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Protein Ontology report - ATP-dependent 6-phosphofructokinase, liver type
PR:000012582 - http://purl.obolibrary.org/obo/PR_000012582
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000012582   
  PRO nameATP-dependent 6-phosphofructokinase, liver type 
  Synonyms
PRO-Short-label: EXACT:PFKL
Gene-based: RELATED:Pfk-l | Pfkb
Other: EXACT:6-phosphofructokinase type B | PFK-B | phosphofructo-1-kinase isozyme B
  Definition"A Boreoeutherial-type ATP-dependent 6-phosphofructokinase that is a translation product of the human PFKL gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000050099 Boreoeutherial-type ATP-dependent 6-phosphofructokinase
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 3                                        
         Modification4                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000012582
ATP-dependent 6-phosphofructokinase, liver type
PFKL
"A Boreoeutherial-type ATP-dependent 6-phosphofructokinase that is a translation product of the human PFKL gene or a 1:1 ortholog thereof." [PRO:DNx]

Yes
organism-gene


PR:P12382
ATP-dependent 6-phosphofructokinase, liver type (mouse)
mPFKL
"An ATP-dependent 6-phosphofructokinase, liver type that is encoded in the genome of mouse." [OMA:P12382, PRO:DNx]

organism-sequence


PR:P12382-1
ATP-dependent 6-phosphofructokinase, liver type isoform 1 (mouse)
mPFKL/iso:1
"An ATP-dependent 6-phosphofructokinase, liver type isoform 1 that is encoded in the genome of mouse." [PMID:18034455, PMID:19131326, PMID:296989, PRO:HJD]

Yes
organism-modification


PR:000026468
ATP-dependent 6-phosphofructokinase, liver type isoform 1 phosphorylated 1 (mouse)
mPFKL/iso:1/Phos:1
"An ATP-dependent 6-phosphofructokinase, liver type isoform 1 phosphorylated 1 in mouse. UniProtKB:P12382-1, Tyr-640, MOD:00048." [PMID:18034455, PRO:HJD]

organism-modification


PR:000026469
ATP-dependent 6-phosphofructokinase, liver type isoform 1 phosphorylated 2 (mouse)
mPFKL/iso:1/Phos:2
"An ATP-dependent 6-phosphofructokinase, liver type isoform 1 phosphorylated 2 in mouse. UniProtKB:P12382-1, Ser-775, MOD:00046." [PMID:19131326, PRO:HJD]

organism-gene


PR:P17858
ATP-dependent 6-phosphofructokinase, liver type (human)
hPFKL
"An ATP-dependent 6-phosphofructokinase, liver type that is encoded in the genome of human." [PRO:DNx, UniProtKB:P17858]

organism-sequence


PR:P17858-1
ATP-dependent 6-phosphofructokinase, liver type isoform 1 (human)
hPFKL/iso:1
"An ATP-dependent 6-phosphofructokinase, liver type isoform 1 that is encoded in the genome of human." [PRO:CNA]

organism-sequence


PR:P17858-2
ATP-dependent 6-phosphofructokinase, liver type isoform h2 (human)
hPFKL/iso:h2
"An ATP-dependent 6-phosphofructokinase, liver type (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17858-2." [PRO:DNx, UniProtKB:P17858]

organism-modification


PR:000027299
ATP-dependent 6-phosphofructokinase, liver type, initiator methionine removed form (human)
hPFKL/InitMet-
"An ATP-dependent 6-phosphofructokinase, liver type, initiator methionine removed form in human. Example: UniProtKB:P17858-1, 2-780." [PRO:DNx]

Yes
organism-modification


PR:000055950
ATP-dependent 6-phosphofructokinase, liver type N-glycosylated 1 (human)
hPFKL/NGlyco:1
"An ATP-dependent 6-phosphofructokinase, liver type (human) that has been N-glycosylated at the residue equivalent to Asn-399 of the amino acid sequence represented by UniProtKB:P17858-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P17858-1, Asn-399, MOD:00160~GNO:G00912UN." [GlyGen:P17858-1, PMID:29671580, PRO:DNx]

organism-modification


PR:000067082
ATP-dependent 6-phosphofructokinase, liver type methylated 1 (human)
hPFKL/Me:1
"An ATP-dependent 6-phosphofructokinase, liver type (human) that has been methylated on the residue at the position equivalent to Cys-653 of the amino acid sequence represented by UniProtKB:P17858-1. Example: UniProtKB:P17858-1, Cys-653, MOD:00660." [IEDB_epitope:1007814, PRO:DNx]

organism-modification


PR:000072100
ATP-dependent 6-phosphofructokinase, liver type methylated 2 (human)
hPFKL/Me:2
"An ATP-dependent 6-phosphofructokinase, liver type (human) that has been methylated on the residue at the position equivalent to Cys-708 of the amino acid sequence represented by UniProtKB:P17858-1. Example: UniProtKB:P17858-1, Cys-708, MOD:00660." [IEDB_epitope:1006115, PRO:DNx]

organism-gene


PR:P30835
ATP-dependent 6-phosphofructokinase, liver type (rat)
rPFKL
"An ATP-dependent 6-phosphofructokinase, liver type that is encoded in the genome of rat." [OMA:P30835, PRO:DNx]

sequence


PR:000026459
ATP-dependent 6-phosphofructokinase, liver type isoform 1
PFKL/iso:1
"An ATP-dependent 6-phosphofructokinase, liver type that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12382-1 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:P12382-1
ATP-dependent 6-phosphofructokinase, liver type isoform 1 (mouse)
mPFKL/iso:1
"An ATP-dependent 6-phosphofructokinase, liver type isoform 1 that is encoded in the genome of mouse." [PMID:18034455, PMID:19131326, PMID:296989, PRO:HJD]

