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Protein Ontology report - pyruvate kinase PKM
PR:000012783 - http://purl.obolibrary.org/obo/PR_000012783
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000012783   
  PRO namepyruvate kinase PKM 
  Synonyms
PRO-Short-label: EXACT:PKM
Gene-based: RELATED:OIP3 | PK2 | PK3 | PKM2 | Pykm
Other: EXACT:CTHBP | cytosolic thyroid hormone-binding protein | OIP-3 | Opa-interacting protein 3 | pyruvate kinase 2/3 | pyruvate kinase isozymes M1/M2 | pyruvate kinase muscle isozyme | THBP1 | threonine-protein kinase PKM2 | thyroid hormone-binding protein 1 | tumor M2-PK | tyrosine-protein kinase PKM2
  Definition"A protein that is a translation product of the human PKM gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence2                                                  Organism-Sequence 9                                        
         Modification1                                                  Organism-Modification 8                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000012783
pyruvate kinase PKM
PKM
"A protein that is a translation product of the human PKM gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:O62619
pyruvate kinase (fruit fly)
fly-PKM
"A pyruvate kinase PKM that is encoded in the genome of fruit fly." [OMA:O62619, PRO:DNx]

organism-sequence


PR:O62619-1
pyruvate kinase isoform A (fruit fly)
fly-PKM/iso:A
"A pyruvate kinase (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O62619-1." [PRO:DNx, UniProtKB:O62619]

organism-sequence


PR:O62619-2
pyruvate kinase isoform B (fruit fly)
fly-PKM/iso:B
"A pyruvate kinase (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O62619-2." [PRO:DNx, UniProtKB:O62619]

organism-gene


PR:P00548
pyruvate kinase PKM (chicken)
chick-PKM
"A pyruvate kinase PKM that is encoded in the genome of chicken." [OMA:P00548, PRO:DNx]

organism-gene


PR:P11980
pyruvate kinase PKM (rat)
rPKM
"A pyruvate kinase PKM that is encoded in the genome of rat." [OMA:P11980, PRO:DNx]

organism-sequence


PR:P11980-1
pyruvate kinase PKM isoform M1 (rat)
rPkm/iso:M1
"A pyruvate kinase PKM (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P11980-1." [PRO:DNx, UniProtKB:P11980]

organism-sequence


PR:P11980-2
pyruvate kinase PKM isoform rM2 (rat)
rPKM/iso:rM2
"A pyruvate kinase PKM (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P11980-2." [PRO:DNx, UniProtKB:P11980]

organism-gene


PR:P14618
pyruvate kinase PKM (human)
hPKM
"A pyruvate kinase PKM that is encoded in the genome of human." [PRO:DNx, UniProtKB:P14618]

organism-sequence


PR:P14618-1
pyruvate kinase PKM isoform M2 (human)
hPKM/iso:M2
"A pyruvate kinase PKM isoform M2 that is encoded in the genome of human." [PRO:DNx]

organism-modification


PR:000062561
pyruvate kinase PKM isoform M2, initiator methionine removed form (human)
hPKM/iso:M2/InitMet-
"A pyruvate kinase PKM isoform M2 (human) that has had the initiator methionine removed. UniProtKB:P14618-1, 2-531." [PRO:DNx, Reactome:R-HSA-71667]

organism-sequence


PR:P14618-2
pyruvate kinase PKM isoform M1 (human)
hPKM/iso:M1
"A pyruvate kinase PKM isoform M1 that is encoded in the genome of human." [PRO:DNx]

organism-modification


PR:000063103
pyruvate kinase PKM isoform M1, initiator methionine removed form (human)
hPKM/iso:M1/InitMet-
"A pyruvate kinase PKM isoform M1 (human) that has had the initiator methionine removed. UniProtKB:P14618-2, 2-531." [PRO:DNx, Reactome:R-HSA-450658]

organism-sequence


PR:P14618-3
pyruvate kinase PKM isoform h3 (human)
hPKM/iso:h3
"A pyruvate kinase PKM (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14618-3." [PRO:DNx, UniProtKB:P14618]

organism-modification


PR:000045679
pyruvate kinase PKM phosphorylated 1 (human)
hPKM/Phos:1
"A pyruvate kinase PKM (human) that has been phosphorylated on the residue at the position equivalent to Ser-37 of the amino acid sequence represented by UniProtKB:P14618-1. Example: UniProtKB:P14618-1, Ser-37, MOD:00046." [iPTMnet:P14618, PMID:23178880]

organism-modification


PR:000062456
pyruvate kinase PKM, initiator methionine removed form (human)
hPKM/InitMet-
"A pyruvate kinase PKM (human) that has had the initiator methionine removed. Example: UniProtKB:P14618-1, 2-531." [PRO:DNx, Reactome:R-HSA-6801387, Reactome:R-HSA-6801401, Reactome:R-HSA-6806491]

organism-modification


PR:000062561
pyruvate kinase PKM isoform M2, initiator methionine removed form (human)
hPKM/iso:M2/InitMet-
"A pyruvate kinase PKM isoform M2 (human) that has had the initiator methionine removed. UniProtKB:P14618-1, 2-531." [PRO:DNx, Reactome:R-HSA-71667]

organism-modification


PR:000063103
pyruvate kinase PKM isoform M1, initiator methionine removed form (human)
hPKM/iso:M1/InitMet-
"A pyruvate kinase PKM isoform M1 (human) that has had the initiator methionine removed. UniProtKB:P14618-2, 2-531." [PRO:DNx, Reactome:R-HSA-450658]

