


organism-sequence



PR:P37231-2

peroxisome proliferator-activated receptor gamma isoform h1 (human)

hPPARG/iso:h1


"A peroxisome proliferator-activated receptor gamma (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P37231-2." [PRO:DNx, UniProtKB:P37231]


organism-sequence



PR:P37231-3

peroxisome proliferator-activated receptor gamma isoform h3 (human)

hPPARG/iso:h3


"A peroxisome proliferator-activated receptor gamma (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P37231-3." [PRO:DNx, UniProtKB:P37231]


organism-modification



PR:000064839

peroxisome proliferator-activated receptor gamma sumoylated 1 (human)

hPPARG/Sumo:1


"A peroxisome proliferator-activated receptor gamma (human) that has been sumoylated on the residues at the positions equivalent to Lys-107 and Lys-395 of the amino acid sequence represented by UniProtKB:P37231-1. Example: UniProtKB:P37231-1, Lys-107/Lys-395, MOD:01149." [PRO:DNx, Reactome:R-HSA-4717444]


organism-modification



PR:000070545

peroxisome proliferator-activated receptor gamma deaminated 1 (human)

hPPARG/Deam:1


"A peroxisome proliferator-activated receptor gamma (human) that has been deaminated on the residue at the position equivalent to Gln-443 of the amino acid sequence represented by UniProtKB:P37231-1. Example: UniProtKB:P37231-1, Gln-443, MOD:00685." [IEDB_epitope:1987544, PRO:DNx]


organism-gene



PR:P37238

peroxisome proliferator-activated receptor gamma (mouse)

mPPARG


"A peroxisome proliferator-activated receptor gamma that is encoded in the genome of mouse." [OMA:P37238, PRO:DNx]


organism-sequence



PR:P37238-1

peroxisome proliferator-activated receptor gamma isoform m2 (mouse)

mPPARG/iso:m2


"A peroxisome proliferator-activated receptor gamma (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P37238-1." [PRO:DNx, UniProtKB:P37238]


organism-sequence



PR:P37238-2

peroxisome proliferator-activated receptor gamma isoform 1 (mouse)

mPPARG/iso:1


"A peroxisome proliferator-activated receptor gamma (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P37238-2." [PRO:DNx, UniProtKB:P37238]

Yes

organism-modification



PR:000045768

peroxisome proliferator-activated receptor gamma phosphorylated 1 (mouse)

mPPARG/Phos:1


"A peroxisome proliferator-activated receptor gamma (mouse) that has been phosphorylated on the residue at the position equivalent to Ser-112 of the amino acid sequence represented by UniProtKB:P37238-1. Example: UniProtKB:P37238-1, Ser-112, MOD:00046." [iPTMnet:P37238, PMID:14536066]


organism-gene



PR:P41830

steroid hormone receptor family member cnr14 (worm)

PPARG (worm)


"A peroxisome proliferator-activated receptor gamma that is encoded in the genome of worm." [OMA:P41830, PRO:DNx]


sequence



PR:000039376

peroxisome proliferator-activated receptor gamma isoform 1

PPARG/iso:1


"A peroxisome proliferator-activated receptor gamma that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P37231-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:O88275-1

peroxisome proliferator-activated receptor gamma isoform 2 (rat)

rPPARG/iso:2


"A peroxisome proliferator-activated receptor gamma isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P37231-1

peroxisome proliferator-activated receptor gamma isoform 2 (human)

hPPARG/iso:2


"A peroxisome proliferator-activated receptor gamma isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000085986

peroxisome proliferator-activated receptor gamma isoform 2 phosphorylated 1 (human)

hPPARG/iso:2/Phos:1


"A peroxisome proliferator-activated receptor gamma isoform 2 (human) that has been phosphorylated on the residues at the positions equivalent to Tyr-78 and Tyr-102 of the amino acid sequence represented by UniProtKB:P37231-1. UniProtKB:P37231-1, Tyr-78/Tyr-102, MOD:00048." [PRO:DNx, Reactome:R-HSA-9842025]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P37238-2 mPPARG/iso:1 acts_upstream_of_or_withinGO:0045444 fat cell differentiation MGI_ref:5528597; PMID:23840343
GO:0045600 positive regulation of fat cell differentiation MGI_ref:5309089; PMID:22226965
GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:5309089; PMID:22226965