Yes
organism-modification


PR:000026468
ATP-dependent 6-phosphofructokinase, liver type isoform 1 phosphorylated 1 (mouse)
mPFKL/iso:1/Phos:1
"An ATP-dependent 6-phosphofructokinase, liver type isoform 1 phosphorylated 1 in mouse. UniProtKB:P12382-1, Tyr-640, MOD:00048." [PMID:18034455, PRO:HJD]

organism-modification


PR:000026469
ATP-dependent 6-phosphofructokinase, liver type isoform 1 phosphorylated 2 (mouse)
mPFKL/iso:1/Phos:2
"An ATP-dependent 6-phosphofructokinase, liver type isoform 1 phosphorylated 2 in mouse. UniProtKB:P12382-1, Ser-775, MOD:00046." [PMID:19131326, PRO:HJD]

organism-sequence


PR:P17858-1
ATP-dependent 6-phosphofructokinase, liver type isoform 1 (human)
hPFKL/iso:1
"An ATP-dependent 6-phosphofructokinase, liver type isoform 1 that is encoded in the genome of human." [PRO:CNA]

modification


PR:000026461
ATP-dependent 6-phosphofructokinase, liver type isoform 1 phosphorylated 1
PFKL/iso:1/Phos:1
"An ATP-dependent 6-phosphofructokinase, liver type isoform 1 that has been phosphorylated on the residue at the position equivalent to Tyr-640 of the amino acid sequence represented by UniProtKB:P12382-1. Example: UniProtKB:P12382-1, Tyr-640, MOD:00048." [PMID:18034455, PRO:HJD]

organism-modification


PR:000026468
ATP-dependent 6-phosphofructokinase, liver type isoform 1 phosphorylated 1 (mouse)
mPFKL/iso:1/Phos:1
"An ATP-dependent 6-phosphofructokinase, liver type isoform 1 phosphorylated 1 in mouse. UniProtKB:P12382-1, Tyr-640, MOD:00048." [PMID:18034455, PRO:HJD]

modification


PR:000026462
ATP-dependent 6-phosphofructokinase, liver type isoform 1 phosphorylated 2
PFKL/iso:1/Phos:2
"An ATP-dependent 6-phosphofructokinase, liver type isoform 1 that has been phosphorylated on the residue at the position equivalent to Ser-775 of the amino acid sequence represented by UniProtKB:P12382-1. Example: UniProtKB:P12382-1, Ser-775, MOD:00046." [PMID:19131326, PRO:HJD]

organism-modification


PR:000026469
ATP-dependent 6-phosphofructokinase, liver type isoform 1 phosphorylated 2 (mouse)
mPFKL/iso:1/Phos:2
"An ATP-dependent 6-phosphofructokinase, liver type isoform 1 phosphorylated 2 in mouse. UniProtKB:P12382-1, Ser-775, MOD:00046." [PMID:19131326, PRO:HJD]

modification


PR:000026654
ATP-dependent 6-phosphofructokinase, liver type isoform 1, initiator methionine removed form
PFKL/iso:1/InitMet-
"An ATP-dependent 6-phosphofructokinase, liver type isoform 1 that has had the initiator methionine removed." [PRO:DNx]

modification


PR:000020936
ATP-dependent 6-phosphofructokinase, liver type, initiator methionine removed form
PFKL/InitMet-
"An ATP-dependent 6-phosphofructokinase, liver type that has had the initiator methionine removed." [PRO:DNx]

modification


PR:000026654
ATP-dependent 6-phosphofructokinase, liver type isoform 1, initiator methionine removed form
PFKL/iso:1/InitMet-
"An ATP-dependent 6-phosphofructokinase, liver type isoform 1 that has had the initiator methionine removed." [PRO:DNx]

organism-modification


PR:000027299
ATP-dependent 6-phosphofructokinase, liver type, initiator methionine removed form (human)
hPFKL/InitMet-
"An ATP-dependent 6-phosphofructokinase, liver type, initiator methionine removed form in human. Example: UniProtKB:P17858-1, 2-780." [PRO:DNx]

Yes
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PFKL forms found in complexes   

PFKL Component
 Complexes
PR:000012582 PFKL PR:000027280 6-phosphofructokinase complex PL3
PR:000027281 6-phosphofructokinase complex M3L
PR:000027282 6-phosphofructokinase complex P3L
PR:000027283 6-phosphofructokinase complex M2L2
PR:000027285 6-phosphofructokinase complex ML3
PR:000027286 6-phosphofructokinase complex, liver-type homotetramer
PR:000027288 6-phosphofructokinase complex P2L2
PR:000027299 hPFKL/InitMet- PR:000027396 6-phosphofructokinase complex P2L2 (human)
PR:000027400 6-phosphofructokinase complex PL3 (human)
PR:000027413 6-phosphofructokinase complex M3L (human)
PR:000027414 6-phosphofructokinase complex P3L (human)
PR:000027415 6-phosphofructokinase complex M2L2 (human)
PR:000027419 6-phosphofructokinase complex ML3 (human)
PR:000027421 6-phosphofructokinase complex L4 (human)
PR:P12382ZDASHZ1 mPFKL/iso:1 PR:000027027 6-phosphofructokinase complex, liver-type homotetramer (mouse)
PR:000037007 ATP-dependent 6-phosphofructokinase, liver type isoform 1 monomer (mouse)