organism-modification


PR:000065901
pyruvate kinase PKM cysteinylated 1 (human)
hPKM/Cyst:1
"A pyruvate kinase PKM (human) that has been cysteinylated on the residue at the position equivalent to Cys-358 of the amino acid sequence represented by UniProtKB:P14618-1. Example: UniProtKB:P14618-1, Cys-358, MOD:00765." [IEDB_epitope:1003360, PRO:DNx]

organism-modification


PR:000074942
pyruvate kinase PKM methylated 1 (human)
hPKM/Me:1
"A pyruvate kinase PKM (human) that has been methylated on the residue at the position equivalent to Cys-424 of the amino acid sequence represented by UniProtKB:P14618-1. Example: UniProtKB:P14618-1, Cys-424, MOD:00660." [IEDB_epitope:1004269, PRO:DNx]

organism-modification


PR:000077078
pyruvate kinase PKM cysteinylated 2 (human)
hPKM/Cyst:2
"A pyruvate kinase PKM (human) that has been cysteinylated on the residue at the position equivalent to Cys-326 of the amino acid sequence represented by UniProtKB:P14618-1. Example: UniProtKB:P14618-1, Cys-326, MOD:00765." [IEDB_epitope:2123302, PRO:DNx]

organism-gene


PR:P52480
pyruvate kinase PKM (mouse)
mPKM
"A pyruvate kinase PKM that is encoded in the genome of mouse." [OMA:P52480, PRO:DNx]

organism-sequence


PR:P52480-1
pyruvate kinase PKM isoform M2 (mouse)
mPKM/iso:M2
"A pyruvate kinase PKM isoform M2 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:P52480-2
pyruvate kinase PKM isoform M1 (mouse)
mPKM/iso:M1
"A pyruvate kinase PKM isoform M1 that is encoded in the genome of mouse." [PRO:DNx]

organism-modification


PR:000077443
pyruvate kinase PKM deaminated 1 (mouse)
mPKM/Deam:1
"A pyruvate kinase PKM (mouse) that has been deaminated on the residue at the position equivalent to Asn-199 of the amino acid sequence represented by UniProtKB:P52480-1. Example: UniProtKB:P52480-1, Asn-199, MOD:00684." [IEDB_epitope:2135666, PRO:DNx]

sequence


PR:000038907
pyruvate kinase PKM isoform M2
PKM/iso:1
"A pyruvate kinase PKM that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14618-1 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P14618-1
pyruvate kinase PKM isoform M2 (human)
hPKM/iso:M2
"A pyruvate kinase PKM isoform M2 that is encoded in the genome of human." [PRO:DNx]

organism-modification


PR:000062561
pyruvate kinase PKM isoform M2, initiator methionine removed form (human)
hPKM/iso:M2/InitMet-
"A pyruvate kinase PKM isoform M2 (human) that has had the initiator methionine removed. UniProtKB:P14618-1, 2-531." [PRO:DNx, Reactome:R-HSA-71667]

organism-sequence


PR:P52480-1
pyruvate kinase PKM isoform M2 (mouse)
mPKM/iso:M2
"A pyruvate kinase PKM isoform M2 that is encoded in the genome of mouse." [PRO:DNx]

sequence


PR:000038908
pyruvate kinase PKM isoform M1
PKM/iso:2
"A pyruvate kinase PKM that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14618-2 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P14618-2
pyruvate kinase PKM isoform M1 (human)
hPKM/iso:M1
"A pyruvate kinase PKM isoform M1 that is encoded in the genome of human." [PRO:DNx]

organism-modification


PR:000063103
pyruvate kinase PKM isoform M1, initiator methionine removed form (human)
hPKM/iso:M1/InitMet-
"A pyruvate kinase PKM isoform M1 (human) that has had the initiator methionine removed. UniProtKB:P14618-2, 2-531." [PRO:DNx, Reactome:R-HSA-450658]

organism-sequence


PR:P52480-2
pyruvate kinase PKM isoform M1 (mouse)
mPKM/iso:M1
"A pyruvate kinase PKM isoform M1 that is encoded in the genome of mouse." [PRO:DNx]

modification


PR:000020982
pyruvate kinase PKM, initiator methionine removed form
PKM/InitMet-
"A pyruvate kinase PKM that has had the initiator methionine removed." [PRO:DNx]

organism-modification


PR:000062456
pyruvate kinase PKM, initiator methionine removed form (human)
hPKM/InitMet-
"A pyruvate kinase PKM (human) that has had the initiator methionine removed. Example: UniProtKB:P14618-1, 2-531." [PRO:DNx, Reactome:R-HSA-6801387, Reactome:R-HSA-6801401, Reactome:R-HSA-6806491]

organism-modification


PR:000062561
pyruvate kinase PKM isoform M2, initiator methionine removed form (human)
hPKM/iso:M2/InitMet-
"A pyruvate kinase PKM isoform M2 (human) that has had the initiator methionine removed. UniProtKB:P14618-1, 2-531." [PRO:DNx, Reactome:R-HSA-71667]

organism-modification


PR:000063103
pyruvate kinase PKM isoform M1, initiator methionine removed form (human)
hPKM/iso:M1/InitMet-
"A pyruvate kinase PKM isoform M1 (human) that has had the initiator methionine removed. UniProtKB:P14618-2, 2-531." [PRO:DNx, Reactome:R-HSA-450658]