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Protein Ontology report - POU domain, class 5, transcription factor 1
PR:000013044 - http://purl.obolibrary.org/obo/PR_000013044
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000013044   
  PRO namePOU domain, class 5, transcription factor 1 
  Synonyms
PRO-Short-label: EXACT:POU5F1
Gene-based: RELATED:OCT3 | OCT4 | OTF3
Other: EXACT:NF-A3 | Oct-3 | Oct-4 | octamer-binding protein 3 | octamer-binding protein 4 | octamer-binding transcription factor 3 | OTF-3
  Definition"A protein that is a translation product of the human POU5F1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 1                                        
         Sequence1                                                  Organism-Sequence 3                                        
         Modification2                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000013044
POU domain, class 5, transcription factor 1
POU5F1
"A protein that is a translation product of the human POU5F1 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:Q01860
POU domain, class 5, transcription factor 1 (human)
hPOU5F1
"A POU domain, class 5, transcription factor 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q01860]

organism-sequence


PR:Q01860-1
POU domain, class 5, transcription factor 1 isoform 1 (human)
hPOU5F1/iso:1
"A POU domain, class 5, transcription factor 1 isoform 1 that is encoded in the genome of human." [PMID:1972777, PRO:HJD]

organism-sequence


PR:Q01860-2
POU domain, class 5, transcription factor 1 isoform B (human)
hPOU5F1/iso:B
"A POU domain, class 5, transcription factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01860-2." [PRO:DNx, UniProtKB:Q01860]

sequence


PR:000037048
POU domain, class 5, transcription factor 1 isoform 1
POU5F1/iso:1
"A POU domain, class 5, transcription factor 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20263-1 or a 1:1 ortholog thereof." [PMID:1972777, PRO:HJD]

organism-sequence


PR:P20263-1
POU domain, class 5, transcription factor 1 isoform 1 (mouse)
mPOU5F1/iso:1
"A POU domain, class 5, transcription factor 1 isoform 1 that is encoded in the genome of mouse." [PMID:1972777, PRO:HJD]
Yes
organism-modification


PR:000037051
POU domain, class 5, transcription factor 1 isoform 1 phosphorylated 1 (mouse)
mPOU5F1/iso:1/Phos:1
"A POU domain, class 5, transcription factor 1 isoform 1 phosphorylated 1 in mouse. UniProtKB:P20263-1, Thr-228, MOD:00047." [PMID:23495099, PRO:HJD]
Yes
organism-modification


PR:000049954
POU domain, class 5, transcription factor 1 isoform 1 unphosphorylated 1 (mouse)
mPOU5F1/iso:1/UnPhos:1
"A POU domain, class 5, transcription factor 1 isoform 1 unphosphorylated 1 in mouse. UniProtKB:P20263-1, Thr-228, PR:000026291." [PMID:23495099, PRO:HJD]

organism-sequence


PR:Q01860-1
POU domain, class 5, transcription factor 1 isoform 1 (human)
hPOU5F1/iso:1
"A POU domain, class 5, transcription factor 1 isoform 1 that is encoded in the genome of human." [PMID:1972777, PRO:HJD]

modification


PR:000037050
POU domain, class 5, transcription factor 1 isoform 1 phosphorylated 1
POU5F1/iso:1/Phos:1
"A POU domain, class 5, transcription factor 1 isoform 1 that is phosphorylated on a Thr residue within the conserved sequence RKRKRTS located in the protein dimerization domain. Example: UniProtKB:P20263-1, Thr-228, MOD:00047." [PMID:23495099, PRO:HJD]

organism-modification


PR:000037051
POU domain, class 5, transcription factor 1 isoform 1 phosphorylated 1 (mouse)
mPOU5F1/iso:1/Phos:1
"A POU domain, class 5, transcription factor 1 isoform 1 phosphorylated 1 in mouse. UniProtKB:P20263-1, Thr-228, MOD:00047." [PMID:23495099, PRO:HJD]
Yes
modification


PR:000049955
POU domain, class 5, transcription factor 1 isoform 1 unphosphorylated 1
POU5F1/iso:1/UnPhos:1
"A POU domain, class 5, transcription factor 1 isoform 1 that lacks phosphorylation on the Thr residue within the conserved sequence RKRKRTS located in the protein dimerization domain. Example: UniProtKB:P20263-1, Thr-228, PR:000026291." [PMID:23495099, PRO:HJD]

organism-modification


PR:000049954
POU domain, class 5, transcription factor 1 isoform 1 unphosphorylated 1 (mouse)
mPOU5F1/iso:1/UnPhos:1
"A POU domain, class 5, transcription factor 1 isoform 1 unphosphorylated 1 in mouse. UniProtKB:P20263-1, Thr-228, PR:000026291." [PMID:23495099, PRO:HJD]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000037051 mPOU5F1/iso:1/Phos:1
UniProtKB:P20263-1, Thr-228, MOD:00047		 acts_upstream_of_or_withinGO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction MGI_ref:5490149; PMID:23495099
PR:P20263-1 mPOU5F1/iso:1 acts_upstream_of_or_withinGO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction MGI_ref:5490149; PMID:23495099