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Protein Ontology report - 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
PR:000012837 - http://purl.obolibrary.org/obo/PR_000012837
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000012837   
  PRO name1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 
  Synonyms
PRO-Short-label: EXACT:PLCG2
Other: EXACT:phosphoinositide phospholipase C-gamma-2 | phospholipase C-gamma-2 | phospholipase C-IV | PLC-gamma-2 | PLC-IV
  Definition"A phospholipase C-gamma that is a translation product of the human PLCG2 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000050049 phospholipase C-gamma
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 10                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1408
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000012837
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
PLCG2
"A phospholipase C-gamma that is a translation product of the human PLCG2 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P16885
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (human)
hPLCG2
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P16885]

organism-sequence


PR:P16885-1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 (human)
hPLCG2/iso:1
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-modification


PR:000048809
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 phosphorylated form (human)
hPLCG2/PhosRes+
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (human) that includes at least one phosphorylated residue. UniProtKB:P16885, MOD:00696." [PRO:DNx, Reactome:R-HSA-114602]

organism-modification


PR:000048806
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 phosphorylated 1 (human)
hPLCG2/Phos:1
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (human) that has been post-translationally modified to include phosphotyrosine at positions 753 and 759 of the amino acid sequence represented by UniProtKB:P16885. UniProtKB:P16885, Tyr-753/Tyr-759, MOD:00048." [PRO:DNx, Reactome:R-HSA-5607631, Reactome:R-HSA-5607640]

organism-modification


PR:000048807
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 phosphorylated 2 (human)
hPLCG2/Phos:2
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (human) that has been post-translationally modified to include phosphotyrosine at positions 753, 759, 1197 and 1217 of the amino acid sequence represented by UniProtKB:P16885. UniProtKB:P16885, Tyr-753/Tyr-759/Tyr-1197/Tyr-1217, MOD:00048." [PRO:DNx, Reactome:R-HSA-2685601]

organism-modification


PR:000048808
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 phosphorylated 3 (human)
hPLCG2/Phos:3
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (human) that has been post-translationally modified to include phosphotyrosine at positions 753, 759 and 1217 of the amino acid sequence represented by UniProtKB:P16885. UniProtKB:P16885, Tyr-753/Tyr-759/Tyr-1217, MOD:00048." [PRO:DNx, Reactome:R-HSA-984816]

organism-modification


PR:000062980
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 phosphotyrosine form (human)
hPLCG2/PhosTyr+
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (human) that includes at least one phosphorylated tyrosine. UniProtKB:P16885, MOD:00048." [PRO:DNx, Reactome:R-HSA-9029105]

organism-modification


PR:000066166
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 methylated 1 (human)
hPLCG2/Me:1
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (human) that has been methylated on the residue at the position equivalent to Cys-348 of the amino acid sequence represented by UniProtKB:P16885. UniProtKB:P16885, Cys-348, MOD:00660." [IEDB_epitope:1050537, PRO:DNx]

organism-modification


PR:000068143
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 cysteinylated 1 (human)
hPLCG2/Cyst:1
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-1200 of the amino acid sequence represented by UniProtKB:P16885. UniProtKB:P16885, Cys-1200, MOD:00765." [IEDB_epitope:1568196, PRO:DNx]

organism-modification


PR:000069203
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 cysteinylated 2 (human)
hPLCG2/Cyst:2
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-624 of the amino acid sequence represented by UniProtKB:P16885. UniProtKB:P16885, Cys-624, MOD:00765." [IEDB_epitope:1573418, PRO:DNx]

organism-gene


PR:P24135
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (rat)
rPLCG2
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 that is encoded in the genome of rat." [OMA:P24135, PRO:DNx]

organism-sequence


PR:P24135-1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 (rat)
rPLCG2/iso:1
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]

organism-gene


PR:Q8CIH5
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (mouse)
mPLCG2
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 that is encoded in the genome of mouse." [OMA:Q8CIH5, PRO:DNx]

organism-sequence


PR:Q8CIH5-1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 (mouse)
mPLCG2/iso:1
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

organism-modification


PR:000049797
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 phosphorylated 1 (mouse)
mPLCG2/iso:1/Phos:1
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 (mouse) that has been phosphorylated on Tyr-759. UniProtKB:Q8CIH5-1, Tyr-759, MOD:00048." [PMID:27609517, PRO:LN]

organism-modification


PR:000049798
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 phosphorylated 2 (mouse)
mPLCG2/iso:1/Phos:2
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 (mouse) that has been phosphorylated on Tyr-1217. UniProtKB:Q8CIH5-1, Tyr-1217, MOD:00048." [PMID:27609517, PRO:LN]

sequence


PR:000038964
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1
PLCG2/iso:1
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16885-1 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P16885-1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 (human)
hPLCG2/iso:1
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:P24135-1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 (rat)
rPLCG2/iso:1
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]

organism-sequence


PR:Q8CIH5-1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 (mouse)
mPLCG2/iso:1
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

organism-modification


PR:000049797
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 phosphorylated 1 (mouse)
mPLCG2/iso:1/Phos:1
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 (mouse) that has been phosphorylated on Tyr-759. UniProtKB:Q8CIH5-1, Tyr-759, MOD:00048." [PMID:27609517, PRO:LN]

organism-modification


PR:000049798
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 phosphorylated 2 (mouse)
mPLCG2/iso:1/Phos:2
"A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform 1 (mouse) that has been phosphorylated on Tyr-1217. UniProtKB:Q8CIH5-1, Tyr-1217, MOD:00048." [PMID:27609517, PRO:LN]