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Protein Ontology report - profilin-1
PR:000012585 - http://purl.obolibrary.org/obo/PR_000012585
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000012585   
  PRO nameprofilin-1 
  Synonyms
PRO-Short-label: EXACT:PFN1
Other: EXACT:profilin I
  Definition"A profilin that is a translation product of the human PFN1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000050050 profilin
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification2                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000012585

profilin-1

PFN1


"A profilin that is a translation product of the human PFN1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P07737

profilin-1 (human)

hPFN1


"A profilin-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07737]


organism-sequence



PR:P07737-1

profilin-1 isoform 1 (human)

hPFN1/iso:1


"A profilin-1 isoform 1 that is encoded in the genome of human." [PMID:18829504, SALO:AJ]

Yes

organism-modification



PR:000048752

profilin-1, initiator methionine removed form (human)

hPFN1/InitMet-


"A profilin-1 (human) that has had the initiator methionine removed. UniProtKB:P07737, 2-140." [PRO:DNx, Reactome:R-HSA-203081, Reactome:R-HSA-350755]


organism-modification



PR:000068365

profilin-1 deaminated 1 (human)

hPFN1/Deam:1


"A profilin-1 (human) that has been deaminated on the residue at the position equivalent to Gln-80 of the amino acid sequence represented by UniProtKB:P07737. UniProtKB:P07737, Gln-80, MOD:00685." [IEDB_epitope:1566124, PRO:DNx]


organism-modification



PR:000081709

profilin-1 methylated 1 (human)

hPFN1/Me:1


"A profilin-1 (human) that has been methylated on the residue at the position equivalent to Cys-128 of the amino acid sequence represented by UniProtKB:P07737. UniProtKB:P07737, Cys-128, MOD:00660." [IEDB_epitope:1004412, PRO:DNx]


organism-modification



PR:000083329

profilin-1 cysteinylated 1 (human)

hPFN1/Cyst:1


"A profilin-1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-128 of the amino acid sequence represented by UniProtKB:P07737. UniProtKB:P07737, Cys-128, MOD:00765." [IEDB_epitope:2122164, PRO:DNx]


organism-gene



PR:P62962

profilin-1 (mouse)

mPFN1


"A profilin-1 that is encoded in the genome of mouse." [OMA:P62962, PRO:DNx]


organism-sequence



PR:P62962-1

profilin-1 isoform 1 (mouse)

mPFN1/iso:1


"A profilin-1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-gene



PR:P62963

profilin-1 (rat)

rPFN1


"A profilin-1 that is encoded in the genome of rat." [OMA:P62963, PRO:DNx]


sequence



PR:000025644

profilin-1 isoform 1

PFN1/iso:1


"A profilin-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07737-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:P07737-1

profilin-1 isoform 1 (human)

hPFN1/iso:1


"A profilin-1 isoform 1 that is encoded in the genome of human." [PMID:18829504, SALO:AJ]

Yes

organism-sequence



PR:P62962-1

profilin-1 isoform 1 (mouse)

mPFN1/iso:1


"A profilin-1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


modification



PR:000026622

profilin-1 isoform 1, initiator methionine removed form

PFN1/iso:1/InitMet-


"A profilin-1 isoform 1 that has had the initiator methionine removed." [PRO:DNx]


modification



PR:000020937

profilin-1, initiator methionine removed form

PFN1/InitMet-


"A profilin-1 that has had the initiator methionine removed." [PRO:DNx]


modification



PR:000026622

profilin-1 isoform 1, initiator methionine removed form

PFN1/iso:1/InitMet-


"A profilin-1 isoform 1 that has had the initiator methionine removed." [PRO:DNx]


organism-modification



PR:000048752

profilin-1, initiator methionine removed form (human)

hPFN1/InitMet-


"A profilin-1 (human) that has had the initiator methionine removed. UniProtKB:P07737, 2-140." [PRO:DNx, Reactome:R-HSA-203081, Reactome:R-HSA-350755]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P07737-1 hPFN1/iso:1 located_inCHEBI:59163 biomarker PMID:18829504